김종성 교수
Jong Sung Kim
서울대학교 · 의학
연구실 소개
김종성 교수의 연구실은 뇌졸중의 기전과 치료 전략에 중점을 두고 있으며, 특히 경동맥과 내경동맥 혈관병변에 의한 뇌졸중의 기전 차이, 단일 피질하경화의 진단 및 분류, 중추성 통증의 병태생리학적 메커니즘을 규명하는 데 주력하고 있습니다. 또한, 항생제 내성 박테리아 억제를 위한 프로바이오틱스의 역할과 나노입자 노출이 폐 감염에 미치는 영향에 대해서도 기초적이고 임상적 응용을 고려한 연구를 수행하고 있습니다. 이는 뇌졸중 환자의 삶의 질 향상과 맞물려 향후 고령화 사회에 대비한 맞춤형 치료 전략 개발을 목표로 합니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15The prevalence of risk factors and stroke mechanisms differ between ICAS and ECAS, and between anterior and posterior circulation atherosclerosis. Posterior ICAS seems to be closely associated with metabolic derangement and local branch occlusion. Prevention and management strategies may have to consider these differences.
The sign language is a method of communication for the deaf-mute. Articulated gestures and postures of hands and fingers are commonly used for the sign language. This paper presents a system which recognizes the Korean sign language (KSL) and translates into a normal Korean text. A pair of data-gloves are used as the sensing device for detecting motions of hands and fingers. For efficient recognition of gestures and postures, a technique of efficient classification of motions is proposed and a f
Probiotic supplementation can reduce the antibiotic-induced alteration and imbalance of the gut microbiota composition. This effect may restrict the growth of antibiotic-resistant bacteria in the gut and improve the H. pylori eradication success rate.
Cu NP exposure impaired host defense against bacterial lung infections and induced a dose-dependent decrease in bacterial clearance in which even our lowest dose demonstrated significantly lower clearance than observed in sham-exposed mice. Thus, exposure to Cu NPs may increase the risk of pulmonary infection.
Single subcortical infarction associated with parental artery disease is an important stroke sub-type, distinct from small artery disease, illustrating that greater efforts should be made in its accurate diagnosis. Studies are needed to investigate the prevalence of single subcortical infarction associated with parental artery disease in various parts of the world and to design a stroke classification system that includes single subcortical infarction associated with parental artery disease. Pre
Pain is one of the most troublesome sequelae of stroke, occurring in 19-74% of patients. A portion of this post-stroke pain is caused by the brain lesion itself; this is called 'central post-stroke pain' (CPSP). Although the prevalence of CPSP among stroke patients is low (1-8%), the persistent, often treatment-refractory, painful sensations can be a major problem, decreasing the affected patient's quality of life. As the aging population continues to increase, CPSP will become an even more impo
The aim of this meta-analysis was to provide a comprehensive synthesis of the evidence examining biomarker signatures in MDD patients including lipids, lipid regulatory proteins (LRP), and polyunsaturated fatty acid (PUFA) as compared to healthy individuals. We performed meta-analyses and meta-regression of the studies comparing lipid, LRP, and PUFA levels between MDD patients and healthy individuals by searching Embase, Ovid Medline, Scopus, PsycINFO, PubMed, and Cochrane databases. Search was
Abstract The removal of single component and binary mixtures of divalent cobalt and iron from water by ion exchange with synthetic Y zeolite has been studied in batch, semi‐batch and continuous modes of operation; the initial metal solution concentration did not exceed 2 mmol dm −3 . Binary Co/Na and Fe/Na ion exchange equilibrium isotherms (294 K) are presented wherein exchange site heterogeneity is evident in the case of the iron treatment. Under conditions of stoichiometric ion exchange, remo
Hot-filament-assisted chemical vapor deposition has been used to study the growth morphology of synthetic diamond deposited on silicon substrate in a dilute (1 vol %) CH3COCH3/H2 at high substrate temperature (about 777 °C). Scanning electron microscope pictures of the diamond particles show that the surfaces of synthetic diamond consist of rough-octahedral (111) faces and smooth-cubic (100) faces, which is cubo-octahedron. And also the (110) facets on the octahedral face are observed. The relat
EMGs are a natural means of HCI because the electrical activity induced by the human's arm muscle movements can be interpreted to used as computer's control commands. In This work, we present an on-line EMG-MOUSE system that controls movements of a cursor, which are interpretations of 6 pre-defined wrist motions: up, down, left, right, click, and rest. To emphasize a wearability, we designed the hardware in a way that electrodes are located on a circular armband, which wraps around the forearm.
Type-specific total viral load may be a powerful diagnostic marker for HSIL+ in HPV 16-, 18-, and 58-infected HSIL+ lesions. If demonstrated in all other high-risk HPV types, this method can lead to a paradigm shift in the strategy of equivocal cytologic abnormalities.
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