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임예지 교수

Yejee Lim

서울대학교 · 의학

연구실 소개

임예지 교수의 연구실은 산화 스트레스와 DNA 손상, 특히 8-옥시구아닌 관련 복합 메커니즘을 중심으로 암 유발 메커니즘을 규명하는 데 초점을 맞추고 있습니다. 특히 섬유질 미세먼지인 아스ベスト이 유전자에 미치는 영향과 그 복구 기전을 분석하며, 산화적 손상과 관련된 효소 및 유전자 발현 변화를 고성능 분석 기법을 통해 연구하고 있습니다. 또한, 임상적 응용 분야로는 심혈관계 질환 예방을 위한 약물 전처리 효과나, 노인 환자 대상의 스마트 기반 간병 기술 개발 등 실용적 의료 기술의 발전에도 기여하고 있습니다.

산화 스트레스DNA 손상 복구아스베스트 유전자 영향스마트 간병 기술임상 생물학적 마커

연구 현황

논문 수
81
총 인용 수
978
최근 5년 논문
44
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
44총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
373총합
20212022202320242025

주요 논문

15
1
논문|인용수 87·2001
Changes in DNA 8-hydroxyguanine levels, 8-hydroxyguanine repair activity, and hOGG1 and hMTH1 mRNA expression in human lung alveolar epithelial cells induced by crocidolite asbestos
H.-N. Kim, Yasuo Morimoto, Tohru Tsuda, Yuko Ootsuyama, Masami Hirohashi, Tatsuya Hirano, Isamu Tanaka, Yejee Lim, Im Goung Yun, Hiroshi Kasai
SJR Q1FWCI 9.8CarcinogenesisOA

We examined 8-hydroxyguanine (8-OH-Gua) formation and 8-OH-Gua repair enzyme activity in pulmonary type-II-like epithelial cells to determine whether oxidative stress induced by asbestos plays a role in its carcinogenic mechanism. A549 cells were incubated with crocidolite asbestos at concentrations of 0, 10, 50 and 100 microg/ml over 27 h. We then evaluated 8-OH-Gua formation, 8-OH-Gua repair enzyme activity and gene expression of 8-oxoguanine-DNA glycosylase 1 (hOGG1) and human MUtT homologue

Pulmonary and Respiratory MedicineMedicine
2
논문|인용수 63·2013
Bisphosphonate use and subsequent hip fracture in South Korea
Young‐Kyun Lee, Yong‐Chan Ha, Hyung Jin Choi, Suhyun Jang, C. Park, Yejee Lim, Chan Soo Shin
SJR Q1FWCI 4.1Osteoporosis International
SurgeryMedicine
3
논문|인용수 55·2003
Cytotoxicity of yellow sand in lung epithelial cells
Young-Hoon Kim, K. S. Kim, Noh‐Jin Kwak, K. H. Lee, Seho Kweon, Yejee Lim
SJR Q2FWCI 1.2Journal of Biosciences
PollutionEnvironmental Science
4
논문|인용수 52·2022
Bone mineral density and lipid profiles in older adults: a nationwide cross-sectional study
Jinyoung Kim, Jeonghoon Ha, Chaiho Jeong, Jeongmin Lee, Yejee Lim, Kwanhoon Jo, Mee Kyoung Kim, Hyuk‐Sang Kwon, Ki‐Ho Song, Ki‐Hyun Baek
SJR Q1FWCI 8.8Osteoporosis International
Orthopedics and Sports MedicineMedicine
5
논문|인용수 51·2006
Pretreatment with intracoronary adenosine reduces the incidence of myonecrosis after non-urgent percutaneous coronary intervention: a prospective randomized study
Chi‐Hang Lee, Adrian F. Low, Bee Choo Tai, M. Co, Mark Y. Chan, Joline S.J. Lim, Yejee Lim, Huay Cheem Tan
SJR Q1FWCI 2.8European Heart JournalOA

Pretreatment with 50 microg of adenosine decreases the incidence of myonecrosis after non-urgent PCI compared with that without pretreatment.

Cardiology and Cardiovascular MedicineMedicine
6
논문|인용수 43·1999
Silica-induced apoptosis in vitro and in vivo
Yejee Lim
SJR Q2FWCI 2.2Toxicology Letters
Pulmonary and Respiratory MedicineMedicine
7
논문|인용수 39·2021
A Smart Diaper System Using Bluetooth and Smartphones to Automatically Detect Urination and Volume of Voiding: Prospective Observational Pilot Study in an Acute Care Hospital
Jae Ho Cho, Jung‐Yeon Choi, Nak‐Hyun Kim, Yejee Lim, Jung Hun Ohn, Eun Sun Kim, Jiwon Ryu, Jangsun Kim, Yiseob Kim, Sun‐wook Kim, Kwang‐Il Kim
SJR Q1FWCI 15.6Journal of Medical Internet ResearchOA

The smart diaper system showed acceptable accuracy for measuring urine volume and it could replace conventional FVCs in acute setting hospitals. Furthermore, the smart diaper system has the potential advantage of preventing IAD development and bed sore worsening. However, the detection rate of the smart diaper system was lower than expected. Detection rate polarization among participants was observed, and improvements in the user interface and convenience are needed for older individuals who are

Occupational TherapyHealth Professions
8
논문|인용수 37·2022
Intraperitoneal drain placement and outcomes after elective colorectal surgery: international matched, prospective, cohort study
EuroSurg Collaborative, A Sgrò, Ruth Blanco‐Colino, WUR Ahmed, N Brindl, RR Gujjuri, P Lapolla, EC Mills, S Pérez-Ajates, AS Soares, Chris Varghese, William Xu
SJR Q1FWCI 9.2British journal of surgeryOA

Intraperitoneal drain placement after elective colorectal surgery is not associated with earlier detection of postoperative collections, but prolongs hospital stay and increases SSI risk.

