東北大学 · 医学
Cong Huang教授の研究室は、植物遺伝学と細胞生物学を融合した多角的な研究を推進しています。特にアリウラムコットンの形質遺伝構造の解明や、骨芽細胞の分化・増殖を制御する非コーディングRNAの機能解明が主な研究テーマです。また、代謝疾患と筋力低下の関連性や、食事パターンがうつ症状に与える影響についても疫学的・分子的アプローチを組み合わせた研究を展開しています。
Figures are computed from collected data and may differ slightly.
Gossypium hirsutum L. represents the largest source of textile fibre, and China is one of the largest cotton-producing and cotton-consuming countries in the world. To investigate the genetic architecture of the agronomic traits of upland cotton in China, a diverse and nationwide population containing 503 G. hirsutum accessions was collected for a genome-wide association study (GWAS) on 16 agronomic traits. The accessions were planted in four places from 2012 to 2013 for phenotyping. The CottonSN
This population-based cross-sectional study shows for the first time that hyperuricemia is associated with poor muscle strength. Moreover, the results indicate an inverted J-shaped association between serum UA quartiles and muscle strength.
Despite extensive research on osteoblast differentiation and proliferation in mesenchymal stem cells (MSCs), the accurate mechanism remains to be further elucidated. MicroRNAs have been reported to be key regulators of osteoblast differentiation and proliferation. Here, we found that miR-144-3p is down-regulated during osteoblast differentiation of C3H10T1/2 cells. Overexpression of miR-144-3p inhibited osteogenic differentiation, whereas inhibition of miR-144-3p reversed this process. Furthermo
This prospective study is the first to reveal the combined relationship between unhealthy eating and the incidence of depressive symptoms.
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