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이재호 교수

Jaeho Lee

서울대학교 · 의학

연구실 소개

이재호 교수의 연구실은 태양광 발전의 효율성을 극대화하기 위한 최적 제어 기술과 의료 영상 및 생체지표를 활용한 질병 예측 모델링을 동시에 다루는 다학제적 연구를 수행하고 있습니다. 특히 태양전지의 최대출력 추적(MPPT) 알고리즘의 정밀도와 반응 속도를 향상시키는 신뢰성 높은 제어 기술 개발과 함께, 중환자실 환자의 30일 사망률 예측 지표로 활용 가능한 CRP/알부민 비율의 임상적 가치를 규명하고 있습니다. 또한 노인 환자에서의 결핵 및 항결핵제 부작용의 특성 분석을 통해 고령 환자 중심의 맞춤형 치료 전략 수립에 기여하고 있습니다.

MPPT 제어CRP/알부민 비율노령 환자 결핵항결핵제 부작용생체지표 예측 모델

연구 현황

논문 수
463
총 인용 수
8,115
최근 5년 논문
74
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
74총합
2021
2022
2023
2024
2025
5개년 연도별 피인용 수
434총합
20212022202320242025

주요 논문

15
1
논문|인용수 114·2006
Advanced Incremental Conductance MPPT Algorithm with a Variable Step Size
Jae Ho Lee, Hyunsu Bae, Bo Hyung Cho
FWCI 11.62006 12th International Power Electronics and Motion Control Conference

This paper proposes an advanced incremental conductance MPPT algorithm with a variable step size for a solar array regulator (SAR) system. This approach adjusts automatically a step size to the solar array operating point, thus improving the MPPT (maximum peak power tracking) speed and accuracy compared with the conventional method with a fixed step size. For the analysis of stability of the proposed algorithm near the maximum power point, the small signal modeling is carried out. Also, it is ve

Renewable Energy, Sustainability and the EnvironmentEnergy
2
논문|인용수 114·2018
Clinical usefulness of C-reactive protein to albumin ratio in predicting 30-day mortality in critically ill patients: A retrospective analysis
Tak Kyu Oh, In‐Ae Song, Jae Ho Lee
SJR Q1FWCI 8.8Scientific ReportsOA

This study aimed to examine the prognostic value of C-reactive protein (CRP)/albumin (ALB) ratio among patients who were admitted to the intensive care unit (ICU) in predicting 30-day mortality rate. This retrospective cohort study was conducted by examining the medical records of adult patients who were admitted to the ICU at Seoul National University Bundang Hospital between 1 January 2012 and 31 December 2016. Data from 6,972 individuals were included in the final analysis, and 547 of these i

SurgeryMedicine
3
논문|인용수 80·2005
Diagnostic and Therapeutic Problems of Pulmonary Tuberculosis in Elderly Patients
Jae Ho Lee, Dae Hee Han, Jaewoo Song, Hee Soon Chung
SJR Q2FWCI 1.2Journal of Korean Medical ScienceOA

To identify differences in the clinical, radiologic, and microbiologic features of pulmonary tuberculosis (TB) in the young (<64 yr) and elderly (> or =65 yr), we performed a retrospective analysis of the medical charts and chest radiographs of 207 young and 119 elderly pulmonary TB patients. Hemoptysis and a febrile sense were more frequent in the young, whereas weakness, dyspnea, anorexia, and mental change were more frequent in the elderly. Elderly patients showed higher frequencies of cardio

Infectious DiseasesMedicine
4
논문|인용수 66·2020
The high incidence of severe adverse events due to pyrazinamide in elderly patients with tuberculosis
Byoung Soo Kwon, Youlim Kim, Sang Hoon Lee, Sung Yoon Lim, Yeon Joo Lee, Jong Sun Park, Young‐Jae Cho, Ho Il Yoon, Choon-Taek Lee, Jae Ho Lee
SJR Q1FWCI 5.5PLoS ONEOA

PZA was the most common drug associated with SAEs among the first-line anti-TB drugs, and old age was an independent factor for SAE occurrence. This study suggests that the early recognition of whether the causative agent is PZA may improve effective treatment compliance, particularly in elderly patients.

