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이주희 교수

Joo Hee Lee

서울대학교 · 공학

연구실 소개

이주희 교수의 연구실은 신경퇴행성질환, 특히 알츠하이머병의 병태생리 기전을 해소하기 위한 자연물 기반 약물 개발과 신경세포 재생 가능성 탐색에 초점을 맞추고 있습니다. 또한, 갈락토스를 타가투오스로 전환하는 효소 및 비효소적 경로의 최적화를 통해 저칼로리 천연당 생산 기술을 개발하고 있으며, FDG PET/CT 영상 분석을 통한 자가면역질환인 IgG4 관련 질환의 조기 진단 기법도 연구하고 있습니다. 특히, 치아에서 유래한 줄기세포의 신경세포 분화 능력에 대한 기초 연구를 통해 신경질환 치료에 활용 가능한 새로운 세포 기반 전략을 모색하고 있습니다.

알츠하이머병태가투오스줄기세포FDG-PET/CT신경세포 분화

연구 현황

논문 수
293
총 인용 수
4,559
최근 5년 논문
63
주요 분야
공학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
63총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
588총합
20222023202420252026

주요 논문

15
1
리뷰|인용수 361·2008
Meta-analysis of clinical trials of probiotics for prevention and treatment of pediatric atopic dermatitis
Joo-Hee Lee, David Seto, Leonard Bielory
SJR Q1FWCI 70.2Journal of Allergy and Clinical ImmunologyOA
Food ScienceAgricultural and Biological Sciences
2
논문|인용수 103·2012
Effects of VEGF and FGF-2 on proliferation and differentiation of human periodontal ligament stem cells
Joo-Hee Lee, Soyoun Um, Jun‐Hyeog Jang, Byoung‐Moo Seo
SJR Q1FWCI 9.3Cell and Tissue Research
UrologyMedicine
3
논문|인용수 92·2012
Esophageal Diameter Is Decreased in Some Patients With Eosinophilic Esophagitis and Might Increase With Topical Corticosteroid Therapy
Joo-Hee Lee, James E. Huprich, Christine Kujath, Karthik Ravi, Felicity Enders, Thomas C. Smyrk, David A. Katzka, Nicholas J. Talley, Jeffrey A. Alexander
SJR Q1FWCI 10.6Clinical Gastroenterology and Hepatology
SurgeryMedicine
4
논문|인용수 77·2015
Aerodynamic characteristics of two-bladed H-Darrieus at various solidities and rotating speeds
Sungjun Joo, Heung-Soap Choi, Ju-Hee Lee
SJR Q1FWCI 183.4Energy
Aerospace EngineeringEngineering
5
논문|인용수 65·2021
Gender-based disparities in burn injuries, care and outcomes: A World Health Organization (WHO) Global Burn Registry cohort study
Kajal Mehta, Hana Arega, Natalie Smith, Kathleen Li, Emma Gause, Joo-Hee Lee, Barclay T. Stewart
SJR Q1FWCI 5.3The American Journal of SurgeryOA
EpidemiologyMedicine
6
리뷰|인용수 53·2011
Eosinophilic Gastrointestinal Disorders (EGID) with Peripheral Eosinophilia: A Retrospective Review at Mayo Clinic
Joo-Hee Lee, Ross Dierkhising, Tsung‐Teh Wu, Jeffrey A. Alexander, Catherine R. Weiler
SJR Q2FWCI 0.9Digestive Diseases and Sciences
SurgeryMedicine
7
논문|인용수 51·2016
Utility of FDG PET/CT for Differential Diagnosis of Patients Clinically Suspected of IgG4-Related Disease
Joo-Hee Lee, Seung Hyup Hyun, Seokhwi Kim, Duk‐Kyung Kim, Jong Kyun Lee, Seung Hwan Moon, Young Seok Cho, Yearn Seong Choe, Byung‐Tae Kim, Kyung-Han Lee
SJR Q2FWCI 5.4Clinical Nuclear Medicine

FDG PET/CT findings may have the capacity to potentially differentiate IgG4 RD from other diseases in clinically suspected patients.

