이학종 교수
Hak Jong Lee
서울대학교 · 의학
연구실 소개
이학종 교수의 연구실은 우수한 영상 진단 기술과 최신 내 endoscopic 및 로봇 수술 기반의 정밀 외과 치료를 융합한 연구를 주도하고 있습니다. 특히 폐암, 신장세포암, 전립선암 등에서의 영상 유도 생검, 신호 증폭 기반의 이식 전임상 영상 진단, 그리고 스마트폰 기반 저비용 내 endoscope 기술 개발에 초점을 맞추고 있습니다. 또한, 수술 중 신속한 림프절 탐지 및 암 조기 진단을 위한 분자 영상 기술과 내시경 수술 기술의 융합 연구를 지속적으로 전개하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Typical CT findings of lung cancer were ill defined consolidation-like masses at the peripheral portion where the most advanced fibrosis was located.
Prostate cancer is one of the most common neoplasms in men. Transrectal ultrasound (TRUS)-guided systematic biopsy has a crucial role in the diagnosis of prostate cancer. However, it shows limited value with gray-scale ultrasound alone because only a small number of malignancies are visible on TRUS. Recently, new emerging technologies in TRUS-guided prostate biopsy were introduced and showed high potential in the diagnosis of prostate cancer. High echogenicity of ultrasound contrast agent reflec
Cancer immunotherapy has revolutionized the way different neoplasms are treated. Among the different variations of cancer immunotherapy, the checkpoint inhibitors targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) axis have been validated and are currently used in the clinics. Nevertheless, these therapeutic antibodies are associated with significant side effects and are known to induce immune-related toxicities. To address these issues, we have developed an i
The classification system of SVL on the basis of their imaged morphologic features can provide an objective standard and simplify the abnormal findings to help predict SVI in prostate cancer. Pattern analysis of SVL with MR imaging improves the accuracy of detecting SVI.
Because chemotherapeutic drugs are often associated with serious side effects, the central topic in modern drug delivery is maximizing the localization of drugs at the target while minimizing non-specific drug interactions at unwanted regions. To address this issue, biocompatible nanoparticles have been developed to enhance the drug half-life while minimizing the associated toxicity. Nevertheless, relying solely on the enhanced half-life and enhanced permeability and retention (EPR) effects has
According to receiver operating characteristic analysis, ANN with TRUS findings was found to be more accurate than ANN without. We conclude that TRUS findings should be included as an input data component in ANN models used to diagnose prostate cancer.
A sonographic finding of echogenic fetal bowel should be interpreted cautiously because the use of special image-processing techniques can artificially enhance the apparent level of echogenicity of the bowel. We recommend rescanning without the use of those techniques if the fetal bowel appears to have an increased level of echogenicity.
The maximum cancer length was found to be the most reliable predictor of disease staging. The findings of a maximum cancer length of <0.9 cm, PSA of <16 ng/mL, and a Gleason score of <7 can suggest an organ-confined disease.
Any focal lesion on transrectal sonography with a strain index of greater than 2.4 is at risk for prostate cancer.
MDCT cystography can be used for evaluation of leaks at the anastomotic site after prostatectomy and may have a better leak detection rate than conventional cystography.
Routine TZ biopsies following 12-core systematic biopsies are not warranted for the detection of TZ cancer because of their low additional yield.
The discrepancy between prenatal sonographic and postnatal CT findings supports the assumption that regression of lung masses during serial prenatal sonographic follow-up does not always indicate their complete regression.
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