박준범 교수
Junboum Park
서울대학교 · 환경과학
연구실 소개
박준범 교수의 연구실은 주로 생체재료 및 나노소재를 기반으로 한 의료 및 환경 분야의 혁신적 연구를 수행하고 있습니다. 특히 구강 조직에서 유래한 간엽줄기세포의 특성 규명과 조직공학적 응용 가능성을 탐색하며, 나노튜브 및 그래핀 기반 나노소재의 제어된 성장 기술 개발에도 주력하고 있습니다. 또한, 환경 오염 저감을 위한 오yster shell 파우더를 이용한 중금속 제거 기술과 패션마스크에서 유출되는 마이크로플라스틱의 환경 영향 평가 등 실생활 문제 해결을 위한 다학제적 연구를 전개하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15In conclusion, we isolated and characterized stem cells from human gingival connective tissue with modified protocol. GMSCs showed multipotency with high proliferation and characteristics of mesenchymal stem cells. GMSCs are promising sources for tissue engineering and may be obtained during routine procedures under local anesthesia. Further research is needed to evaluate the potential of GSMCs' proliferation and cryopreservation.
Our results suggest that, unlike nucleus pulposus cells, anulus fibrosus cells are Fas Type-I cells, which undergo apoptosis through the death-inducing signaling complex. We also found that apoptosis of intervertebral disc cells can be attenuated by caspase inhibitors.
Single-use disposable facemasks have been used as a preventive measure against the ongoing COVID-19 pandemic. However, many researchers have found evidence that these facemasks are being dumped into lakes, rivers, and open garbage dumps. Facemasks have the potential of releasing microplastic fibers into the environment; a phenomenon that has been poorly investigated. Moreover, microplastic fibers composed of plastics have the potential of affecting the flora and fauna of many ecosystems. In this
Urease is an important virulence factor of pathogenicity of gastric Helicobacter pylori. The inhibition of H. pylori urease by the novel proton pump inhibitor, rabeprazole, was investigated kinetically. It was found to act as an irreversible noncompetitive inhibitor of the enzyme. The inhibitory potency of rabeprazole was dependent on the pH of reaction mixture and its Ki values were 0.14 microM (pH 5.0), 0.34 microM (pH 7.0) and 6.10 microM (pH 8.5). Progressive inactivation of urease by rabepr
Oyster shell powder is a potential adsorbent material that can be used to control pollution in groundwater. The current research objective is to evaluate the heavy metal ion adsorption properties by oyster shell powder in an aqueous solution. Three kinds of heavy metals (copper, cadmium, and lead) were adsorbed using oyster shell powder from aqueous solution. The effects of different temperatures, contact times, pH values, and initial concentrations were examined in order to optimize the conditi
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