김예경 교수
Ye Kyung Kim
서울대학교 · 의학
연구실 소개
김예경 교수의 연구실은 소아 감염병 및 면역학 분야에서 활동하며, 특히 코로나19 패안 기간 동안 어린이의 감염병 역학 변화와 면역 반응에 중점을 두고 있습니다. 신종 코로나바이러스 감염증(코로나19)이 다양한 바이러스 감염(예: RSV, PIV3) 및 세균성 병원체(예: 폐렴균, 색소균)에 미치는 영향을 분석하며, 소아에서의 면역 반응과 백신 개발에 기여하고자 합니다. 또한 다학제적 접근을 통해 감염병의 임상적 특성과 예후 요인을 규명하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Compared with the delta period, the proportions of young children and patients with complex comorbidities were higher during the omicron period in Korea. Patients with complex chronic diseases, especially neurologic diseases, had a high risk of severe coronavirus disease 2019 in the two distinct variant-dominant periods.
1/2 https://jkms.org Kawasaki disease (KD) is an acute febrile systemic vasculitis of early childhood with a predilection for the coronary arteries. Since the recent reports from the North America and European countries on Kawasaki-like disease or multisystem inflammatory syndrome in children (MIS-C) possible association with coronavirus disease-19 (COVID-19), 1,2 we explored whether this has been observed in Korean children. The incidence of KD in Korea is estimated to 217.2 per 100,000 childre
We observed changes in the epidemiology and clinical presentation of PIV3 and RSV B infections in Korean children during the COVID-19 pandemic.
These results collectively present the humoral immune responses during SARS-CoV-2 infection in children. A further longitudinal study is needed to thoroughly understand the immune system and for effective vaccine development in children during the COVID-19 pandemic.
Compared to the previous outbreak in 2014-2016, the overall macrolide resistance remained high; however, an increasing proportion of macrolide resistance was observed within ST14 strains in 2019-2020.
The NPIs implemented during the COVID-19 pandemic reduced invasive diseases caused by S. pneumoniae and Salmonella spp. but not S. aureus, S. agalactiae and E. coli in children.
Considering the mild degree of coronavirus disease 2019 (COVID-19) in children and the enormous stress caused by isolation in unfamiliar places, policies requiring mandatory isolation at medical facilities should be reevaluated especially given the impact of the pandemic on the availability of hospital beds. In this study, we assessed the usefulness of facility isolation and the transmissibility of severe acute respiratory syndrome coronavirus 2 by infected children to uninfected caregivers in i
Our results suggest moderate protection (53.4%) of IIV3 against RT-PCR laboratory-confirmed influenza in children in the 2017-2018 influenza season. However, the RIDT hampered the validity to assess VE during influenza season. Caution is needed when interpreting an RIDT-based test negative design influenza VE study.
<i>Y. pseudotuberculosis</i> infection is an infrequent cause of interstitial nephritis presenting with AKI. When a patient presents with fever, gastroenteritis, and AKI not resolving despite hydration, the clinician should suspect <i>Y. pseudotuberculosis</i> infection.
Despite its similar severity among most SARS-CoV-2-naïve children and adolescents, the delta variant may affect COVID-19 severity in those with high-risk underlying medical conditions. Underlying conditions, particularly obesity, may cause severe COVID-19 in children and adolescents, warranting strong consideration for vaccinating high-risk children.
본 연구는 한·중 양국간 외교 분쟁의 가능성이 높은 중국 조선족 문제의 근본적인 원인을 양국의 인식 차이에서 비롯된다고 가정하고 있으며, 이러한 한·중 간 인식차이를 규명하기 위한 방법으로, '한국과 중국의 중국 조선족 연구기관, 연구자 및 연구경향'을 비교분석하였다. 이를 위한 자료는 북경 현지조사 및 전문가와의 인터뷰, 인터넷 검색 등을 통해 수집하였다. 연구결과 양국은 중국 조선족에 대한 관심영역 및 기대치 등 조선족 문제를 인식하는 태도에서 분명한 차이가 존재하고 있으며, 그 원인은 한국과 중국이 각각 단일민족국가와 다민족국가라는 민족구성에서의 구조적인 차이에서 비롯된 것이라고 할 수 있다. 또한, 최근 중국 조선족의 다양한 활동을 통해, 조선족은 한·중 관계의 단순한 부산물이 아닌 중간적 존재로서, 스스로 자기정체성을 찾고, 자신의 생존 공간 및 활로를 개척하는 역동적인 존재로 파악해야 한다는 시사점을 갖게 한다.
Between 2014 and 2019, the proportion of children carrying serotype 23A increased significantly, while the carriage rate of NTHi decreased. Continuous surveillance is needed to assess the long-term effects of the PCVs on carriage dynamics of pneumococcus and NTHi.
These findings can facilitate identification of children at high risk of severe or critical COVID-19, who may require intensive medical support, and development of vaccination policies.
Purpose: Common human coronaviruses (HCoVs) are relatively understudied due to the mild nature of HCoV infection. Given the lack of local epidemiology data on common HCoVs, we aimed to describe clinical and epidemiological characteristics of common HCoVs in children. Methods: Respiratory viral test results from 9,589 respiratory samples from Seoul National University Children's Hospital were analyzed from January 2015 to December 2019. Viral detection was done by the multiplex reverse transcript
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