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이찬미 교수

Chan Mi Lee

서울대학교 · 의학

연구실 소개

이찬미 교수의 연구실은 종양 생물학과 면역학적 기전을 중심으로, 특히 대장암 환자의 예후를 예측할 수 있는 생체지표인 미오스테아토시스의 임상적 의미를 규명하고 있습니다. 또한, 면역관찰점 억제제 치료와 관련된 희귀 부작용인 혈관염(irAE)의 임상 양상과 관리 전략에 대해서도 체계적인 분석을 수행하고 있으며, 이는 치료의 안전성 향상에 기여하고자 합니다. 뿌리내리기 연구로서 식량작물의 품질 개선을 위한 유전자 기반 품종 개발도 함께 진행 중입니다.

대장암 예후면역관찰점 억제제 부작용미오스테아토시스유전자 기반 품종 개발IgG4 관련 질환

연구 현황

논문 수
128
총 인용 수
2,323
최근 5년 논문
72
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
72총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
487총합
20212022202320242025

주요 논문

15
1
리뷰|인용수 113·2020
Prognostic impact of myosteatosis in patients with colorectal cancer: a systematic review and meta‐analysis
Chanmi Lee, Jeonghyun Kang
SJR Q1FWCI 7.6Journal of Cachexia Sarcopenia and MuscleOA

This meta-analysis demonstrates that myosteatosis is associated with worse overall survival in patients with colorectal cancer. More investigation is needed to standardize the measurement protocol for myosteatosis and to further optimize its prognostic power for colorectal cancer patients.

PhysiologyMedicine
2
논문|인용수 78·2019
Regional Variation of Human Skin Surface Temperature
Chan Mi Lee, Seon‐Pil Jin, Eun Jin Doh, Dong Hun Lee, Jin Ho Chung
SJR Q3FWCI 1.5Annals of DermatologyOA
Radiology, Nuclear Medicine and ImagingMedicine
3
논문|인용수 43·2013
Cell density during differentiation can alter the phenotype of bone marrow-derived macrophages
Chan Mi Lee, Jim Hu
SJR Q1FWCI 0.6Cell & BioscienceOA

Overall, our findings indicate that altering cell density during BMDM differentiation can give rise to distinct macrophage populations that could vary the outcome of a functional study.

ImmunologyImmunology and Microbiology
4
논문|인용수 32·2022
Risk factors for early mortality in patients with carbapenem-resistant Acinetobacter baumannii bacteraemia
Chan Mi Lee, Chung-Jong Kim, Seong Eun Kim, Kyung Hwa Park, Ji Yun Bae, Hee Jung Choi, Younghee Jung, Seung Soon Lee, Pyoeng Gyun Choe, Wan Beom Park, Eu Suk Kim, Je Eun Song
SJR Q2FWCI 2.3Journal of Global Antimicrobial ResistanceOA

Our results suggest that a large proportion of CRAB bacteraemia with high severity progresses to a rapidly fatal course, regardless of the underlying diseases or source of infection. Further studies might be needed to investigate the microbiological factors associated with CRAB and pathogen-host interaction in patients with EM.

Molecular MedicineBiochemistry, Genetics and Molecular Biology
5
논문|인용수 26·2015
Influence of Multi-Gene Allele Combinations on Grain Size of Rice and Development of a Regression Equation Model to Predict Grain Parameters
Chanmi Lee, Jonghwa Park, Backki Kim, Jeonghwan Seo, Gileung Lee, Su Jang, Hee‐Jong Koh
SJR Q1FWCI 1.7RiceOA

Rice grain size is strongly influenced by specific combinations of alleles from six different genes. A regression equation model developed from allele and grain measurement data can be used in rice breeding programs for the development of new rice varieties with desired grain size and shape.

