홍승노 교수
Hong, Seung-No
서울대학교 · 의학
연구실 소개
홍승노 교수의 연구실은 수면 무호흡증과 상부 호흡기 질환의 기전과 치료에 중점을 두고 있으며, 특히 만성적 경과를 보이는 비염, 비중격만곡증, 편도염 등과 연관된 상부 기도 폐쇄의 기전을 해부학적·임상적 접근으로 규명하고 있습니다. 수면 내시경, 영상 진단, 수술적 치료 전략 개발을 통해 환자의 기도 폐쇄 부위를 정밀하게 분석하고, 개인 맞춤형 수술법의 개선과 적용에 기여하고 있습니다. 특히 비염과 수면 무호흡증의 연관성, 흉부외과학적 관점에서의 혈전생성성 증가 메커니즘 등 다학제적 연구를 진행하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15These results suggest that patients with moderate to severe OSA have elevated blood coagulability markers compared with healthy individuals, which may contribute to the occurrence of cardiovascular complications.
The clinical characteristics of allergic rhinitis, including allergen-sensitization patterns and related symptoms, varied by age and sex. Six common allergens could be sufficient to generate a cost-effective tool to identify allergic rhinitis.
Expansion sphincter pharyngoplasty appears to be a promising surgical technique to reduce lateral pharyngeal collapse in patients with moderate or severe OSA. Clinical data suggest that both severe palatal circumferential narrowing and bulky lateral pharyngeal tissue are favorable surgical indications for ESP in patients with OSA.
4.
Eosinophilic angiocentric fibrosis (EAF) is a rare and slowly progressive disease, which usually involves the sino-nasal structures and upper respiratory tract. It is a fibroinflammatory lesion with an unclear etiology. Recent literature suggests a relation to rheumatic or immunological disorders. Therefore, immunophenotypic workup is critical when suspected. We report a case of a 32-year-old man complaining of nasal obstruction lasting more than 2 years. Nasal endoscopy and computed tomography
Obstructive sleep apnea (OSA) is a widespread disease of substantial social burden. As various surgical procedures are now developed to alter the offending anatomic abnormalities, identification of the exact problematic site with application of the most appropriate treatment including surgical procedure is essential for effective surgical treatment of OSA. To date, many techniques are available for the physician to assess and analyze the upper airway obstruction including radiographic cephalomet
The change in snoring rate according to the severity of AHI showed an inverted U-shaped pattern, with a peak in the moderate OSA group.
In AR, particular components of the coagulation cascade were increased and fibrinolysis system was decreased compared to normal control. This difference may be associated with the fibrin deposition in the mucosa of AR mouse model.
For the treatment of sinus surgery-induced osteitis in chronic rhinosinusitis (CRS), oral or intranasal administration of corticoids is generally used, although it has critical limitations and unavoidable side effects. To overcome these limitations, we designed dexamethasone (Dex)-loaded poly(lactic-<i>co</i>-glycolic acid) (PLGA) microparticles with bone-specific binding affinity, which could release the encapsulated Dex in a sustained manner on the exposed bone after the surgical wound in the
Since December 2019, COVID-19 has greatly influenced public healthcare systems around the globe in various aspects, including limitation of healthcare accessibility due to lack of both human and financial resources, suspension of clinics, and fear of infection causing healthcare avoidance. The aim of this study was to investigate the impact of COVID-19 on access to healthcare for otorhinolaryngology patients from different socioeconomic status (SES) groups. Otorhinolaryngology patients' disease
3 Laryngoscope, 131:E1753-E1759, 2021.
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