김지현 교수

Several studies have reported a higher prevalence of chronic hepatitis C virus (HCV) infection in patients with B-cell non-Hodgkin's lymphoma and suggested a pathogenic role for HCV, but studies on hepatitis B virus (HBV) infection and non-Hodgkin's lymphoma are limited. To determine the association between HBV infection and non-Hodgkin's lymphoma, we performed a case-control study in Korea, a hepatitis B endemic area. We recruited 222 patients newly diagnosed with non-Hodgkin's lymphoma at Seou

There is ongoing debate regarding the significance of complete or near-complete response after neoadjuvant chemoradiotherapy (CRT) for rectal cancer. This study assessed the prognostic value of the Dworak tumor regression grade (TRG) following neoadjuvant CRT and surgery primarily in patients with pathological stage (ypStage) II and III rectal cancer. The records of 331 patients who underwent neoadjuvant CRT followed by total mesorectal excision between 2004 and 2015 were retrospectively reviewe

Combined pre- and postchemoradiotherapy CEA levels could be useful as a prognostic factor for disease-free survival in patients with rectal cancer who undergo treatment with neoadjuvant chemoradiotherapy and curative resection. Postchemoradiotherapy CEA may be helpful in a selection of patients who want more conservative surgery after chemoradiotherapy.

This study aimed to evaluate the efficacy of random-start controlled ovarian stimulation (COS) in cancer patients for emergency fertility preservation. In this retrospective comparative study, 22 patients diagnosed with cancer and 44 infertile women undergoing conventional in vitro fertilization (IVF) were included. In cancer patients, ovarian stimulation was started on the day of referral, irrespective of their menstrual cycle date. The control group was selected by age matching among women und

This study, which included 301 older Korean patients with cancer, highlights the increased prevalence of polypharmacy in this population planning to receive palliative chemotherapy. The prevalence of polypharmacy and excessive polypharmacy was 45.2% and 8.6%, respectively. The prescription of potentially inappropriate medications (PIMs) was detected in 45.5% and clinically significant drug-drug interaction in 30.6% of patients. Given the association of polypharmacy with increased hospitalization

Most cases of ruptured ovarian cysts with hemoperitoneum can be managed conservatively. A low diastolic blood pressure and a large amount of hemoperitoneum suggest the need for surgical intervention.

‘대학기초교양교육’의 개념에 대한 이론적 천착없이, 대학에 기대하는 사회적 기능을 충실히 수행하는 것을 기초교양교육이 제대로 이루어지는 것으로 간주하는 기능주의적 패러다임이 지배적이다. 이로 인해 대학기초교양교육은 구조가 정의되지 않는 정체혼미의 상태로 도구적 위치에 머무르며, 사회가 요구하는 소재의 무분별한 수용, 직접전달로 인한 교육활동의 왜곡과 언어주의적 결과 등의 문제를 낳고 있다. ‘대학’과 ‘교육’을 구분하며 교육학적 안목을 통한 대학기초교양교육의 재개념화가 요청된다. 기초교양교육은, 높은 수준의 교육관의 지향, 교육의 내재적 가치의 우선적 실현, 교육적 체험을 증대하는 학문 등의 다양한 지식 소재의 선택, 도제적 교육활동의 제 원리의 구현, 진리체험을 통한 지식확인과 연속적 재생 등의 원리로 이루어지는 대학교육의 한 하위영역으로 새롭게 규정될 수 있다. 오늘날 세계의 대학의 프로그램 가운데 신입생세미나, 학생독립연구, 학생주도강의, 학생설계전공, 학제적 접근의 허용으로의

Empty follicle syndrome (EFS) is a condition in which no oocytes are retrieved after an apparently adequate ovarian response to stimulation and meticulous follicular aspiration. EFS can be classified into 'genuine' and 'false' types according to hCG levels. It is a rare condition of obscure etiology. The existence of genuine EFS has been questioned and is still controversial. The limitation around EFS is that the definition of EFS is obscure. Management of patients with EFS is a challenge to phy

Our works demonstrated a significant relationship of acetylation-associated enzyme activity and strict morphology or sperm DFI.

교양교육은 ‘다양한 학문에 대한 폭넓은 이해’를 지향하는 학제성의 추구를 본질로 한다. 그럼에도 불구하고 실제로는 다양한 학문분야 교과목에 대한 분배이수 정도의 소극적 형태로만 주로 이루어져 왔으며 보다 근본적으로 이러한 교양교육에서 학제성 추구의 목적과 교과과정의 특징이 깊게 천착되지 못하였다. 본 연구는 최근 개편된 하버드대학의 교양교육의 사례를 통하여 자유교육기반 학부교육에서 교양교육이 학제성을 추구하는 목적과 이를 구현하는 교양교과과정의 특징과 의의를 확인하고자 하였다. 학제적 교양과정의 목적은 ‘대학의 자유교육을 삶에 연계시키는 것’으로서, 대학 이후의 다원적이고 융합적인 삶의 상황에서 지적인 성찰과 참여를 가능하게 하는 ‘자유교육의 유용성’을 기반으로 하여, 이 때 요청되는 능력과 태도를 함양할 수 있는 기회를 대학 교과과정 내에 구현하는 ‘자유교육의 공적 측면’으로서 교과과정의 정체성을 확보한다. 학제적 교과과정의 구성 원리는 ‘학생의 삶에 학문을 초대하기’의 접근방식을

This prospective study investigated the relationship between anti-Mllerian hormone (AMH) level in the follicular fluid (FF) and the quality of the oocyte and embryo. A total of 65 FF samples from 54 women were included in this study. FF was collected from the largest preovulatory follicle sized 20 mm of mean diameter from each ovary. Samples were divided into 3 groups according to the FF AMH levels: below the 33th percentile (low group, FF AMH < 2.1 ng/mL, n = 21), between the 33th and the 67th

This study aimed to evaluate the efficacy of random-start controlled ovarian stimulation(COS) in cancer patients for emergency fertility preservation. In this retrospectivecomparative study, 22 patients diagnosed with cancer and 44 infertile women undergoingconventional in vitro fertilization (IVF) were included. In cancer patients, ovarianstimulation was started on the day of referral, irrespective of their menstrual cycle date. The control group was selected by age matching among women undergo

The role of conversion surgery in metastatic gastric cancer remains unclear. Cancer dormancy markers might have a role in predicting the survival in patients with conversion surgery. We identified 26 patients who went through conversion surgery, i.e., a curative-intent gastrectomy with metastasectomy after chemotherapy in initially metastatic gastric cancer. As controls, 114 potential candidates for conversion surgery who only received chemotherapy were included for the propensity score matching

Pemetrexed is a newly developed multitargeted antifolate with promising clinical activity in many solid tumors including gastric cancer. The aim of the present study was to evaluate the cytotoxicity of pemetrexed and its mode of interaction with cisplatin in gastric cancer cell lines, and to identify genes associated with sensitivity to pemetrexed. The cytotoxic activity of pemetrexed was assessed by tetrazolium-based colorimetric assay (MTT assay) and the interaction between pemetrexed and cisp