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이혜영 교수

Hyeyoung Lee

서울대학교 · 물리·천문학

연구실 소개

이혜영 교수의 연구실은 주로 생체 내 중금속 이온의 선택적 탐지 및 제거를 위한 신호 전환형 화학센서와 나노소재 기반의 생물학적 감지 기술을 핵심으로 연구하고 있습니다. 특히 lead( Pb²⁺)과 coppe( Cu²⁺)와 같은 유해 중금속 이온에 대한 고감도, 고선택성 반응 메커니즘을 규명하며, 임상적 응용과 세포 내 이온 모니터링에 응용 가능한 기술을 개발하고 있습니다. 또한, 핵반응 메커니즘과 중성자 포획 반응을 연구하는 핵물리학 분야의 기초 연구도 병행하고 있습니다.

중금속 탐지나노센서생체 내 모니터링핵반응선택적 제거

연구 현황

논문 수
321
총 인용 수
4,168
최근 5년 논문
69
주요 분야
물리·천문학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
69총합
2022
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2026
5개년 연도별 피인용 수
114총합
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주요 논문

15
1
논문|인용수 198·2009
A Selective Fluoroionophore Based on BODIPY‐functionalized Magnetic Silica Nanoparticles: Removal of Pb<sup>2+</sup> from Human Blood
Hye Young Lee, Doo Ri Bae, Ji Chan Park, Hyunjoon Song, Won Seok Han, Jong Hwa Jung
SJR Q1FWCI 11.6Angewandte Chemie International Edition

Get the lead out: The title fluorescence receptor exhibits a high affinity and selectivity for Pb(2+) over competing metal ions in water (see picture) with an overall emission change of approximately 8-fold at the emission maximum for Pb(2+). The fluorescence receptor can remove 96 % of 100 ppb Pb(2+) from human blood, and can be useful and effective for the selective and rapid removal of Pb(2+) in vivo.

SpectroscopyChemistry
2
논문|인용수 150·2011
Bidirectional Regulation of Dendritic Voltage-Gated Potassium Channels by the Fragile X Mental Retardation Protein
Hye Young Lee, Woo‐Ping Ge, Wendy C. Huang, Ye He, Gordon Wang, Ashley Rowson-Baldwin, Stephen J Smith, Yuh Nung Jan, Lily Yeh Jan
SJR Q1FWCI 8.2NeuronOA
GeneticsBiochemistry, Genetics and Molecular Biology
3
논문|인용수 38·2010
BODIPY-functionalized gold nanoparticles as a selective fluoro-chromogenic chemosensor for imaging Cu2+ in living cells
Hye Young Lee, Hyunjong Son, Jung Mi Lim, Jungmin Oh, Dongmin Kang, Won Seok Han, Jong Hwa Jung
SJR Q2FWCI 2.9The Analyst

A new fluoro-chromogenic chemosensor based on BODIPY-functionalized gold nanoparticles 1 is prepared. Addition of Cu(2+) ions to aqueous solutions of 1 gave an instantaneous color change along with a blue-shift of the absorption band and quenching of the emission spectrum at room temperature. The chemosensor 1 exhibits a high affinity and selectivity for Cu(2+) over competing metal ions tested. Moreover, confocal microscopy experiments establish that 1 can be used for detecting Cu(2+) levels wit

SpectroscopyChemistry
4
논문|인용수 34·2012
Li-glass detector response study with a 252Cf source for low-energy prompt fission neutrons
Hye Young Lee, T.N. Taddeucci, R. C. Haight, T. A. Bredeweg, A. Chyzh, M. Devlin, Ν. Fotiades, J. M. Gostic, R. Henderson, M. Jändel, E. Kwan, A. Laptev
SJR Q2FWCI 51.1Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment
Aerospace EngineeringEngineering
5
논문|인용수 31·2009
A Selective Fluoroionophore Based on BODIPY‐functionalized Magnetic Silica Nanoparticles: Removal of Pb<sup>2+</sup> from Human Blood
Hye Young Lee, Doo Ri Bae, Ji Chan Park, Hyunjoon Song, Won Seok Han, Jong Hwa Jung
FWCI 1.7Angewandte Chemie

Abstract Weg mit Blei : Der Fluoreszenzrezeptor im Titel zeichnet sich durch eine hohe Affinität und Selektivität für Pb 2+ gegenüber konkurrierenden Metallionen in Wasser aus (siehe Bild), wobei der Faktor der gesamten Emissionsänderung am Emissionsmaximum für Pb 2+ etwa 8 beträgt. Der Fluoreszenzrezeptor kann 96 % von 100 ppb Pb 2+ aus menschlichem Blut entfernen und eignet sich für die effektive, selektive und schnelle Entfernung von Pb 2+ in vivo. magnified image