GeneticsBiochemistry, Genetics and Molecular Biology
6
리뷰|인용수 18·2024
A scoping review of vasculitis as an immune-related adverse event from checkpoint inhibitor therapy of cancer: Unraveling the complexities at the intersection of immunology and vascular pathology
Chanmi Lee, Margaret Wang, Aarthi Rajkumar, Cassandra Calabrese, Leonard H. Calabrese
SJR Q1FWCI 5.1Seminars in Arthritis and RheumatismOA

Vasculitis as an irAE appears clinically heterogeneous and rare. Among reported cases with adequate documentation, vasculitis is of delayed onset following the initiation of immunotherapy. Outcomes of ICI-vasculitis were generally favorable, responding to glucocorticoids and immunotherapy withdrawal. There is an urgent need for more standardized reporting of rare irAEs such as vasculitis to clarify clinical risks, classification, relationship to immunotherapy and outcomes.

OncologyMedicine
7
논문|인용수 13·2022
Different clinical characteristics and impact of carbapenem-resistance on outcomes between Acinetobacter baumannii and Pseudomonas aeruginosa bacteraemia: a prospective observational study
Chan Mi Lee, Young Jun Kim, Sook‐In Jung, Seong Eun Kim, Wan Beom Park, Pyoeng Gyun Choe, Eu Suk Kim, Chung-Jong Kim, Hee Jung Choi, Shinwon Lee, Sun Hee Lee, Younghee Jung
SJR Q1FWCI 0.9Scientific ReportsOA

Abstract This study aimed to evaluate the differences in clinical characteristics and impact of carbapenem resistance (CR) on outcomes between Acinetobacter baumannii (Ab) and Pseudomonas aeruginosa (Pa) bacteraemia. We prospectively identified all patients with Ab and Pa bacteraemia in 10 hospitals over 1 year. Treatment failure was defined as all-cause 30-day mortality, persistent bacteraemia, or recurrent bacteraemia within 30 days. We included 304 Ab and 241 Pa bacteraemia cases. CR was dete

Molecular MedicineBiochemistry, Genetics and Molecular Biology
8
논문|인용수 13·2011
A novel compensation method for the anode gain non-uniformity of multi-anode photomultiplier tubes
Chan Mi Lee, Sun Il Kwon, Guen Bae Ko, Mikiko Ito, Hyun Suk Yoon, Dong Soo Lee, S. J. Hong, Jae Sung Lee
SJR Q1FWCI 2.4Physics in Medicine and Biology

The position-sensitive multi-anode photomultiplier tube (MA-PMT) is widely used in high-resolution scintillation detectors. However, the anode gain nonuniformity of this device is a limiting factor that degrades the intrinsic performance of the detector module. The aim of this work was to develop a gain compensation method for the MA-PMT and evaluate the resulting enhancement in the performance of the detector. The method employs a circuit that is composed only of resistors and is placed between

RadiationPhysics and Astronomy
9
논문|인용수 9·2023
Impact of T-Cell Engagers on COVID-19–Related Mortality in B-Cell Lymphoma Patients Receiving B-Cell Depleting Therapy
Chan Mi Lee, Pyoeng Gyun Choe, Chang Kyung Kang, Hyeon Jae Jo, Nam Joong Kim, Sung‐Soo Yoon, Tae Min Kim, Wan Beom Park, Myoung‐don Oh
SJR Q1FWCI 2.1Cancer Research and TreatmentOA

B-cell lymphoma patients treated with TCE had significantly worse outcomes from COVID-19 than those treated with RTX. TCE therapy should be used with caution in B-cell lymphoma patients during the COVID-19 epidemic.

OncologyMedicine
10
논문|인용수 8·2022
Breakthrough COVID-19 Infection During the Delta Variant Dominant Period: Individualized Care Based on Vaccination Status Is Needed
Chan Mi Lee, Eunyoung Lee, Wan Beom Park, Pyoeng Gyun Choe, Kyoung‐Ho Song, Eu Suk Kim, Sang‐Won Park
SJR Q2FWCI 0.8Journal of Korean Medical ScienceOA

In the hospitalized setting, vaccinated and unvaccinated COVID-19 patients showed different clinical features and risk of oxygen demand despite a relatively high proportion of patients in the two groups. Vaccination needs to be assessed as an initial checkpoint, and chest X-ray may be helpful for predicting severe progression in vaccinated patients.

