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이기훈 교수

Gihun Lee

서울대학교 · 재료과학

연구실 소개

이기훈 교수의 연구실은 천연 고분자인 실크 세리신, 리그닌, 연어 gelatin 등을 활용한 친환경적이고 비용 효율적인 소재 개발에 주력하고 있습니다. 특히 수중 오염물질 제거를 위한 고성능 흡착재 및 약물 방출 시스템의 설계에서 천연 고분자의 구조 제어와 상호작용 메커니즘을 중심으로 연구를 전개하고 있습니다. 신경 퇴행성 질환과 세포 사멸 메커니즘에 대한 분자 생물학적 연구를 통해 천연 고분자 기반 생체재료의 응용 가능성을 넓히고 있습니다.

천연 고분자흡착재약물 방출신경 퇴행성 질환생체재료

연구 현황

논문 수
238
총 인용 수
6,595
최근 5년 논문
30
주요 분야
재료과학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
30총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
305총합
20212022202320242025

주요 논문

15
1
논문|인용수 129·2019
Surface-modified spherical lignin particles with superior Cr(VI) removal efficiency
Hyo Won Kwak, Hyunji Lee, Ki Hoon Lee
SJR Q1FWCI 7.3Chemosphere
Water Science and TechnologyEnvironmental Science
2
논문|인용수 92·2005
Application of electrospun silk fibroin nanofibers as an immobilization support of enzyme
Ki Hoon Lee, Chang‐Seok Ki, Doo Hyun Baek, Gyung Don Kang, Dae-Woo Ihm, Young Hwan Park
SJR Q2FWCI 2.4Fibers and Polymers
BiomaterialsMaterials Science
3
논문|인용수 87·2010
Refining hot-water extracted silk sericin by ethanol-induced precipitation
Han-Jin Oh, Ji Young Lee, Moo Kon Kim, In Chul Um, Ki Hoon Lee
SJR Q1FWCI 1.8International Journal of Biological Macromolecules
BiomaterialsMaterials Science
4
논문|인용수 84·2016
Preparation of Silk Sericin/Lignin Blend Beads for the Removal of Hexavalent Chromium Ions
Hyo Won Kwak, Mun-Ju Shin, Haesung Yun, Ki Hoon Lee
SJR Q1FWCI 4.9International Journal of Molecular SciencesOA

In the present study, novel adsorbents having high adsorption capability and reusability were prepared using agricultural by-products: silk sericin and lignin. Silk sericin and lignin blend beads were successfully prepared using simple coagulation methods for the removal of hexavalent chromium (Cr(VI)) from aqueous solution. A 1 M lithium chloride (LiCl)/dimethyl sulfoxide (DMSO) solvent system successfully dissolved both sericin and lignin and had sufficient viscosity for bead preparation. Comp

Organic ChemistryChemistry
5
논문|인용수 79·2017
Fabrication of an ultrafine fish gelatin nanofibrous web from an aqueous solution by electrospinning
Hyo Won Kwak, Mun-Ju Shin, Jeong Yun Lee, Haesung Yun, Dae Woong Song, Yesol Yang, Bong‐Seob Shin, Young Hwan Park, Ki Hoon Lee
SJR Q1FWCI 2.9International Journal of Biological Macromolecules
BiomaterialsMaterials Science
6
논문|인용수 71·2018
Polyethylenimine-functionalized silk sericin beads for high-performance remediation of hexavalent chromium from aqueous solution
Hyo Won Kwak, Ki Hoon Lee
SJR Q1FWCI 5.0Chemosphere
Health, Toxicology and MutagenesisEnvironmental Science
7
논문|인용수 70·2017
Fish gelatin nanofibers prevent drug crystallization and enable ultrafast delivery
Hyo Won Kwak, Heechang Woo, In‐Chul Kim, Ki Hoon Lee
SJR Q1FWCI 2.2RSC AdvancesOA

Eco-friendly and cost-effective electrospinning of aqueous fish gelatin could prevent the drug crystallization and exhibit the ultra-fast drug release behavior.