SpectroscopyChemistry
6
논문|인용수 28·2010
Experimental study of the<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mmultiscripts><mml:mi mathvariant="normal">B</mml:mi><mml:mprescripts/><mml:none/><mml:mrow><mml:mn>11</mml:mn><mml:mo>,</mml:mo><mml:mn>12</mml:mn></mml:mrow></mml:mmultiscripts></mml:math>(<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mi>n</mml:mi><mml:mo>,</mml:mo><mml:mi>γ</mml:mi></mml:mrow></mml:math>) reactions and their influence on<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mi>r</mml:mi></mml:mrow></mml:math>-process nucleosynthesis of light elements
Hye Young Lee, J. P. Greene, C. L. Jiang, R. C. Pardo, K. E. Rehm, J. P. Schiffer, A. H. Wuosmaa, Nicholas Goodman, J. C. Lighthall, S. T. Marley, Kaori Otsuki, N. Patel
SJR Q1FWCI 3.7Physical Review C

We have studied the neutron-transfer reactions $^{11,12}\mathrm{B}$($d,p$)$^{12,13}\mathrm{B}$ in inverse kinematics to obtain information about the neutron-capture reactions $^{11,12}\mathrm{B}$($n,\ensuremath{\gamma}$). These capture reactions are suggested to play a role in seeding $r$-process nucleosynthesis through the production of light, neutron-rich nuclei. The neutron spectroscopic factors of the states in $^{12,13}\mathrm{B}$ were deduced and the branching ratio of the neutron-unbound

Nuclear and High Energy PhysicsPhysics and Astronomy
7
논문|인용수 27·2009
Measurement of the decay branching ratios of the<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mi>α</mml:mi></mml:mrow></mml:math>-unbound states in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mmultiscripts><mml:mi mathvariant="normal">Ne</mml:mi><mml:mprescripts/><mml:none/><mml:mrow><mml:mn>19</mml:mn></mml:mrow></mml:mmultiscripts></mml:math>and the<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mmultiscripts><mml:mi mathvariant="normal">O</mml:mi><mml:mprescripts/><mml:none/><mml:mrow><mml:mn>15</mml:mn></mml:mrow></mml:mmultiscripts><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mi>α</mml:mi><mml:mo>,</mml:mo><mml:mi>γ</mml:mi><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:math>reaction rate
Wanpeng Tan, J. Görres, M. Beard, M. Couder, A. Couture, S. Falahat, J. L. Fisker, L. O. Lamm, P. J. LeBlanc, Hye Young Lee, S. O’Brien, A. Palumbo
SJR Q1FWCI 3.6Physical Review C

The breakout reaction $^{15}\mathrm{O}(\ensuremath{\alpha},\ensuremath{\gamma})^{19}\mathrm{Ne}$ from the hot CNO cycle is critical to understanding explosive astrophysical phenomena such as x-ray bursts. In spite of considerable past experimental effort via indirect methods, this reaction rate remained mostly uncertain until our recent measurement [Phys. Rev. Lett. 98, 242503 (2007)] of the eluding $\ensuremath{\alpha}$-decay branching ratios of the near-threshold states in $^{19}\mathrm{Ne}$,

Nuclear and High Energy PhysicsPhysics and Astronomy
8
논문|인용수 17·2016
Defining “State” for the Purpose of the International Criminal Court: The Problem Ahead after the Palestine Decision
Hye‐Young Lee
SJR Q4FWCI 3.2University of Pittsburgh Law ReviewOA

In April 2012, the former ICC Prosecutor Ocampo rejected Palestine’s declaration for accepting ICC jurisdiction. The prosecutor decided that only a “state” is eligible to accept ICC jurisdiction and Palestine was not a “state” according to the UN General Assembly. So after the UN General Assembly recognized the State of Palestine seven months later, Palestine, now eligible to accept ICC jurisdiction, resubmitted its declaration and acceded to the ICC Statute in early 2015. Incumbent Prosecutor B

Political Science and International RelationsSocial Sciences
9
논문|인용수 15·2016
<sup>16</sup>O(n,<i>α</i>) cross section investigation using LENZ instrument at LANSCE
Hye Young Lee, S. Mosby, R. C. Haight, Morgan White
FWCI 1.8EPJ Web of ConferencesOA

Importance of studying the 16O(n,α) reaction is motivated by multiple nuclear applications. The Los Alamos Neutron Science Center (LANSCE) produces a white neutron spectrum ranging from thermal to several hundreds of MeV energies. We have recently developed the LENZ (Low Energy NZ-neutron induced charged particle detection) capability to measure high-precision (n,α) cross sections. In order to provide more reliable data, we have enhanced solid angle coverage, and improved signal-to-noise ratios

