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구혜연 교수

Hye Yeon Koo

서울대학교 · 의학

연구실 소개

구혜연 교수의 연구실은 만성질환 예방과 건강관리를 중심으로 한 인구기반 역학 연구를 수행하고 있습니다. 특히 음주 패턴과 암 발생 간의 연관성, 금연이 심혈관계 질환에 미치는 영향, 그리고 모바일 헬스 앱의 임상적 활용 가능성을 탐색하고 있습니다. 주요 연구는 한국 국민건강보험공단 데이터를 기반으로 한 대규모 코hort 연구와 임상시험을 융합한 실증적 접근을 특징으로 합니다.

음주 패턴암 예방금연 효과모바일 헬스 앱대규모 코hort 연구

연구 현황

논문 수
53
총 인용 수
622
최근 5년 논문
32
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
32총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
344총합
20212022202320242025

주요 논문

15
1
리뷰|인용수 143·2023
Evaluation and Treatment of Obesity and Its Comorbidities: 2022 Update of Clinical Practice Guidelines for Obesity by the Korean Society for the Study of Obesity
Kyoung Kon Kim, Ji-Hee Haam, Bom Taeck Kim, Eun Mi Kim, Jung Hwan Park, Sang Youl Rhee, Eon Ju Jeon, Eungu Kang, Ga Eun Nam, Hye Yeon Koo, Jeong-Hyun Lim, Jo-Eun Jeong
SJR Q1FWCI 34.6Journal of Obesity & Metabolic SyndromeOA

The goal of the 8th edition of the Clinical Practice Guidelines for Obesity is to help primary care physician provide safe, effective care to patients with obesity by offering evidence-based recommendations to improve the quality of treatment. The Committee for Clinical Practice Guidelines comprised individuals with multidisciplinary expertise in obesity management. A steering board of seven experts oversaw the entire project. Recommendations were developed as the answers to key questions formul

PharmacologyMedicine
2
논문|인용수 67·2021
Association of the Frequency and Quantity of Alcohol Consumption With Gastrointestinal Cancer
Jung Eun Yoo, Dong Wook Shin, Kyungdo Han, Dahye Kim, Su‐Min Jeong, Hye Yeon Koo, Su Jong Yu, Jinsung Park, Kui Son Choi
SJR Q1FWCI 7.4JAMA Network OpenOA

In this cohort study, frequent drinking was a more important risk factor for incident GI cancers than the amount of alcohol consumed per occasion. Individuals should be cautioned about regular consumption of small amounts of alcohol in addition to the total amount of alcohol consumption or amount per occasion.

EpidemiologyMedicine
3
논문|인용수 50·2019
Development and Usability of a Life-Logging Behavior Monitoring Application for Obese Patients
Ju Yeon Lee, Ju Young Kim, Seung Ju You, You Soo Kim, Hye Yeon Koo, Jeong‐Hyun Kim, Sohye Kim, Jung Ha Park, Jong Soo Han, Siye Kil, Hyerim Kim, Ye Seul Yang
SJR Q1FWCI 6.9Journal of Obesity & Metabolic SyndromeOA

The Dr. Youth app shows acceptable technical effectiveness, user efficiency, and user satisfaction. Future study is warranted to establish the app's clinical efficacy.

General Health ProfessionsHealth Professions
4
논문|인용수 27·2020
Association of smoking cessation after atrial fibrillation diagnosis on the risk of cardiovascular disease: a cohort study of South Korean men
Seulggie Choi, Jooyoung Chang, Kyuwoong Kim, Sung Min Kim, Hye Yeon Koo, Mi Hee Cho, In Young Cho, Hyejin Lee, Joung Sik Son, Sang Min Park, Kiheon Lee
SJR Q1FWCI 2.5BMC Public HealthOA

Smoking cessation after AF diagnosis was associated with reduced CVD, total stroke, and ischemic stroke risk.