Emergency MedicineMedicine
9
논문|인용수 33·2000
Mechanism of refractory ceramic fiber- and rock wool-induced cytotoxicity in alveolar macrophages
K.-A. Kim, W. K. Lee, J. K. Kim, Min Seok Seo, Yejee Lim, K.-H. Lee, Gue‐Tae Chae, S.-H. Lee, Y. Chung
SJR Q1FWCI 0.2International Archives of Occupational and Environmental HealthOA
NephrologyMedicine
10
논문|인용수 21·2016
Decreased Plasma Levels of Sclerostin But Not Dickkopf-1 are Associated with an Increased Prevalence of Osteoporotic Fracture and Lower Bone Mineral Density in Postmenopausal Korean Women
Yejee Lim, Chong Hwa Kim, Sunyoung Lee, Hyeonmok Kim, Seong Hee Ahn, Seung Hun Lee, Jung‐Min Koh, Yumie Rhee, Ki Hyun Baek, Yong‐Ki Min, Deog‐Yoon Kim, Beom‐Jun Kim
SJR Q1FWCI 1.9Calcified Tissue International
Orthopedics and Sports MedicineMedicine
11
논문|인용수 13·2022
Effect of the Concomitant Use of Subcutaneous Basal Insulin and Intravenous Insulin Infusion in the Treatment of Severe Hyperglycemic Patients
Yejee Lim, Jung Hun Ohn, Joo Jeong, Jiwon Ryu, Sun‐wook Kim, Jae Ho Cho, Hee-Sun Park, Hye Won Kim, Jong-Chan Lee, Eun Sun Kim, Nak‐Hyun Kim, You Hwan Jo
SJR Q1FWCI 1.7Endocrinology and MetabolismOA

Background: No consensus exists regarding the early use of subcutaneous (SC) basal insulin facilitating the transition from continuous intravenous insulin infusion (CIII) to multiple SC insulin injections in patients with severe hyperglycemia other than diabetic ketoacidosis. This study evaluated the effect of early co-administration of SC basal insulin with CIII on glucose control in patients with severe hyperglycemia.Methods: Patients who received CIII for the management of severe hyperglycemi

Endocrinology, Diabetes and MetabolismMedicine
12
논문|인용수 10·2015
Gender- and age-group-specific associations between physical performance and bone mineral density, falls, and osteoporotic fractures in Koreans: the Chungju Metabolic Disease Cohort study
Yejee Lim, Kyung-Hee Kim, Sun-Hee Ko, Kwanhoon Cho, Eun‐Hee Jang, Seung‐Hwan Lee, Dong Jun Lim, Ki Hyun Baek, Hee-Sung Ha, Mi Sun Park, Hyeon Woo Yim, Won-Chul Lee
SJR Q2FWCI 1.4Journal of Bone and Mineral Metabolism
Physical Therapy, Sports Therapy and RehabilitationHealth Professions
13
논문|인용수 10·2019
The Effect of Coffee Consumption on the Prevalence of Diabetes Mellitus: The 2012–2016 Korea National Health and Nutrition Examination Survey
Yejee Lim, Young‐Mi Park, Sun Kyu Choi, Soyeon Ahn, Jung Hun Ohn
SJR Q1FWCI 0.7NutrientsOA

An inverse association between coffee consumption and the risk of diabetes mellitus (DM) has been observed. However, little is known about this association in Koreans, although they are now among the top global consumers of coffee. Therefore, the aim of this study was to evaluate the association between the prevalence of DM and the amount of coffee consumption using a unit of exact measurement, regardless of the type of coffee consumed. This study was based on data acquired from the Korea Nation

Nutrition and DieteticsNursing
14
논문|인용수 8·2019
Changes in trabecular bone score and bone mineral density following allogeneic hematopoietic stem cell transplantation
Yejee Lim, Ki Hyun Baek, Hee‐Je Kim, Seok Lee, Jong Wook Lee, Moo-Il Kang
SJR Q1FWCI 0.6Bone
Orthopedics and Sports MedicineMedicine
15
논문|인용수 7·2014
Variable selection in quantile regression when the models have autoregressive errors
임예지, 오희석

This paper considers a problem of variable selection in quantile regression with autoregressiveerrors. Recently, Wu and Liu (2009) investigated the oracle properties of the SCADand adaptive-LASSO penalized quantile regressions under non identical but independenterror assumption. We further relax the error assumptions so that the regression modelcan hold autoregressive errors, and then investigate theoretical properties for our proposedpenalized quantile estimators under the relaxed assumption. O

대표 연구 분야

Orthopedics and Sports MedicineEndocrinology, Diabetes and MetabolismOncologySurgeryCardiology and Cardiovascular MedicineEmergency Medicine

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