Infectious DiseasesMedicine
11
논문|인용수 7·2016
Comprehensive comparison of normality tests: Empirical study using many different types of data
Chanmi Lee, Suhwi Park, Jaesik Jeong
Journal of the Korean Data and Information Science SocietyOA

We compare many normality tests consisting of different sources of information extracted from the given data: Anderson-Darling test, Kolmogorov-Smirnov test, Cramervon Mises test, Shapiro-Wilk test, Shaprio-Francia test, Lilliefors, Jarque-Bera test, D'Agostino' D, Doornik-Hansen test, Energy test and Martinzez-Iglewicz test. For the purpose of comparison, those tests are applied to the various types of data generated from skewed distribution, unsymmetric distribution, and distribution with diff

Statistics and ProbabilityMathematics
12
논문|인용수 7·2023
Clinical outcomes and immunological features of COVID-19 patients receiving B-cell depletion therapy during the Omicron era
Chan Mi Lee, Chan Mi Lee, Minji Kim, Seong‐Wook Park, Chang Kyung Kang, Pyoeng Gyun Choe, Nam Joong Kim, Hyeon Jae Jo, Hyun Mu Shin, Chang-Han Lee, Chang-Han Lee, Hang‐Rae Kim
SJR Q1FWCI 1.4Infectious Diseases

<b>Background:</b> The clinical outcomes and immunological features of coronavirus disease 2019 (COVID-19) patients receiving B-cell depletion therapy (BCDT), especially in Omicron variant era, have not been fully elucidated. We aimed to investigate the outcomes and immune responses of COVID-19 patients receiving BCDT during the Omicron period.<b>Methods:</b> We retrospectively compared clinical outcomes between COVID-19 patients treated with BCDT (the BCDT group) and those with the same underly

Infectious DiseasesMedicine
13
논문|인용수 6·2016
Epithelium-specific Ets transcription factor-1 acts as a negative regulator of cyclooxygenase-2 in human rheumatoid arthritis synovial fibroblasts
Chanmi Lee, Sahil Gupta, Jiafeng Wang, Elizabeth M. Johnson, Leslie J. Crofford, John C. Marshall, Mohit Kapoor, Jim Hu
SJR Q1FWCI 0.6Cell & BioscienceOA

ESE-1 acts as a negative regulator of COX-2 in human RASFs and its effect on COX-2 is NFκB-independent.

PharmacologyMedicine
14
논문|인용수 6·2022
Positivity rates of mycobacterial culture in patients with tuberculous spondylitis according to methods and sites of biopsies: An analysis of 206 cases
Chan Mi Lee, Yoonjung Lee, Seung‐Ji Kang, Chang Kyung Kang, Pyoeng Gyun Choe, Kyoung‐Ho Song, Wan Beom Park, Eu Suk Kim, Sook‐In Jung, Hong Bin Kim, Myoung‐don Oh, Kyung‐Hwa Park
SJR Q1FWCI 1.1International Journal of Infectious DiseasesOA

We demonstrated that the positivity rates of mycobacterial culture in TS were 69.0-85.3%. Paraspinal tissues as biopsy sites were significantly associated with culture positivity in needle biopsy, suggesting that targeting paraspinal tissues during needle biopsy may be the best method for diagnosing TS.

SurgeryMedicine
15
논문|인용수 6·2021
Prevalence of Multidrug-Resistant Tuberculosis in HIV/Tuberculosis Co-Infected Patients
Chan Mi Lee, Eunyoung Lee, Ji Hwan Bang, Sang‐Won Park, Wan Beom Park, Myoung‐don Oh, Nam Joong Kim
SJR Q2FWCI 0.3Infection and ChemotherapyOA

Tuberculosis (TB) is a common opportunistic infection in human immunodeficiency virus (HIV)-infected patients. Patients with multidrug-resistant (MDR)-TB have poor outcomes. This study aimed to determine the prevalence of MDR-TB in HIV/TB co-infected patients in the Korea. We reviewed the medical records of HIV/TB co-infected patients at two university hospitals between January 1998 and December 2020. During the study period, a total of 87 HIV/TB co-infected patients were identified, and drug su

Infectious DiseasesMedicine

대표 연구 분야

Molecular BiologyInfectious DiseasesOncologyEpidemiologyMolecular MedicineImmunology

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