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박준성 교수

Joon Seong Park

서울대학교 · 의학

연구실 소개

박준성 교수의 연구실은 주로 암 생물학과 외과 수술 후 관리 전략에 초점을 맞추고 있습니다. 특히 췌장암의 전이 및 복귀 메커니즘을 규명하고, LOXL2와 같은 생물학적 마커가 예후에 미치는 영향을 분석하는 데 주력하고 있습니다. 또한 병리학적 특성과 임상적 결과 간의 연관성을 규명함으로써, 개인화된 치료 전략 수립에 기여하고자 합니다. 수술 후 영양관리 및 합병증 예방 전략에 대해서도 임상적 연구를 진행하고 있습니다.

췌장암전이 예측LOXL2수술 후 영양예후 마커

연구 현황

논문 수
303
총 인용 수
5,374
최근 5년 논문
76
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
76총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
391총합
20222023202420252026

주요 논문

15
1
논문|인용수 227·2001
Role-based access control on the web
Joon Seong Park, Ravi Sandhu, Gail‐Joon Ahn
FWCI 73.2ACM Transactions on Information and System Security

Current approaches to access control on the Web servers do not scale to enterprise-wide systems because they are mostly based on individual user identities. Hence we were motivated by the need to manage and enforce the strong and efficient RBAC access control technology in large-scale Web environments. To satisfy this requirement, we identify two different architectures for RBAC on the Web, called user-pull and server-pull . To demonstrate feasibility, we implement each architecture by integrati

Sociology and Political ScienceSocial Sciences
2
논문|인용수 141·2009
Clinical validation and risk factors for delayed gastric emptying based on the International Study Group of Pancreatic Surgery (ISGPS) Classification
Joon Seong Park, Ho Kyoung Hwang, Jae Keun Kim, Sin Il Cho, Dong Sup Yoon, Woo Jung Lee, Sang Hoon
SJR Q1FWCI 3.4SurgeryOA
OncologyMedicine
3
논문|인용수 69·2007
What is the best treatment modality for adrenal metastasis from hepatocellular carcinoma?
Joon Seong Park, Dong Sup Yoon, Kyung Sik Kim, Jin Sub Choi, Woo Jung Lee, Sang Hoon, Byong Ro Kim
SJR Q1FWCI 3.2Journal of Surgical OncologyOA

We envisage increased benefit after adrenalectomy in terms of survival in patients with well controlled intrahepatic lesions at the time of adrenal metastasis and good general medical condition.

SurgeryMedicine
4
논문|인용수 68·2012
Postoperative Nutritional Effects of Early Enteral Feeding Compared with Total Parental Nutrition in Pancreaticoduodectomy Patients: A Prosepective, Randomized Study
Joon Seong Park, Hye-Kyung Chung, Ho Kyoung Hwang, Jae Keun Kim, Dong Sup Yoon
SJR Q2FWCI 2.1Journal of Korean Medical ScienceOA

The benefits of early enteral feeding (EEN) have been demonstrated in gastrointestinal surgery. But, the impact of EEN has not been elucidated yet. We assessed the postoperative nutritional status of patients who had undergone pancreaticoduodenectomy (PD) according to the postoperative nutritional method and compared the clinical outcomes of two methods. A prospective randomized trial was undertaken following PD. Patients were randomly divided into two groups; the EEN group received the postoper

OncologyMedicine
5
논문|인용수 67·2015
Use of TachoSil<sup>®</sup> patches to prevent pancreatic leaks after distal pancreatectomy: a prospective, multicenter, randomized controlled study
Joon Seong Park, Doo‐Ho Lee, Jin‐Young Jang, Youngmin Han, Dong Sup Yoon, Jae Keun Kim, Ho‐Seong Han, Yoo‐Seok Yoon, Dae Wook Hwang, Chang Moo Kang, Ho Kyoung Hwang, Woo Jung Lee
SJR Q1FWCI 3.2Journal of Hepato-Biliary-Pancreatic SciencesOA

This study showed that the TachoSil® patch did not reduce the incidence of POPF after distal pancreatectomy.

OncologyMedicine
6
논문|인용수 66·2007
Factors influencing recurrence after curative resection for ampulla of vater carcinoma
Joon Seong Park, Dong Sup Yoon, Kyung Sik Kim, Jin Sub Choi, Woo Jung Lee, Sang Hoon, Byong Ro Kim
SJR Q1FWCI 2.3Journal of Surgical OncologyOA

Lymph node metastasis is the most important risk factor for recurrence after a curative resection. Also, the fact that a higher probability of recurrence is anticipated in cases of ulcer formation and poorly differentiated tumors, there exists a need for a close-up follow-up program.

OncologyMedicine
7
논문|인용수 57·2016
Emerging role of LOXL2 in the promotion of pancreas cancer metastasis
Joon Seong Park, Ji-hae Lee, Yun Sun Lee, Jae Keun Kim, Seung Myung Dong, Dong Sup Yoon
SJR Q2FWCI 4.5OncotargetOA

Lysyl oxidase-like 2 (LOXL2) is associated with invasiveness and metastasis in cancer. We analyzed the prognostic impact of LOXL2 in pancreatic cancer patients and investigated the role of LOXL2 in pancreatic cancer cell lines. Immunohistochemical analysis was performed in samples from 80 patients and showed LOXL2 expression in 81.2% of patients with pancreatic cancer. Regarding recurrence patterns, LOXL2-positive tumors showed a significantly higher rate of distant recurrence. The 1-year and 3-

Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
논문|인용수 52·2006
Dual Inverter Strategy for High Speed Operation of HEV Permanent Magnet Synchronous Motor
Joon Seong Park, Kwanghee Nam
FWCI 1.9Conference record

