진형민 교수
Hyeong Min Jin
서울대학교 · 의학
연구실 소개
진형민 교수의 연구실은 저선량 및 초저선량 CT 영상에서의 노이즈 제거와 재구성 커널에 의한 영상 품질 변동을 보정하기 위한 딥러닝 기반 영상 복원 기술에 주력하고 있습니다. 특히, 병변의 정량 분석 정확도를 높이기 위해 재구성 필터의 영향을 보정하고, 실제 임상 적용에 적합한 고해상도 영상 생성 기술을 개발하고 있습니다. 또한, MRI 유도 방사선 치료에서의 해부학적 변화에 대응하는 적응형 방사선 치료 기법의 정량적 평가도 함께 진행하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Lung densitometry is being frequently adopted in CT-based emphysema quantification, yet known to be affected by the choice of reconstruction kernel. This study presents a two-step deep learning architecture that enables accurate normalization of reconstruction kernel effects on emphysema quantification in low-dose CT. Deep learning is used to convert a CT image of a sharp kernel to that of a standard kernel with restoration of truncation artifacts and smoothing-free pixel size normalization. We
Effective elimination of unique CT noise pattern while preserving adequate image quality is crucial in reducing radiation dose to ultra-low-dose level in CT imaging practice. In this study, we present a novel Deep Learning-enable Iterative Reconstruction (Deep IR) approach for CT denoising which incorporate a synthetic sinogram-based noise simulation technique for training of Convolutional Neural Network (CNN). Regular dose CT images from 25 patients were used from Seoul National University Hosp
We demonstrated that using SGRT improves the accuracy and efficiency of initial patient setups in breast cancer patients using the Halcyon system, which has limitations in correcting the rotational offset.
This study presents a novel deep learning approach for denoising of ultra-low-dose cardiac CT angiography (CCTA) by combining a low-dose simulation technique and convolutional neural network (CNN). Twenty-five CT angiography (CTA) scans acquired with ECG gating (70 – 100 kVp, 100 – 200 mAs) were fed into the low-dose simulation tool to generate a paired set of simulated low-dose CTA and synthetic low-dose noise. A modified U-net model with 4x4 kernel size and five layers was trained with these p
Differing reconstruction kernels are known to strongly affect the variability of imaging biomarkers and thus remain as a barrier in translating the computer aided quantification techniques into clinical practice. This study presents a deep learning application to CT kernel conversion which converts a CT image of sharp kernel to that of standard kernel and evaluates its impact on variability reduction of a pulmonary imaging biomarker, the emphysema index (EI). Forty cases of low-dose chest CT exa
Purpose Online magnetic resonance-guided adaptive radiotherapy (MRgART), an emerging technique, is used to address the change in anatomical structures, such as treatment target region, during the treatment period. However, the electron density map used for dose calculation differs from that for daily treatment, owing to the variation in organ location and, notably, air pockets. In this study, we evaluate the dosimetric effect of electron density override on air pockets during online ART for panc
CT scan parameters are known to strongly affect imaging biomarker quantification and increase variability of measurements. We present a deep learning-enabled recon kernel normalization technique and its effect in emphysema quantification in low-dose lung CT.
This work demonstrated that the anthropomorphic phantom was physiologically and geometrically similar to the patient organs and was employed to quantitatively evaluate the deep-learning-based synthetic CT algorithm.
This paper presents a novel approach for generating virtual non-contrast planning computed tomography (VNC-pCT) images from contrast-enhanced planning CT (CE-pCT) scans using a deep learning model. Unlike previous studies, which often lacked sufficient data pairs of contrast-enhanced and non-contrast CT images, we trained our model on dual-energy CT (DECT) images, using virtual non-contrast CT (VNC CT) images as outputs instead of true non-contrast CT images. We used a deterministic method to co
Our study revealed that MTF of IR technique degrades depending on noise level at low dose scan. Therefore, we recommend that its characteristic should be considered in quantitative analysis such as lesion size measurement.
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