이규언 교수
Lee, Kyu Eun
서울대학교 외과학교실 · 의학
연구실 소개
이 교수의 연구실은 로봇 및 에너지 수술 기술을 중심으로 최신 내 endoscopic 및 로봇 수술의 정밀성과 안정성을 높이기 위한 연구를 수행하고 있습니다. 특히 수술 중 외과의사의 운동 패턴을 정량적으로 평가할 수 있는 딥러닝 기반의 수술 기기 추적 알고리즘 개발로 수술 기술 평가의 객관화를 도모하고 있으며, 갑상선 및 부갑상선 수술에서 미세외과적 접근의 임상적 유용성과 미용적 결과를 최적화하는 데 초점을 맞추고 있습니다. 또한 갑상선암의 분자생물학적 특성과 예후 인자에 대한 분석을 통해 정밀의료 기반의 진단 및 치료 전략 개발에도 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Follicular thyroid carcinoma (FTC) and benign follicular adenoma (FA) are indistinguishable by preoperative diagnosis due to their similar histological features. Here we report the first RNA sequencing study of these tumors, with data for 30 minimally invasive FTCs (miFTCs) and 25 FAs. We also compared 77 classical papillary thyroid carcinomas (cPTCs) and 48 follicular variant of PTCs (FVPTCs) to observe the differences in their molecular properties. Mutations in H/K/NRAS, DICER1, EIF1AX, IDH1,
Robotic endoscopic thyroidectomy using the BABA technique is a feasible procedure and can be performed safely. It provides an excellent operative field view enabling easy identification of vital structures. It also gives the desired cosmetic results and minimal postoperative pain similar to conventional endoscopic thyroid surgery using the BABA technique.
PAA endoscopic neck surgery is a feasible method for thyroid and parathyroid surgery that permits good operative visualization and has minimal adverse effects and excellent cosmetic outcomes.
As the number of robotic surgery procedures has increased, so has the importance of evaluating surgical skills in these techniques. It is difficult, however, to automatically and quantitatively evaluate surgical skills during robotic surgery, as these skills are primarily associated with the movement of surgical instruments. This study proposes a deep learning-based surgical instrument tracking algorithm to evaluate surgeons' skills in performing procedures by robotic surgery. This method overca
The expression of p53 and nm23 seems to be related with poor prognosis of gastric cancer patients who have undergone gastrectomy. However, the prognostic significance was not revealed by a multivariate analysis.
BABA RoT yields good postoperative outcomes. With excellent cosmetic outcomes, this technique may be a suitable alternative for patients with thyroid diseases.
4D CT proved helpful in localizing target parathyroid glands of primary HPT that were missed by traditional imaging.
The microfluidic system, for the first time, was successfully applied to human clinical tissue samples and histopathological diagnosis was realized for breast cancers. Our results showing substantial agreement indicate that several cancer-related proteins can be simultaneously investigated on a single tumor section, giving clear advantages and technical advances over standard immunohistochemical method. This novel concept will enable histopathological diagnosis using numerous specific biomarkers
Background. Laparoscopic lateral transperitoneal adrenalectomy (LTA) has been the standard method for resecting benign adrenal gland tumors. Recently, however, laparoscopic posterior retroperitoneal adrenalectomy (PRA) has been more popular as an alternative method. This systematic review evaluates current evidence on adrenalectomy techniques, comparing laparoscopic LTA with PRA and laparoscopic adrenalectomy with robotic adrenalectomy. Methods. PubMed, Embase, and ISI Web of Knowledge databases
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