Cardiology and Cardiovascular MedicineMedicine
5
논문|인용수 25·2019
Efficacy of an Electronic Health Management Program for Patients With Cardiovascular Risk: Randomized Controlled Trial
Young Ho Yun, EunKyo Kang, Young Min Cho, Sang Min Park, Yong‐Jin Kim, Hae‐Young Lee, Kyae Hyung Kim, Kiheon Lee, Hye Yeon Koo, Soojeong Kim, YeEun Rhee, Jihye Lee
SJR Q1FWCI 3.5Journal of Medical Internet ResearchOA

ClinicalTrials.gov NCT03294044; https://clinicaltrials.gov/ct2/show/NCT03294044.

General Health ProfessionsHealth Professions
6
논문|인용수 25·2021
Alcohol Drinking Pattern and Risk of Head and Neck Cancer: A Nationwide Cohort Study
Hye Yeon Koo, Kyungdo Han, Dong Wook Shin, Jung Eun Yoo, Mi Hee Cho, Keun Hye Jeon, Dahye Kim, Sang-Duk Hong, Jae Kwan Jun
SJR Q2FWCI 2.6International Journal of Environmental Research and Public HealthOA

Alcohol consumption is a major risk factor for head and neck cancer (HNC), yet little data exist examining drinking patterns and HNC risk. In this population-based, retrospective cohort study, 11,737,467 subjects were recruited from the Korean National Health Insurance Service database. The risks of overall HNC and HNC subtypes according to average alcohol consumption, drinking frequency, and daily amount were examined using Cox proportional hazard models. Over the median follow-up of 6.4 years,

Pathology and Forensic MedicineMedicine
7
논문|인용수 22·2018
Effects of smoking habit change on all-cause mortality and cardiovascular diseases among patients with newly diagnosed diabetes in Korea
Mi Hee Cho, Kiheon Lee, Sang Min Park, Jooyoung Chang, Seulggie Choi, Kyuwoong Kim, Hye Yeon Koo, Ji-Hye Jun, Sung Min Kim
SJR Q1FWCI 2.5Scientific ReportsOA

This study aimed to investigate the effects of smoking habit change on the risks of all-cause mortality and cardiovascular diseases (CVDs) among patients with newly diagnosed diabetes using the Korean National Sample Cohort data. Survival regression analyses for the risks of all-cause mortality and CVDs were performed. Quitters without body mass index (BMI) change (adjusted hazard ratio [aHR], 0.68; 95% confidence interval [CI], 0.46-1.00) and quitters with BMI loss (aHR, 1.76; 95% CI, 1.13-2.73

Public Health, Environmental and Occupational HealthMedicine
8
논문|인용수 21·2019
Prevalence and Predictors of Sustained Smoking after a Cancer Diagnosis in Korean Men
Hye Yeon Koo, Kiheon Lee, Sang Min Park, Jooyoung Chang, Kyuwoong Kim, Seulggie Choi, Mi Hee Cho, Ji-Hye Jun, Sung Min Kim
SJR Q1FWCI 1.0Cancer Research and TreatmentOA

Almost half of the male smokers continue to smoke after a cancer diagnosis. Targeted interventions for smoking cessation should be considered for patients with younger age, low socioeconomic status, heavy smoking history, non-smoking-related cancer, and high blood glucose levels.

OncologyMedicine
9
논문|인용수 21·2019
Association of Concurrent Changes in Metabolic Health and Weight on Cardiovascular Disease Risk: A Nationally Representative Cohort Study
Ye Seul Bae, Seulggie Choi, Kiheon Lee, Joung Sik Son, Hyejin Lee, Mi Hee Cho, Hye Yeon Koo, In Young Cho, Jooyoung Chang, Kyuwoong Kim, Sung Min Kim, Sang Min Park
SJR Q1FWCI 1.8Journal of the American Heart AssociationOA

Background The combined effect of transitions of metabolic health and weight on cardiovascular disease (CVD) remains unclear. We aimed to examine the association of concurrent changes of metabolic health and weight on CVD over time. Methods and Results The study population consisted of 205 394 from the Korean National Health Insurance Service. Metabolic health was determined by fasting serum glucose, total cholesterol, and blood pressure levels, while obesity was determined by body mass index. A

