강혜진 교수
Hyejin Kang
서울대학교 · 의학
연구실 소개
강혜진 교수의 연구실은 뇌 기능의 복잡한 네트워크를 분석함으로써 인지장애 및 정서장애의 신경기반 메커니즘을 규명하는 데 초점을 맞추고 있습니다. 특히 양방향 신호 전달, 뇌파 분석(예: MEG), 그리고 영상 기반 뇌 혈류 측정을 통해 기억 및 정서 조절의 생물학적 기초를 밝혀내는 데 기여하고 있습니다. 또한, 복잡한 뇌 기능 네트워크의 구조적 특성을 수학적 도구(예: 지속 호몰로지)를 활용해 분석함으로써 뇌 기능의 상실이나 이상을 정량적으로 이해하는 데 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15The aim of this study was to identify brain areas related to apathy or depression in patients with Alzheimer disease (AD). Eighty-one AD patients were enrolled in this prospective study. 99mTc-HMPAO single photon emission computed tomography was performed to evaluate regional cerebral blood flow (rCBF). According to the Neuropsychiatric Inventory subscores of apathy and depression, 9 patients were classified as clinically significant (cs) depressed and non-cs-apathetic (D+) groups and 9 were cla
The human brain naturally integrates audiovisual information to improve speech perception. However, in noisy environments, understanding speech is difficult and may require much effort. Although the brain network is supposed to be engaged in speech perception, it is unclear how speech-related brain regions are connected during natural bimodal audiovisual or unimodal speech perception with counterpart irrelevant noise. To investigate the topological changes of speech-related brain networks at all
Supplementary data are available at Bioinformatics online.
This research attempts to examine how organizational characteristics and environmental characteristics of public organization influence adoption and application of the performance evaluation system and pay-for-performance system. In doing so, internal documents and interviews with personnel managers in KAMCO were analyzed and the adoption of system can be divided into three phases. In the process of examining each phase, it was revealed that the factors contributing to the success of establishin
To explain gating of memory encoding, magnetoencephalography (MEG) was analyzed over multi-regional network of negative correlations between alpha band power during cue (cue-alpha) and gamma band power during item presentation (item-gamma) in Remember (R) and No-remember (NR) condition. Persistent homology with graph filtration on alpha-gamma correlation disclosed topological invariants to explain memory gating. Instruction compliance (R-hits minus NR-hits) was significantly related to negative
This study showed that the proposed likelihood ratio-based false discovery rate method efficiently identifies extensive hypometabolic regions owing to its increased detection capability and ability to control the false discovery rate.
The present results suggest that late-onset deaf adults showed decreased FA and increased RD, and early-onset deaf adults showed no difference compared with the hearing group. In the late-onset deaf adults, onset-age showed a significantly positive correlation with RD and negative correlation with FA. Duration of deafness was not significantly correlated with the changes. Increased RD indicating demyelination occurred in the brain, and the changes were not limited to the auditory cortex but expa
Nine pig farms were evaluated for the welfare quality in Korea using animal- and environment-based parameters (particularly air quality parameters) during the winter of 2013. The Welfare Quality<sup>®</sup> (WQ<sup>®</sup>) protocol consists of 12 criteria within four principles. The WQ<sup>®</sup> protocol classifies farms into four categories ranging from 'excellent' to 'not classified'. Each of these criteria has specific measures for calculating scores. Calculations for the welfare scores we
ABSTRACT The self‐potential (SP) method is widely used in seepage evaluation hydrological studies to monitor the integrity of infrastructure such as dams, sea dikes, and other types of flood control devices because the electric signals that are measured are directly related to seepage rate. At leaking areas along sea dikes, large SP anomalies can be generated by the rising and falling of tides. Unfortunately, SP data are often contaminated with several types of noise, such as that from drifting
Our results suggest that oversynchronisation of left A1 connectivity before rTMS of the left A1 and DLPFC is associated with treatment effectiveness.
This study analyzes the factors influencing the organizational performance of schools in Korea, using the 'governance model'. In recent years, the importance of managerial factors in the public sector has been emphasized. To examine whether this emphasis is justified, this study analyzes data collected from the Korean Educational Panel Study wave II and III. The results of the analysis demonstrate that school leaders' managerial actions are important influential factors, as are parental factors
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