名古屋大学 · 医学
Masaaki Machino教授の研究室は、頸椎症性脊髄症や頸椎脊髄損傷の病態解明と、その治療成績の向上を目的とした臨床的・画像診断的研究を主軸としています。特に、頸椎の sagittal alignment や運動域(ROM)の維持、MRI所見と神経症状の関連、糖尿病が脊柱管形成術の予後に与える影響など、高齢者や合併症を有する患者における治療意思決定の根拠を提供する研究が進んでいます。また、画像診断技術の応用を活かした客観的評価手法の開発にも注力しています。
Figures are computed from collected data and may differ slightly.
Sagittal alignment was slightly changed, with only a 1.8° increase in lordosis. The ROM of the cervical spine was preserved by 87.9%. This preservation of alignment and ROM might be attributable to improvements including early removal of the cervical orthosis, postoperative neck exercises, and some surgical modifications.
Age-related and degenerative changes in the cervical spine, alignment, and ROM in each decade of life were established between CSM patients and asymptomatic subjects.
In Brief Study Design. This is a prospective imaging study of adult patients with cervical spinal cord injury without radiographic abnormality (SCIWORA). Objective. The purpose of this study was to investigate the occurrence rate of intramedullary high-signal intensity (increased signal intensity [ISI]) and prevertebral hyperintensity (PVH) in patients with SCIWORA, and examine their relationship to symptom severity and surgical outcome. Summary of Background Data. SCIWORA is accompanied by the
Diabetes with advanced age and long-term cervical spondylotic myelopathy symptoms adversely affected cervical laminoplasty outcomes. High preoperative glycated hemoglobin levels and long-term diabetes are risk factors for poor cervical laminoplasty outcomes in patients with diabetes and cervical spondylotic myelopathy.
Pre- and postoperative JOA scores were low in elderly patients. However, the achieved JOA score was almost similar among the 3 groups. Thus, elderly patients could obtain reasonable recovery after cervical laminoplasty.
In Brief The dural sac and spinal cord cross-sectional area during flexion and extension in patients with cervical spondylotic myelopathy were measured using multidetector-row computed tomography after myelography. The average dural sac and spinal cord cross-sectional area were less during extension than during fl exion from the C3–C4 to C7–T1 disc levels.
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TTIF provides for safe interbody fusion and 270 degrees of decompression using a single posterior approach. TTIF is a useful method for reconstructing thoracic spine lesions associated with neurologic deficits.
Modified double-door laminoplasty is a safe, reliable, and effective procedure for patients with CSM.
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The presence of PLC injury significantly influenced the severity of damage. In management of thoracic lumbar burst fractures, evaluation of PLC injury is important to accurately assess the severity of damage.
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