PhysiologyMedicine
10
논문|인용수 20·2022
Fracture risk in Parkinson’s disease according to its severity and duration
Hye Yeon Koo, Eun Bin Cho, Sung Hye Kong, Kyungdo Han, Kyu Na Lee, Jung Eun Yoo, Ju‐Hong Min, Sohyun Chun, Dong Wook Shin
SJR Q1FWCI 2.0Osteoporosis International
NeurologyMedicine
11
논문|인용수 20·2016
Weight Change and Associated Factors in Long-Term Breast Cancer Survivors
Hye Yeon Koo, Young‐Gyun Seo, Mi Hee Cho, Min-Jung Kim, Ho-Chun Choi
SJR Q1FWCI 0.8PLoS ONEOA

Long-term breast cancer survivors who were non-obese at diagnosis are more likely to gain weight than obese survivors. Younger survivors and survivors who have never used AI are also likely to gain weight.

OncologyMedicine
12
논문|인용수 17·2018
Health service utilization, unmet healthcare needs, and the potential of telemedicine services among Korean expatriates
Ho Young Kim, Ju Young Kim, Hwa Yeon Park, Ji Hye Jun, Hye Yeon Koo, In Young Cho, Jinah Han, Yuliya Pak, Hyun Jung Baek, Ju Yeon Lee, Sung Hee Chang, Jung Hun Lee
SJR Q1FWCI 1.7Globalization and HealthOA

Nearly half of the expatriates in developing countries had unmet healthcare needs. Telemedicine is one potential solution to meet these needs, especially in developing countries.

General Health ProfessionsHealth Professions
13
논문|인용수 15·2017
Persistent smoking after a cardiovascular event: A nationwide retrospective study in Korea
Yoo Kyoung Lim, Dong Wook Shin, Hyeon Suk Kim, Jae Moon Yun, Jung Hyun Shin, Hye-Jin Lee, Hye Yeon Koo, Min Jung Kim, Jeong Yeon Yoon, Mi Hee Cho
SJR Q1FWCI 0.5PLoS ONEOA

Smoking is a major risk factor of cardiovascular disease (CVD) such as stroke and ischemic heart disease. Prior studies have observed people continued smoking even after being diagnosed with CVD. However, population-level data regarding smoking behavior changes among people who are diagnosed with CVD are still lacking. From the National Health Insurance sample cohort database, we identified 1,700 patients diagnosed as having CVD between 2003 and 2012, and underwent the national health screening

PhysiologyMedicine
14
논문|인용수 14·2021
Population-wide impacts of aspirin, statins, and metformin use on prostate cancer incidence and mortality
Hye Yeon Koo, Su‐Min Jeong, Mi Hee Cho, Sohyun Chun, Dong Wook Shin, Jinsung Park
SJR Q1FWCI 0.9Scientific ReportsOA

We evaluated the association between aspirin, statins, and metformin use and prostate cancer (PC) incidence and mortality using a large population-based dataset. 388,760 men who participated in national health screening program in Korea during 2002-2003 were observed from 2004 to 2013. Hazard ratios of aspirin, statins, and metformin use for PC incidence and PC mortality were calculated with adjustment for simultaneous drug use. Cumulative use of each drug was inserted as time-dependent variable

Cancer ResearchBiochemistry, Genetics and Molecular Biology
15
논문|인용수 13·2023
Metabolic syndrome and the risk of abdominal aortic aneurysm: A nationwide cohort study
In Young Cho, Hye Yeon Koo, Kyungdo Han, Kyu Na Lee, Mi Hee Cho, Sang‐Man Jin, Yang Hyun Cho, Jun Ho Lee, Yang‐Jin Park, Dong Wook Shin
SJR Q1FWCI 3.4Atherosclerosis
Pulmonary and Respiratory MedicineMedicine

대표 연구 분야

General Health ProfessionsOncologyMolecular BiologyPhysiologyEndocrinology, Diabetes and MetabolismCardiology and Cardiovascular Medicine

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