PharmacologyPharmacology, Toxicology and Pharmaceutics
5
논문|인용수 49·2014
Ring finger protein20 regulates hepatic lipid metabolism through protein kinase A-dependent sterol regulatory element binding protein1c degradation
Jae Ho Lee, Gha Young Lee, Hagoon Jang, Sung Sik Choe, Seung‐Hoi Koo, Jae Bum Kim
SJR Q1FWCI 3.5HepatologyOA

RNF20 acts as a negative regulator of hepatic fatty acid metabolism through degradation of SREBP1c upon PKA activation. Knowledge regarding this process enhances our understanding of how SREBP1c is able to turn off hepatic lipid metabolism during nutritional deprivation.

SurgeryMedicine
6
논문|인용수 48·2016
Comparison of the Sensitivity of QuantiFERON-TB Gold In-Tube and T-SPOT.TB According to Patient Age
Won C. Bae, Kyoung Un Park, Eun Young Song, Se Joong Kim, Yeon Joo Lee, Jong Sun Park, Young‐Jae Cho, Ho Il Yoon, Jae‐Joon Yim, Choon‐Taek Lee, Jae Ho Lee
SJR Q1FWCI 3.3PLoS ONEOA

Currently, there are two types of interferon-gamma release assays (IGRAs) in use for the detection of tuberculosis (TB) infection, the QuantiFERON-TB Gold In-Tube test (GFT-GIT) and T-SPOT.TB. Owing to contradictory reports regarding whether the results of these IGRAs are affected by the age of the patient, we aimed to determine if these two tests have age-related differences in sensitivity. We retrospectively reviewed the medical records of diagnosed TB patients who were tested using either QFT

Infectious DiseasesMedicine
7
논문|인용수 47·2017
RNF20 Suppresses Tumorigenesis by Inhibiting the SREBP1c-PTTG1 Axis in Kidney Cancer
Jae Ho Lee, Yong Geun Jeon, Kyoung Hwa Lee, Hye Won Lee, Jeu Park, Hagoon Jang, Minyong Kang, Hye Sun Lee, Hee Jin Cho, Do‐Hyun Nam, Cheol Kwak, Jae Bum Kim
SJR Q2FWCI 1.8Molecular and Cellular BiologyOA

Elevated lipid metabolism promotes cancer cell proliferation. Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancers, characterized by ectopic lipid accumulation. However, the relationship between aberrant lipid metabolism and tumorigenesis in ccRCC is not thoroughly understood. Here, we demonstrate that ring finger protein 20 (RNF20) acts as a tumor suppressor in ccRCC. RNF20 overexpression repressed lipogenesis and cell proliferation by inhibiting sterol regulator

Cancer ResearchBiochemistry, Genetics and Molecular Biology
8
논문|인용수 44·2016
Factors associated with radiologic progression of non‐cystic fibrosis bronchiectasis during long‐term follow‐up
Jisoo Park, Sejoong Kim, Yeon Joo Lee, Jong Sun Park, Young‐Jae Cho, Ho Il Yoon, Kyoung‐Won Lee, Choon‐Taek Lee, Jae Ho Lee
SJR Q1FWCI 3.1Respirology

The radiologic progression of non-CF bronchiectasis was associated with lower BMI and isolation of P. aeruginosa in respiratory specimens.

Pulmonary and Respiratory MedicineMedicine
9
논문|인용수 37·2018
Characterization of Microbiota in Bronchiectasis Patients with Different Disease Severities
Sang Hoon Lee, Yeon Joo Lee, Jongsun Park, Young‐Jae Cho, Ho Il Yoon, Choon-Taek Lee, Jae Ho Lee
SJR Q1FWCI 2.9Journal of Clinical MedicineOA

The applications of the 16S rRNA gene pyrosequencing has expanded our knowledge of the respiratory tract microbiome originally obtained using conventional, culture-based methods. In this study, we employed DNA-based molecular techniques for examining the sputum microbiome in bronchiectasis patients, in relation to disease severity. Of the sixty-three study subjects, forty-two had mild and twenty-one had moderate or severe bronchiectasis, which was classified by calculating the FACED score, based