RheumatologyMedicine
8
논문|인용수 46·2010
Influence of Wing Configurations on Aerodynamic Characteristics of Wings in Ground Effect
Ju-Hee Lee, Chang-Suk Han, Chang‐Hwan Bae
SJR Q1FWCI 75.5Journal of Aircraft

A numerical analysis is performed to investigate the aerodynamic characteristics and the static height stability of the endplate and the anhedral angle on an aspect-ratio-one wing-in-ground effect. The analysis shows that the ground effect increases the lift by the high pressure on the lower surface, reduces the drag, increases the suction on the upper surface, and considerably enhances the lift-drag ratio. The endplate, which prevents the high-pressure air from escaping out of the lower surface

Aerospace EngineeringEngineering
9
리뷰|인용수 40·2021
Natural Products Targeting Amyloid Beta in Alzheimer’s Disease
Joo-Hee Lee, Na-Hyun Ahn, Su-Bin Choi, Youngeun Kwon, Seung‐Hoon Yang
SJR Q1FWCI 2.4International Journal of Molecular SciencesOA

Alzheimer's disease (AD) is a neurodegenerative disease characterized by severe brain damage and dementia. There are currently few therapeutics to treat this disease, and they can only temporarily alleviate some of the symptoms. The pathogenesis of AD is mainly preceded by accumulation of abnormal amyloid beta (Aβ) aggregates, which are toxic to neurons. Therefore, modulation of the formation of these abnormal aggregates is strongly suggested as the most effective approach to treat AD. In partic

Molecular MedicineBiochemistry, Genetics and Molecular Biology
10
리뷰|인용수 39·2010
Complementary and Alternative Interventions in Atopic Dermatitis
Joo-Hee Lee, Leonard Bielory
SJR Q2FWCI 2.3Immunology and Allergy Clinics of North America
DermatologyMedicine
11
논문|인용수 26·2014
Neurogenic differentiation of human dental stem cells<i>in vitro</i>
Joo-Hee Lee, Soyoun Um, In‐Seok Song, Hui Young Kim, Byoung‐Moo Seo
SJR Q2FWCI 2.2Journal of the Korean Association of Oral and Maxillofacial SurgeonsOA

Human dental stem cells including DPSCs, PDLSCs, and SCAP may have neurogenic differentiation capability in vitro. The presented data support the use of human dental stem cells as a possible alternative source of stem cells for therapeutic utility in the treatment of neurological diseases.

GeneticsMedicine
12
논문|인용수 24·2018
Computational analysis of static height stability and aerodynamics of vehicles with a fuselage, wing and tail in ground effect
Ju-Hee Lee
SJR Q1FWCI 10.1Ocean Engineering
Aerospace EngineeringEngineering
13
리뷰|인용수 23·2023
Isomerization of Galactose to Tagatose: Recent Advances in Non-enzymatic Isomerization
Jikai Zhao, Zhuo Wang, Qing Jin, Danyi Feng, Ju-Hee Lee
SJR Q1FWCI 2.5Journal of Agricultural and Food Chemistry

The valorization of galactose derived from acid whey to low-calorie tagatose has gained increasing attention. Enzymatic isomerization is of great interest but faces several challenges, such as poor thermal stability of enzymes and a long processing time. In this work, non-enzymatic (supercritical fluids, triethylamine, arginine, boronate affinity, hydrotalcite, Sn-β zeolite, and calcium hydroxide) pathways for galactose to tagatose isomerization were critically discussed. Unfortunately, most of

Biomedical EngineeringEngineering
14
논문|인용수 19·2021
Prognostic Significance of Metabolic Parameters by 18F-FDG PET/CT in Thymic Epithelial Tumors
Joo-Hee Lee, Young Seok Cho, Young Tae Kim, Young Mog Shim, Kyung-Han Lee, Joon Young Choi
SJR Q1FWCI 1.4CancersOA

SUV<sub>avg</sub> and Masaoka stage are independent prognostic factors in thymic epithelial tumors.

NeurologyMedicine
15
논문|인용수 17·2019
Diagnostic accuracy of low-radiation coronary computed tomography angiography with low tube voltage and knowledge-based model reconstruction
Joo-Hee Lee, Tae Hoon Kim, Byoung Kwon Lee, Young Won Yoon, Hyuck Moon Kwon, Bum‐Kee Hong, Pil‐Ki Min, Eui‐Young Choi, Chi Suk Oh, Chul Hwan Park
SJR Q1FWCI 2.4Scientific ReportsOA

We aimed to evaluate the accuracy of coronary computed tomography angiography (CCTA) with a low-radiation protocol and iterative model reconstruction (IMR), in comparison with invasive coronary angiography (ICA). Sixty-one patients (45 males; mean age, 61.9 ± 9.2 years) with suspected coronary artery disease who underwent CCTA and ICA were retrospectively enrolled. CCTA was performed with low tube voltage (80 or 100 kVp), low tube current (100-200 mAs), prospective ECG triggering, and IMR using

Radiology, Nuclear Medicine and ImagingMedicine

대표 연구 분야

Aerospace EngineeringBiomedical EngineeringMolecular BiologyOcean EngineeringElectrical and Electronic EngineeringMechanical Engineering

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