RadiationPhysics and Astronomy
10
논문|인용수 14·2003
Preparation and characterization of maltosyl-sucrose isomers produced by transglycosylation of maltogenic amylase from Bacillus stearothermophilus
Hye Young Lee, Myo-Jeong Kim, Jin-Sook Baek, Hee-Seob Lee, Hyun-Ju Cha, Soo‐Bok Lee, Tae-Wha Moon, Eun-Seong Seo, Doman Kim, Cheon‐Seok Park, Kwan-Hwa Park
FWCI 0.3Journal of Molecular Catalysis B Enzymatic
BiotechnologyBiochemistry, Genetics and Molecular Biology
11
논문|인용수 12·2020
New evaluation on angular distributions and energy spectra for neutron-induced charged-particle measurements
H.I. Kim, Hye Young Lee, Toshihiko Kawano, A. Georgiadou, S. A. Kuvin, Lukas Zavorka, Michal W. Herman
SJR Q2FWCI 12.6Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated EquipmentOA
Aerospace EngineeringEngineering
12
논문|인용수 11·2015
Comparison of center-of-pressure displacement during sit-to-stand according to chair height in children with cerebral palsy
Hye‐Young Lee, In-Hee Lee
FWCI 0.6Journal of Physical Therapy ScienceOA

[Purpose] In patients with cerebral palsy (CP), performance of the sit-to-stand (STS) task is influenced by an asymmetrical motor pattern. The purpose of this study was to analyze the effects of an elevated chair on STS performance in patients with CP. [Subjects and Methods] Nine CP patients performed STS from a height-adjustable instrumented chair at their natural speed, with the ankle at a 90° angle to the floor. The center-of-pressure (COP) displacement was recorded under the feet. Each foot

Psychiatry and Mental healthMedicine
13
논문|인용수 8·2005
재가 여성장애인의 건강관련 삶의 질과 관련요인 분석
이혜영, 서문자, 김세안

Purpose: The purpose of this study was to investigate the factors that influenced health related quality of life in women with disabilities. The other purpose was to examine the correlations of activities of these women's daily life, self esteem, and health promoting behavior with health related quality of life. Method: The subjects consisted of120 adult disabled women. Data was collected from February to June2004 using structured questionnaires. Spearman's correlation, and multiple regression w

14
논문|인용수 6·2015
Development of Science Subject Program based on Programming Learning to Improve Computational Thinking Ability in middle school
Hye‐Young Lee, Lee Taewuk
FWCI 0.5Journal of the Korea Society of Computer and InformationOA

In this paper, we propose a Science subject program based on programming learning to improve computational thinking ability in middle school. As the necessity of software education rises recently, the subject of information was designated as the mandatory subject in elementary, middle and high schools. In order to cultivate the ability that enables the leaners to search the knowledge in need by themselves and raise troubleshooting method, not the existing indoctrination, his thesis was willing t

Computer Science ApplicationsComputer Science
15
논문|인용수 6·2024
Differential cross sections of the <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mmultiscripts><mml:mi mathvariant="normal">O</mml:mi><mml:mprescripts/><mml:none/><mml:mn>16</mml:mn></mml:mmultiscripts><mml:mo>(</mml:mo><mml:mi>n</mml:mi><mml:mo>,</mml:mo><mml:mi>α</mml:mi><mml:mo>)</mml:mo></mml:mrow></mml:math> reaction at neutron energies from 3.8 to 15 MeV
Hye Young Lee, S. A. Kuvin, Lukas Zavorka, S. Mosby, B. DiGiovine, G. M. Hale, Mark Paris, D. Votaw, Morgan White
SJR Q1FWCI 3.6Physical review. COA

The importance of studying the $^{16}\mathrm{O}(n,\ensuremath{\alpha})$ reaction is motivated by multiple nuclear applications which rely on an accurate nuclear reaction data library for oxygen. Discrepancies between past experimental data on the $^{16}\mathrm{O}(n,\ensuremath{\alpha})^{13}\mathrm{C}$ reaction and its time-reverse $^{13}\mathrm{C}(\ensuremath{\alpha},n)^{16}\mathrm{O}$ reaction have led to various different nuclear data evaluations. We have measured $^{16}\mathrm{O}(n,\ensuremat

RadiationPhysics and Astronomy

대표 연구 분야

RadiationNuclear and High Energy PhysicsAerospace EngineeringInformation SystemsSpectroscopyNutrition and Dietetics

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