장학 교수

Background The study objective was to examine the correlation between regional ventilation distribution measured with electrical impedance tomography ( EIT ) and weaning outcomes during spontaneous breathing trial ( SBT ). Methods Fifteen patients received 100% automatic tube compensation ( ATC ) during the first and 70% during the second hour. Another 15 patients received external continuous positive airway pressure ( CPAP ) of 5 and 7.5 cmH 2 O during the first and second hours, respectively.

A significant clinical problem in reconstructive surgery is partial loss of a pedicled flap. To resolve this problem, various methods of vascular augmentation have been developed; "supercharging" is one of those techniques. A new rat flap model was developed for investigation of the supercharging procedure, and the efficacy of the arterial supercharging method was examined. The purpose of this study was to investigate how an arterial supercharging procedure could generate large flap survival are

This study demonstrates that venous augmentation is also effective for increasing flap survival, and the distal procedure is more effective than the proximal procedure in arterial supercharging.

BACKGROUND Pharmacologic augmentation to mimic the delay phenomenon that increases skin flap survival has been studied extensively. Tadalafil is a phosphodiesterase V inhibitor that is used for treatment of erectile dysfunction by enhancing vascular smooth muscle relaxation. OBJECTIVE The aim of this study was to investigate the effects of local injection of tadalafil in enhancing axial-pattern skin flap survival in rats. MATERIALS AND METHODS Twenty Sprague-Dawley rats were used and a McFarlane

The subdermal plexus of the face was angiographically investigated using ten fresh cadavers injected with a radio-opaque lead oxide-gelatin mixture over the entire body. The subdermal vessels were unique in each region of the face, and the author classified the vessels into three kinds according to their running forms, shape of their skin territories, and arrangement of the territories. A kind of line by anastomoses of the subdermal vessels which are mutually adjacent or by the quite elongated s

Although silicone implants are widely used in breast and other reconstructive surgeries, the limited biocompatibility of these materials leads to severe complications, including capsular contracture. Here, we aimed to clarify the relationship between periostin and the process of capsule formation after in vivo implantation. Seven-week-old wild-type (WT) C57BL/6 mice and periostin-deficient mice were used. Round silicone implants were inserted into a subcutaneous pocket on the dorsum of the mice.

Current clinical and anatomical studies show that the venous problem associated with the deep inferior epigastric perforator flap results from poor midline-crossing. We examined the venous anatomy of the infraumbilical midline area and the dynamic venous flow of the deep inferior epigastric perforator flap in nine fresh cadavers. All nine abdominal specimens were harvested between the subcostal margin and the groin crease. Two specimens were used to analyze the abdominal venous anatomy, one of w

Grafting with compact fat that had smaller adipocytes improved the microenvironment by modulating tissue hypoxia and macrophage polarization, leading to improved graft retention. Therefore, compact fat grafting may offer a new clinical strategy without the need for stem cell manipulation.

We demonstrated that muscle free flap without reinnervation eventually converts into adipose tissue regardless of spontaneous reinnervation during muscle regeneration. The long-term findings of the present study will be valuable for muscle flap selection and prognosis.

Single-stage CFNG shows results equivalent to those of two-stage CFNG. Single-stage CFNG is associated with a shorter treatment period and fewer operations.