이예진 교수
Yejin Lee
서울대학교 · 의학
연구실 소개
이예진 교수의 연구실은 만성 호흡기질환, 특히 간질성 폐질환과 결핵 치료에서 정서적 요법과 보조 치료 전략의 유효성을 탐색하고 있습니다. 특히 폐섬유톱리스증후군(IPF) 환자의 정서적 건강과 삶의 질 향상, 당뇨병 동반 쐐기형 폐결핵 환자에서 메트포르민의 보조 항결핵 효과 등 임상적 응용에 초점을 맞추고 있습니다. 또한 신경망 기반 임베딩 기반의 고성능 유사도 검색 및 복잡한 데이터 관계를 표현하는 임베딩 축소 기법에 대한 기초 연구를 병행하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Our findings indicate that depression and anxiety are relatively common in patients with IPF. Although no significant differences were noted with regard to survival rate and hospitalization, the present study suggests that depression and anxiety significantly influence quality of life in patients with IPF.
Among cavitary pulmonary TB patients with DM, metformin can be an effective adjunctive anti-TB agent to improve sputum culture conversion after 2 months of treatment.
Repeatedly elevated serum levels of GGT were associated with a higher risk of respiratory cancer incidence, especially in men. This finding suggests that physicians can identify a person with a higher risk of respiratory cancer through a simple repeated measurement of GGT.
Certain SNPs located on chromosome 6 or the <i>HLA-DQB2</i> gene were the top-scoring SNPs for the association with susceptibility to early COPD in the Korean GENIE cohort.
Despite recent progress in the study of complex systems, reconstruction of damaged networks due to random and targeted attack has not been addressed before. In this paper, we formulate the network reconstruction problem as an identification of network structure based on much reduced link information. Furthermore, a novel method based on multilayer perceptron neural network is proposed as a solution to the problem of network reconstruction. Based on simulation results, it was demonstrated that th
The NLST criteria demonstrated sound clinical utility for lung cancer screening of high-risk patients in Korea.
Histoplasmosis is a common endemic mycosis in North, Central, and South America, but Korea is not known as an endemic area. We treated an immunocompetent Korean patient who had histoplasmosis. A 65-year-old Korean man presented with multiple pulmonary clumps of tiny nodules in the both lungs. He had been diagnosed 40 years earlier with pulmonary tuberculosis (TB) and a fungus ball had been diagnosed 4 years earlier. He denied any history of overseas travel. The patient visited our hospital with
The introduction of inhaled corticosteroids (ICS) for the management of asthma has led to a decrease in acute exacerbation of asthma. However, there are concerns regarding the safety of long-term ICS use, particularly pneumonia. Growing evidence indicates that ICS use is associated with an increased risk of pneumonia in patients with chronic obstructive pulmonary disease, whereas the risk in patients with asthma remains unclear. This review discusses the effect of ICS on pneumonia among patients
We evaluated the biological activities of five water extracts of tissue of the mottled anemone Urticina crassicornis. Most extracts exhibited broad-spectrum antimicrobial activity as determined by ultrasensitive radial diffusion assay (URDA) against gram-positive and -negative bacteria, including a fish pathogen, Aeromonas hydrophila, but no activity against fungi. The activity of the extracts was abolished by tryptic digestion, indicating that protein compounds were responsible for the antimicr
Purpose Screening for lung cancer in high-risk patients using the National Lung Screening Trial (NLST) criteria resulted in a decreased lung cancer-related mortality rate. However, whether these criteria are applicable to the Korean has not been investigated thus far. Therefore, we estimated the utility of the NLST criteria as a screening tool for lung cancer in the Korean population. Materials and Methods The total number of newly diagnosed lung cancer cases in 2013 was obtained from the Korea
In a future trial to evaluate postextubation sleep apnea in critically ill patients, pre-stratification based on the use of corticosteroids and high-flow oxygen therapy should be considered.
the initiation of COPD treatment with LAMA is associated with a reduced escalation time to triple therapy compared with ICS/LABA.
Histoplasmosis is a common endemic mycosis in North, Central, and South America, but Korea is not known as an endemic area. We treated an immunocompetent Korean patient who had histoplasmosis. A 65-year-old Korean man presented with multiple pulmonary clumps of tiny nodules in the both lungs. He had been diagnosed 40 years earlier with pulmonary tuberculosis (TB) and a fungus ball had been diagnosed 4 years earlier. He denied any history of overseas travel. The patient visited our hospital with
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