이혜진 교수
Hyejin Lee
서울대학교 · 의학
연구실 소개
이혜진 교수의 연구실은 만성질환, 특히 당뇨병과 대사질환과 관련된 자연약물의 기전 규명과 함께, 환경호르몬이 대사 이상에 미치는 영향을 중심으로 연구를 진행하고 있습니다. 특히 콩과 식물에서 유래한 천연물질의 항당뇨 효과와 지방세포 형성 조절 기전을 분석하여, 새로운 대사질환 치료 전략을 모색하고 있습니다. 또한, 사회적 참여와 정서적 건강이 뇌졸중 생존자에게 미치는 영향에 대해서도 심층적인 연구를 수행하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Community activities of PWA were very limited, and depression was highly associated with decreased community integration and QOL. Enhancing social participation and reducing emotional distress should be emphasized for rehabilitation of PWA.
This research did not receive any funding.
Delayed access to healthcare services is associated with poor outcomes and may cause different complications. Efforts are needed to prevent delays in medical use due to infectious diseases such as COVID-19. Considering the possibility of the emergence of infectious diseases, various countermeasures are needed to prevent delays in medical visit.
There is little information on how the change in serum aminotransferase affects mortality. We investigated the association between changes in serum aminotransferase levels and mortality from all causes, cardiovascular disease (CVD), and liver disease.Three percent of men from the Korean National Health Insurance database were sampled randomly at the end of 2002. After excluding patients with cancer, CVD, CVD risk factors, or liver disease, those who participated in 2 consecutive rounds of the na
The usage rate of digital devices, including mobile phones among older adults in Korea is high, whereas that of wearable devices is low. There was a notable difference in the services used by pre-frail and frail respondents compared to healthy respondents. Therefore, when developing digital devices for pre-frail and frail older adults, it is crucial to incorporate customized services that meet their unique needs, particularly those services that they frequently use.
Multiple destination trip participation has been rarely explored in the field of tourism demand studies in spite of its importance. This study investigates the determinant factors of multiple destination trips participation using a logistic regression model. Data were collected from 812 visitors to Seorak National Park on January 2009. Results indicated that the rate of the multiple destination trip participants was about 84% among the samples. Results also showed that travel distance, overnight
The aim of this study was to identify the risk factors for presence and severity of diabetic ketoacidosis (DKA) at the onset of type 1 diabetes mellitus (T1DM) in Korean children and adolescents. A retrospective chart review of children and adolescents newly diagnosed with T1DM was conducted in seven secondary and tertiary centers in Korea. Eligible subjects were < 20 years of age and had records on the presence or absence of DKA at the time of T1DM diagnosis. DKA severity was categorized as mil
None of the authors have any conflicts of interest to declare. No funding was obtained for the study.
Salmonella is one of the most common foodborne pathogens worldwide. Salmonella infections in humans are mainly associated with consumption of poultry products contaminated with this foodborne pathogen. Therefore, strict sanitary measures are necessary to control Salmonella contamination during the slaughtering process of poultry. The objective of this study was to determine the occurrence and transmission of Salmonella at a series of steps in the slaughtering process of chicken. A total of 601 s
Avian chlamydiosis is an acute or chronic bacterial disease of birds. Chlamydia psittaci is the primary agent of the disease. It is also an important zoonotic pathogen. Chlamydia avium and Chlamydia gallinacea have also been recognized as potential causative agents of the disease. Clinical signs of this disease can vary in severity. Asymptomatic infections of Chlamydia have commonly been reported in various birds worldwide. In this study, we investigated the distribution of Chlamydia species in
We developed a low-salt soy sauce from soy residue and T. molitor larvae powder. The salinity of low-salt soy sauce replaced by okara (LSO), T. molitor larvae powder (LST), or both okara and T. molitor larvae powder (LSOT) ranged between 9.87 and 12.47% with a pH of 5.4–6.3. LSO exhibited lower acidity (0.58) than LST (1.27) and LSOT (1.34). LSOT showed the highest protease activity, total nitrogen, and amino nitrogen content among the soy sauces. Glutamic acid was 10 times higher in LST and LSO
원산지별 건고추(중국산, 베트남, 국산)의 전자빔 조사처리에 따른 품질변화를 알아보고자 미생물학적 및 이화학적 품질 특성을 확인하였다. 비조사처리 건고추의 미생물 오염농도는 총 세균, 효모 및 곰팡이가 <TEX>$10^6-10^7CFU/g$</TEX>이 확인되었고, 대장균군은 베트남산에서만 <TEX>$10^3CFU/g$</TEX>이 확인되었다. 그러나 전자빔 조사처리에 의해 총 세균, 효모 및 곰팡이는 약 2-4 log cycle 정도 감소되었으며, 대장균군은 1 kGy 이상에서 검출되지 않았다. 또한 원산지에 따른 전자빔 조사처리 된 건고추의 수분, pH는 조사선량에 따른 유의적인 차이가 나타나지 않았으며, 환원당 함량은 1 kGy에서 다소 증가하는 경향이 있으나 유의적인 차이는 미미한 것으로 나타났다. 고추의 주요 매운맛 성분인 capsaicinoid함량은 중 국산(19.21 mg%), 베트남산(214.36 mg%), 국내산(7.28 mg%)으로 베트남산이 가장 높게 나타났으며,
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