Pulmonary and Respiratory MedicineMedicine
10
논문|인용수 34·2010
Relation of ghrelin, leptin and inflammatory markers to nutritional status in active pulmonary tuberculosis
Ji Hae Kim, Choon‐Taek Lee, Ho Il Yoon, Junghan Song, Wan Gyoon Shin, Jae Ho Lee
SJR Q1FWCI 1.3Clinical Nutrition
Endocrine and Autonomic SystemsNeuroscience
11
논문|인용수 34·2014
Multivariate analysis of prognostic factors in patients with pulmonary actinomycosis
Ji Young Park, Taehoon Lee, Hongyeul Lee, Hyo-Jeong Lim, Jinwoo Lee, Jong Sun Park, Young‐Jae Cho, Young Sik Park, Chang‐Hoon Lee, Sang‐Min Lee, Ho Il Yoon, Jae‐Joon Yim
SJR Q1FWCI 4.9BMC Infectious DiseasesOA

Antibiotic treatment with or without surgery was effective for treatment of pulmonary actinomycosis. Nevertheless, treatment failure or recurrence occurred in a considerable proportion of patients, especially those resistant to the initial antibiotic treatment.

MicrobiologyMedicine
12
논문|인용수 31·2005
Diagnostic and Therapeutic Problems of Pulmonary Tuberculosis in Elderly Patients
이재호, 한대희, Jae Woo Song, 정희순
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0191120050200050784

To identify differences in the clinical, radiologic, and microbiologic features of pul-monary tuberculosis (TB) in the young (<64 yr) and elderly (≥65 yr), we performed a retrospective analysis of the medical charts and chest radiographs of 207 young and 119 elderly pulmonary TB patients. Hemoptysis and a febrile sense were more frequent in the young, whereas weakness, dyspnea, anorexia, and mental change were more frequent in the elderly. Elderly patients showed higher frequen-cies of cardiovas

13
논문|인용수 30·2015
Which Users Should Be the Focus of Mobile Personal Health Records? Analysis of User Characteristics Influencing Usage of a Tethered Mobile Personal Health Record
Guna Lee, Joong Yeol Park, Soo-Yong Shin, Jong Su Hwang, Hyeon Jeong Ryu, Jae Ho Lee, David W. Bates
SJR Q1FWCI 7.3Telemedicine Journal and e-HealthOA

This study showed that focuses on patients with chronic disease and more hospital visits and empowerment functions in a tethered m-PHR would be helpful to pursue the extensive use.

General Health ProfessionsHealth Professions
14
논문|인용수 28·2013
Lessons Learned from the Development of Health Applications in a Tertiary Hospital
Joong‐Yeol Park, Guna Lee, Soo-Yong Shin, Jeong Hun Kim, Hyewon Han, Taewan Kwon, Woo Sung Kim, Jae Ho Lee
SJR Q1FWCI 6.1Telemedicine Journal and e-HealthOA

We described the lessons learned regarding OS support, device choice, and developmental strategy. The OS can be chosen according to market share or hospital strategic plan. Smartphones were favored compared with tablets. Alliance with an information technology company can be the best way to develop apps. Health apps designed for smart devices can be used to improve healthcare. However, to develop health apps, hospitals must define their future goals and carefully consider all the aspects.

General Health ProfessionsHealth Professions
15
논문|인용수 27·2014
Proteomic Profiling of Serum from Patients with Tuberculosis
Sang Hoon Song, Minje Han, Yang Seon Choi, Kisoon Dan, Man Yang, Junghan Song, Sung Sup Park, Jae Ho Lee
SJR Q2FWCI 1.0Annals of Laboratory MedicineOA

Sera from patients with TB had higher alpha-1-antitrypsin levels than sera from control participants. Alpha-1-antitrypsin levels may aid in the diagnosis of TB.

SpectroscopyChemistry

대표 연구 분야

Pulmonary and Respiratory MedicineEpidemiologyInfectious DiseasesPharmacologyElectrical and Electronic EngineeringSurgery

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