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김병재 교수

Byoung Jae Kim

서울대학교 · 의학

연구실 소개

김병재 교수의 연구실은 주로 의료 및 생물의학 분야에서 활동하며, 특히 태반 및 태류 조직에서 유래한 줄기세포의 활용과 성장인자 분리, 브랜드 관계 형성에 영향을 미치는 소비자 심리적 요인 분석, 임신 중 간질환과 태아 성장 이상 간의 연관성, 암 치료에서의 약물 내성 메커니즘 등 다양한 분야에서 다학제적 연구를 수행하고 있습니다. 특히 Wharton's jelly에서 유래한 MSC와 자연성 성장인자의 동시 확보, 암 미세환경이 항암치료 저항성에 미치는 영향 등 임상적 응용가능성이 높은 기초 연구에 초점을 맞추고 있습니다. 또한 소비자-브랜드 관계의 심리적 기반을 규명함으로써 마케팅 전략 수립에 실질적 기여를 하고 있습니다.

줄기세포성장인자암 미세환경소비자-브랜드 관계임신 합병증

연구 현황

논문 수
142
총 인용 수
1,891
최근 5년 논문
22
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
22총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
187총합
20212022202320242025

주요 논문

15
1
논문|인용수 117·2018
Non-alcoholic fatty liver disease in the first trimester and subsequent development of gestational diabetes mellitus
Seung Mi Lee, Soo Heon Kwak, Ja Nam Koo, Ig Hwan Oh, Jeong Eun Kwon, Byoung Jae Kim, Sun Min Kim, Sang Youn Kim, Gyoung Min Kim, Sae Kyung Joo, Bo Kyung Koo, Sue Shin
SJR Q1FWCI 6.6DiabetologiaOA
EpidemiologyMedicine
2
논문|인용수 111·2008
Fetal mesenchymal stem cells derived from human umbilical cord sustain primitive characteristics during extensive expansion
Chris Hyunchul Jo, Ok-Su Kim, Eun-Young Park, Byoung Jae Kim, Ji Ho Lee, Seung‐Baik Kang, Jae Hyup Lee, Hyuk‐Soo Han, Seung Hwan Rhee, Kang-Sup Yoon
SJR Q1FWCI 4.0Cell and Tissue Research
GeneticsMedicine
3
논문|인용수 105·2013
Comparison of Explant-Derived and Enzymatic Digestion-Derived MSCs and the Growth Factors from Wharton’s Jelly
Jong Hyun Yoon, Eun Youn Roh, Sue Shin, Nam Hee Jung, Eun Young Song, Ju Young Chang, Byoung Jae Kim, Hye Won Jeon
SJR Q2FWCI 2.8BioMed Research InternationalOA

Wharton's jelly is not only one of the most promising tissue sources for mesenchymal stem cells (MSCs) but also a source of natural growth factors. To prove that we can get both natural growth factors and MSCs from Wharton's jelly, we compared cellular characteristics and the level of basic fibroblast growth factor (bFGF) from samples using the explant culture method to those derived from the traditional enzymatic culture method. The levels of bFGF were 27.0 ± 11.7 ng/g on day 3, 15.6 ± 11.1 ng/

GeneticsMedicine
4
논문|인용수 87·2005
소비자-브랜드 관계 형성에의 영향 요인과 관계 성과에 관한 연구
신종칠, 강명수, 김병재

본 연구는 최근에 많은 연구가 진행되어지고 있는 소비자-브랜드 관계에 대해 보다 심층적으로 살펴보았다. 본 연구에서는 소비자-브랜드 관계 형성에 영향을 미치는 소비자 특성을 관계 마케팅적인 관점에서 살펴보고 소비자-브랜드 관계 형성에 미치는 주요 영향요인들을 도출하였다. 또한 이런 요인들에 영향받아 형성된 소비자-브랜드 관계가 기업의 마케팅 성과에 어떤 영향을 주는가를 살펴보았다. 구체적으로 본 연구에서는 소비자의 관여도, 대인관계지향성, 관계마케팅에 대한 태도 등의 소비자 특성 변수가 소비자-브랜드 관계 형성에 영향을 미치고, 형성된 소비자-브랜드 관계 구축의 성과로써 재구매 의도와 긍정적 구전 활동이 강화될 수 있다는 연구 모델을 구성하고 이를 실증연구를 통해서 살펴보았다. 실증 결과, 소비자의 관여도와 관계 마케팅에 대한 태도가 소비자-브랜드 관계 형성에 긍정적 영향을 미친다는 것을 확인할 수 있었고, 이렇게 형성된 소비자-브랜드 관계가 재구매 의도와 긍정적 구전 활동을 높인다