Bi-directional buck-boost DC/DC converter is normally utilized for high speed operation of motors for hybrid electric vehicles (HEV). In this work, a dual inverter strategy is proposed for HEV motor with the purpose of accommodating high speed operation without increasing battery voltage. By setting the secondary inverter to take care of only reactive voltage component, the secondary inverter do not carry voltage source other than capacitor bank. DC link voltage regulation is achieved through th

Electrical and Electronic EngineeringEngineering
9
논문|인용수 45·2020
Cancer-initiating cells in human pancreatic cancer organoids are maintained by interactions with endothelial cells
Jae-Il Choi, Sung Ill Jang, Jaehyun Hong, Chul Hoon Kim, Soon Sung Kwon, Joon Seong Park, Jong‐Baeck Lim
SJR Q1FWCI 2.3Cancer LettersOA

Pancreatic ductal adenocarcinoma (PDAC) shows poor prognosis and high malignancy due to the presence of cancer-initiating cells (CICs) and characteristics of the tumor microenvironment (TME). Organoids are useful for studying PDAC, and establishing organoids is dependent on stem cell growth factors, including Wnt signaling. Herein, using a conventional organoid culture system, we demonstrated that CD44(+)CD24(+) and CD44(+)CD24(+)EpCAM(+) CICs were enriched >65% in a PDAC patient-derived organoi

OncologyMedicine
10
논문|인용수 42·2019
Big data and analysis of risk factors for gallbladder disease in the young generation of Korea
Hyung Sun Kim, Seong Kyung Cho, Changsoo Kim, Joon Seong Park
SJR Q1FWCI 4.4PLoS ONEOA

In this study, obesity-related factors (BMI, waist size, thigh circumference, and cholesterol, LDL, and HDL levels) correlated with GB disease in the young generation of Korea.

Pulmonary and Respiratory MedicineMedicine
11
논문|인용수 40·2014
The role of abdominal drainage to prevent of intra-abdominal complications after laparoscopic cholecystectomy for acute cholecystitis: prospective randomized trial
Joon Seong Park, Joo Hee Kim, Jae Keun Kim, Dong Sup Yoon
SJR Q1FWCI 3.4Surgical EndoscopyOA
Pulmonary and Respiratory MedicineMedicine
12
논문|인용수 36·2007
Actual Recurrence Patterns and Risk Factors Influencing Recurrence After Curative Resection with Stage II Gallbladder Carcinoma
Joon Seong Park, Dong Sup Yoon, Kyung Sik Kim, Jin Sub Choi, Woo Jung Lee, Sang Hoon, Byong Ro Kim
SJR Q1FWCI 1.5Journal of Gastrointestinal SurgeryOA
SurgeryMedicine
13
논문|인용수 35·2023
SLC38A5 Modulates Ferroptosis to Overcome Gemcitabine Resistance in Pancreatic Cancer
Myeong‐Jin Kim, Hyung Sun Kim, Hyung Sun Kim, Hyeon Woong Kang, Da Eun Lee, Woosol Chris Hong, Ju-Hyun Kim, Min‐Soo Kim, Jae‐Ho Cheong, Hyo Jung Kim, Hyo Jung Kim, Joon Seong Park
SJR Q1FWCI 9.0CellsOA

Pancreatic cancer is characterized by a poor prognosis, with its five-year survival rate lower than that of any other cancer type. Gemcitabine, a standard treatment for pancreatic cancer, often has poor outcomes for patients as a result of chemoresistance. Therefore, novel therapeutic targets must be identified to overcome gemcitabine resistance. Here, we found that SLC38A5, a glutamine transporter, is more highly overexpressed in gemcitabine-resistant patients than in gemcitabine-sensitive pati

Pulmonary and Respiratory MedicineMedicine
14
논문|인용수 34·2012
Current Status of Laparoscopic Liver Resection in Korea
Joon Seong Park, Ho‐Seong Han, Dae Wook Hwang, Yoo‐Seok Yoon, Jai Young Cho, Yang‐Seok Koh, Choon Hyuck David Kwon, Kyung Sik Kim, Sang Bum Kim, Young-Hoon Kim, Hyung‐Chul Kim, Chong Woo Chu
SJR Q2FWCI 2.2Journal of Korean Medical ScienceOA

Since laparoscopic liver resection was first introduced in 2001, Korean surgeons have chosen a laparoscopic procedure as one of the treatment options for benign or malignant liver disease. We distributed and analyzed a nationwide questionnaire to members of the Korean Laparoscopic Liver Surgery Study Group (KLLSG) in order to evaluate the current status of laparoscopic liver resection in Korea. Questionnaires were sent to 24 centers of KLLSG. The questionnaire consisted of operative procedure, h

HepatologyMedicine
15
논문|인용수 30·2011
Wireless dry EEG for drowsiness detection
Joon Seong Park, Ling Xu, Vishnu Sridhar, Miaofang Chi, Gert Cauwenberghs
FWCI 0.4

Fatigue is a well recognized safety concern for drivers and other industrial workers who must stay alert and attentive for long periods of time. Currently, drowsiness detectors using EEG technology exist but are cumbersome and unreliable. The large number of standard EEG channels requires extensive wiring, while the conventional wet electrodes cause discomfort in long-term monitoring. We propose a simple and cheap one-channel drowsiness detection technology suitable for detecting drowsiness in a

Cognitive NeuroscienceNeuroscience

대표 연구 분야

OncologySurgeryMolecular BiologyPulmonary and Respiratory MedicineInformation SystemsHepatology

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