지병철 교수
Byung Chul Jee
서울대학교 · 의학
연구실 소개
지병철 교수의 연구실은 산부인과 및 생식건강 분야에서 주로 활동하며, 특히 난소내막증, 자궁내막판종, LNG-IUS의 탈출 위험 등 생식능력에 영향을 미치는 다양한 질환의 기전과 임상적 대안을 탐구하고 있습니다. 특히 생식세포의 생존과 사멸 조절, 염증성 생물학적 마커의 임상적 유용성 등 분자 수준의 기전 연구를 병행하고 있습니다. 이는 생식의학 분야에서의 정밀의료 및 개인 맞춤 치료 전략 수립에 기여하고자 하는 목적이 큽니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Clinicians need to be aware of the risk factors for spontaneous LNG-IUS expulsion because this can lead to a discontinuation of its use.
The combined data presented in this meta-analysis do not support a clinical superiority of Gonal-F over Menopur.
Our findings suggest that serum levels of sCD163 as well as IL-6 are not useful markers for ovarian endometriomas.
This work was supported by grant no. A120043 from the Korea Health Care Technology R&D Project, Ministry of Health and Welfare, Korea. None of the authors has any conflict of interest to declare.
Considerable disagreement exists regarding whether endometrial polyps should be removed before attempting natural pregnancy and before pregnancy via intrauterine insemination (IUI) or in vitro fertilization (IVF). Through a literature review, we obtained information on the impact of endometrial polyps and polypectomy on fertility outcomes. Several observational studies have suggested that women with unexplained infertility may benefit from endometrial polypectomy for a future natural pregnancy.
<i>Background/Aims: </i>The aim of this meta-analysis was to determine whether frozen embryo transfer (ET) increases ectopic pregnancy (EP) rate compared with fresh ET. <i>Methods:</i> A meta-analysis was performed of data from seven comparative studies including 13,059 pregnancies that resulted from nondonor in vitro fertilization cycles. <i>Results:</i> The EP rate was 2.31% (49/2,125 pregnancies) for frozen ET and 1.48% (162/10,934 pregnancies) for fresh ET
Adverse symptoms were common and discontinuation rate was somewhat higher during short-term course of ulipristal acetate. Information about incidence of various adverse symptoms should be given to women who willing to take ulipristal acetate.
This study was designed to investigate the role of nitric oxide (NO) on the apoptosis of human luteinized granulosa cells and its possible pathways. Granulosa cell suspensions were incubated for 48 h after adding NO donor (S-nitroso-N-acetyl-penicillamine, SNAP) and NO synthase inhibitor (nitro-L-arginine methyl ester, L-NAME) at different concentrations. Apoptosis was examined using a terminal deoxynucleotide-transferase-mediated dUTP-biotin nick end labeling method in 70 patients, and immunocy
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