5
논문|인용수 82·2020
Regeneration of the rotator cuff tendon-to-bone interface using umbilical cord-derived mesenchymal stem cells and gradient extracellular matrix scaffolds from adipose tissue in a rat model
Ji-Hye Yea, Tae Soo Bae, Byoung Jae Kim, Yong Woo Cho, Chris Hyunchul Jo
SJR Q1FWCI 9.2Acta Biomaterialia
SurgeryMedicine
6
논문|인용수 69·2013
Acute Histologic Chorioamnionitis Is a Risk Factor for Adverse Neonatal Outcome in Late Preterm Birth after Preterm Premature Rupture of Membranes
Seung Mi Lee, Jeong Woo Park, Byoung Jae Kim, Chan‐Wook Park, Joong Shin Park, Jong Kwan Jun, Bo Hyun Yoon
SJR Q1FWCI 7.4PLoS ONEOA

The presence of acute histologic chorioamnionitis is associated with adverse neonatal outcome in late preterm infants born to mothers with preterm PROM.

Pediatrics, Perinatology and Child HealthMedicine
7
논문|인용수 57·2019
Nonalcoholic fatty liver disease is a risk factor for large-for-gestational-age birthweight
Seung Mi Lee, Byoung Jae Kim, Ja Nam Koo, Errol R. Norwitz, Ig Hwan Oh, Sun Min Kim, Sang Youn Kim, Gyoung Min Kim, Soo Heon Kwak, Won Kim, Sae Kyung Joo, Sue Shin
SJR Q1FWCI 3.7PLoS ONEOA

The presence of Grade 2-3 steatosis on ultrasound in early pregnancy was associated with the increased risk of delivering an LGA infant, even after adjustment for multiple confounding factors including GDM. Adiponectin may be the linking biomarker between NAFLD and LGA.

EpidemiologyMedicine
8
논문|인용수 53·2008
Identification of Proteomic Biomarkers of Preeclampsia in Amniotic Fluid Using SELDI-TOF Mass Spectrometry
Joong Shin Park, Kyoung‐Jin Oh, Errol R. Norwitz, Joong‐Soo Han, Hye-Jin Choi, Hyo Suk Seong, Yoon Dan Kang, Chan‐Wook Park, Byoung Jae Kim, Jong Kwan Jun, Hee Chul Syn
SJR Q1FWCI 8.5Reproductive Sciences
Obstetrics and GynecologyMedicine
9
논문|인용수 50·2008
Introducing pulsed low-intensity ultrasound to culturing human umbilical cord-derived mesenchymal stem cells
Jong Hyun Yoon, Eun Youn Roh, Sue Shin, Nam Hee Jung, Eun Young Song, Dong Soon Lee, Kyou Sup Han, Joung Sung Kim, Byoung Jae Kim, Hye Won Jeon, Kang Sup Yoon
SJR Q2FWCI 0.9Biotechnology Letters
GeneticsMedicine
10
논문|인용수 50·2015
STAT3-mediated IGF-2 secretion in the tumour microenvironment elicits innate resistance to anti-IGF-1R antibody
Ji Sun Lee, Ju-Hee Kang, Hye-Jin Boo, Su-Jung Hwang, Sungyoul Hong, Su-Chan Lee, Young‐Jun Park, Tae-Moon Chung, Hyewon Youn, Seung Mi Lee, Byoung Jae Kim, June-Key Chung
SJR Q1FWCI 2.7Nature CommunicationsOA