BiomaterialsMaterials Science
8
논문|인용수 70·2014
Preparation of bead-type biosorbent from water-soluble Spirulina platensis extracts for chromium (VI) removal
Hyo Won Kwak, Moo Kon Kim, Jeong Yun Lee, Haesung Yun, Min Hwa Kim, Young Hwan Park, Ki Hoon Lee
SJR Q1FWCI 4.2Algal Research
Water Science and TechnologyEnvironmental Science
9
논문|인용수 69·2007
Preparation and characterization of wet spun silk fibroin/poly(vinyl alcohol) blend filaments
Ki Hoon Lee, Doo Hyun Baek, Chang‐Seok Ki, Young Hwan Park
SJR Q1FWCI 2.8International Journal of Biological Macromolecules
BiomaterialsMaterials Science
10
논문|인용수 66·2012
Extraction conditions of Antheraea mylitta sericin with high yields and minimum molecular weight degradation
Haesung Yun, Han-Jin Oh, Moo Kon Kim, Hyo Won Kwak, Jeong Yun Lee, In Chul Um, Shyam Kumar Vootla, Ki Hoon Lee
SJR Q1FWCI 1.8International Journal of Biological Macromolecules
BiomaterialsMaterials Science
11
논문|인용수 56·2015
The role of glycerol and water in flexible silk sericin film
Haesung Yun, Moo Kon Kim, Hyo Won Kwak, Jeong Yun Lee, Min Hwa Kim, Ki Hoon Lee
SJR Q1FWCI 2.4International Journal of Biological Macromolecules
BiomaterialsMaterials Science
12
논문|인용수 55·2004
Silk Sericin Retards the Crystallization of Silk Fibroin
Ki Hoon Lee
SJR Q1FWCI 1.2Macromolecular Rapid Communications

Abstract Summary: The thermal and structural analysis of silk fibroin (SF) and silk sericin (SS) blend films reveals that the crystallization of SF is retarded in the presence of SS. Although a phase separation was observed, there might be a strong interaction at the boundary of the SF and SS through intermolecular hydrogen bonding, which restricts the conformational transition of SF. TEM image of the cross‐section of the SF/SS blend (75:25) film (magnification: ×15 000). image TEM image of the

BiomaterialsMaterials Science
13
논문|인용수 52·2017
Amyloid β1-42 (Aβ1-42) Induces the CDK2-Mediated Phosphorylation of Tau through the Activation of the mTORC1 Signaling Pathway While Promoting Neuronal Cell Death
Ki Hoon Lee, Sei‐Jung Lee, Hyun Jik Lee, Gee Euhn Choi, Young Hyun Jung, Dah Ihm Kim, Amr Ahmed Gabr, Jung Min Ryu, Ho Jae Han
SJR Q2FWCI 3.6Frontiers in Molecular NeuroscienceOA

Alzheimer's disease (AD) is a neurodegenerative disorder, characterized by cognitive impairment and memory loss. Amyloid β1-42 (Aβ) and hyper-phosphorylation of microtubule-associated protein tau have been considered as major histological features in AD. However, the mechanism of how Aβ induces the hyper-phosphorylation of tau remains to be clarified. In the present study, we investigated the underlying cellular mechanisms of Aβ with regard to the cell cycle regulatory protein-mediated phosphory

EpidemiologyMedicine
14
논문|인용수 51·2018
Magnonic quantum spin Hall state in the zigzag and stripe phases of the antiferromagnetic honeycomb lattice
Ki Hoon Lee, Suk Bum Chung, Kisoo Park, Je‐Geun Park
SJR Q1FWCI 5.0Physical review. B./Physical review. BOA

We investigated the topological property of magnon bands in the collinear magnetic orders of zigzag and stripe phases for the antiferromagnetic honeycomb lattice and identified Berry curvature and symmetry constraints on the magnon band structure. Different symmetries of both zigzag and stripe phases lead to different topological properties, in particular, the magnon bands of the stripe phase being disentangled with a finite Dzyaloshinskii-Moriya (DM) term with nonzero spin Chern number. This is

Atomic and Molecular Physics, and OpticsPhysics and Astronomy
15
논문|인용수 48·2018
Green fabrication of antibacterial gelatin fiber for biomedical application
Hyo Won Kwak, Jung Eun Kim, Ki Hoon Lee
SJR Q1FWCI 2.0Reactive and Functional Polymers
BiomaterialsMaterials Science

대표 연구 분야

BiomaterialsMolecular BiologyOncologyCondensed Matter PhysicsMaterials ChemistryAtomic and Molecular Physics, and Optics

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