최혁진 교수

PURPOSE. To solve the shortage of donor corneas, a decellularizing method based on hypertonic saline treatment was introduced, and a favorable outcome was observed in pig-to-rabbit lamellar corneal transplantation. This study was an investigation of the efficacy of pig-to-nonhuman primate lamellar corneal transplantation, using both decellularized and fresh porcine corneas to assess feasibility as a substitute for human corneas. METHODS. Nine Chinese rhesus macaques underwent lamellar corneal tr

Anterior segment optical coherence tomography is a valuable tool for measuring the radii of anterior scleral curvatures by image processing and mathematical calculation and can provide useful information in specific clinical situations such as designing scleral lenses.

We propose a post-processing method in the wavelet transform domain that can significantly reduce the blocking effects in low-bit-rate block-transform-coded images. Although the quantization noise of the transform coefficients is the sole source of error in a coded image, the properties of block transform make the errors appear in two categories: blocky noise, which causes blocking effects, and granular (nonblocky) noise. Noting that subband coding does not suffer from blocky noise, the proposed

Our findings suggest that αGal may affect the long-term survival of porcine corneal xenografts via antibody-mediated rejection, although αGal does not have an effect on acute rejection and decellularized porcine corneas may enable the long-term survival of porcine corneal xenografts.

The purpose of this study is to investigate cross-reactivity between hypertonic saline-treated decellularized porcine corneal lamellae for corneal xenobridging and subsequent corneal allotransplants. Five Chinese rhesus macaques, which had undergone anterior partial thickness corneal transplantation using hypertonic saline-treated decellularized porcine corneal lamellae in preceding experiments, were used as recipients for subsequent full-thickness corneal allografts. To determine whether sensit

CCT is a significant factor in predicting the extent of localized RNFL defect at the initial examination of NTG patients.

Within the limits of this study, there is no evidence to support any risk of PERV transmission from porcine corneal tissues to NHP recipients, despite the existence of PERV-expressing cells in porcine corneas.

A detailed clinical trial protocol for the first corneal xenotransplantation reflecting the global guidelines is provided.

Glaucoma screening can be helpful for early detection of glaucoma. However, improvement of the screening strategy is needed in order to enhance its specificity for glaucoma.

An 18 year old male who had been taking vigabatrin for complex partial seizure was referred for visual field testing. The cumulative vigabatrin dose was about 6.0 kg over the seven and a half year period. There were bilateral symmetric visual field constrictions with greater loss of the nasal field (fig 1). On the retinal nerve fibre layer (RNFL) photographs discernible RNFL losses in the peripheral retina with a relative preservation of papillomacular bundles were observed bilaterally (fig 2).

A robust two-dimensional watermark for images which is quite secure and reliably detected under the influences of signal processing and/or geometrical alterations is proposed. The watermark is a matrix in which the rows are information-bearing pseudorandom sequences and columns are sinusoidal waves of a fixed frequency. The sinusoidal wave is used to confirm the existence of the watermark and to compensate for possible geometric distortion. To spread the energy across an image, the watermark is