Drug resistance is a major impediment in medical oncology. Recent studies have emphasized the importance of the tumour microenvironment (TME) to innate resistance, to molecularly targeted therapies. In this study, we investigate the role of TME in resistance to cixutumumab, an anti-IGF-1R monoclonal antibody that has shown limited clinical efficacy. We show that treatment with cixutumumab accelerates tumour infiltration of stromal cells and metastatic tumour growth, and decreases overall surviva

Endocrinology, Diabetes and MetabolismMedicine
11
논문|인용수 45·2021
Metabolic Dysfunction-Associated Fatty Liver Disease and Subsequent Development of Adverse Pregnancy Outcomes
Seung Mi Lee, Young Mi Jung, E. Choi, Soo Heon Kwak, Ja Nam Koo, Ig Hwan Oh, Byoung Jae Kim, Sun Min Kim, Sang Youn Kim, Gyoung Min Kim, Sae Kyung Joo, Bo Kyung Koo
SJR Q1FWCI 3.2Clinical Gastroenterology and HepatologyOA
EpidemiologyMedicine
12
논문|인용수 44·2008
Evidence to support that spontaneous preterm labor is adaptive in nature: neonatal RDS is more common in “indicated” than in “spontaneous” preterm birth
Joon Ho Lee, Hyo Suk Seong, Byoung Jae Kim, Jong Kwan Jun, Roberto Romero, Bo Hyun Yoon
SJR Q2FWCI 2.0Journal of Perinatal MedicineOA

1) The rate of RDS is greater following "indicated" rather than spontaneous preterm birth; 2) This observation supports the view that spontaneous preterm labor is adaptive in nature.

EpidemiologyMedicine
13
논문|인용수 44·2014
Successful Conservative Management of Ruptured Ovarian Cysts with Hemoperitoneum in Healthy Women
Jee Hyun Kim, Seung Mi Lee, Ji‐Hyun Lee, Yu Ri Jo, Min Hoan Moon, Jonghwan Shin, Byoung Jae Kim, Kyu Ri Hwang, Taek Sang Lee, Kwang Bum Bai, Hye Won Jeon
SJR Q1FWCI 6.0PLoS ONEOA

Most cases of ruptured ovarian cysts with hemoperitoneum can be managed conservatively. A low diastolic blood pressure and a large amount of hemoperitoneum suggest the need for surgical intervention.

Reproductive MedicineMedicine
14
논문|인용수 35·2019
Increased biosynthesis and accumulation of cholesterol in maternal plasma, but not amniotic fluid in pre-eclampsia
Seung Mi Lee, Ju-Yeon Moon, Byeong-Yun Lim, Sun Min Kim, Chan‐Wook Park, Byoung Jae Kim, Jong Kwan Jun, Errol R. Norwitz, Man Ho Choi, Joong Shin Park
SJR Q1FWCI 3.2Scientific ReportsOA

Preeclampsia is one of the most serious complications during pregnancy, defined as development of hypertension during late pregnancy affecting other organ systems (proteinuria, thrombocytopenia, renal insufficiency, liver involvement, cerebral symptoms or pulmonary edema). Preeclampsia is known to be associated with significant dyslipidemia, but the cause or mechanism of this metabolic aberration is not clear. Quantitative analysis of cholesterol precursors and metabolites can reveal metabolic s

Obstetrics and GynecologyMedicine
15
논문|인용수 21·2011
Clinical significance of oligohydramnios in patients with preterm labor and intact membranes*,**
Byoung Jae Kim, Roberto Romero, Seung Mi Lee, Chan‐Wook Park, Joong Shin Park, Jong Kwan Jun, Bo Hyun Yoon
SJR Q2FWCI 1.8Journal of Perinatal Medicine

Patients with preterm labor and oligohydramnios are at increased risk for impending preterm delivery and intra-amniotic inflammation and, therefore, may benefit from careful surveillance.

EpidemiologyMedicine

대표 연구 분야

Obstetrics and GynecologyEpidemiologyPediatrics, Perinatology and Child HealthHematologyPulmonary and Respiratory MedicineGenetics

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