김민정 교수

Robot-assisted surgery in rectal cancer showed TME quality comparable with that of laparoscopic surgery, and it demonstrated similar postoperative morbidity, bowel function recovery, and quality of life.

Two new coumarin derivatives displayed highly selective “Off-On” fluorescence changes with pyrophosphate between various anions including ATP, ADP, AMP and inorganic phosphate in 100% aqueous solution.

Since dogs are part of many peoples' lives, research and industry related to their health and longevity are becoming a rising topic. Although gut microbiota (GM) is a key contributor to host health, limited information is available for canines. Therefore, this study characterized GM according to individual signatures (e.g., breed, age, and body condition score-BCS) of dogs living in the same environment. Fresh fecal samples from 96 healthy dogs were analyzed by sequencing the V3-V4 region of the

A history of heavy smoking (more than 40 pack-years) is an independently significant risk factor for anastomotic complications after low anterior resection in rectal cancer patients.

Drug-induced cardiotoxicity or cytotoxicity followed by cell death in cardiac muscle is one of the major concerns in drug development. Herein, we report a high-content quantitative multicolor single cell imaging tool for automatic screening of drug-induced cardiotoxicity in an intact cell. A tunable multicolor imaging system coupled with a miniaturized sample platform was destined to elucidate drug-induced cardiotoxicity via simultaneous quantitative monitoring of intracellular sodium ion concen

To identify low anterior resection syndrome (LARS) patterns and their associations with risk factors and quality of life (QOL). This cross-sectional study analyzed patients who underwent restorative anterior resection for left-sided colorectal cancer at Seoul National University Hospital, Seoul, Republic of Korea. We administered LARS questionnaires to assess bowel dysfunction and quality of life between April 2017 and November 2019. LARS patterns were classified based on factor analyses. Variab

외환위기 이후 경쟁이 심화되면서 일자리의 상당수가 비정규직 근로자로 채워지고 있다. 직업안정성의 악화는 소득 안정성의 악화로 이어져 고용지위에 관계없이 모든 임금 근로자의 가계재무관리에 위험요소로 작용한다. 직업안정성은 개인의 장기적․단기적 고용상태에 의한 것으로서 위험감수성향에 영향을 미치는 심리적 불안정의 가능성을 내포하고 있다. 이에 본 연구는 객관적인 직업안정성과 주관적인 위험감수성향에 따라 소비자의 포트폴리오에 차이가 있을 것으로 가정하고, 직업안정성에 따른 소비자의 위험감수 성향에 차이가 있는지를 파악하고, 직업안정성의 수준과 위험감수성향을 바탕으로 소비자를 네 집단으로 분류하였다. 연구결과, 직업안정성이 높은 집단은 상대적으로 다양한 가계재무 포트폴리오를 구성하고 있음을 알 수 있었으며, 직업안정성이 낮은 집단은 주식․채권․신탁자산의 보유율과 총 자산 대비 비중이 낮았다. 따라서 직업안정성이 낮은 집단의 임금 근로자를 대상으로 재무 교육을 실시함으로써 소비자 포트폴리오를

Extracellular vesicles (EVs) mediated intracellular communication plays an imperative role in the proper completion of different physiological events. Most of the bio-fluids are enriched with several subpopulations of EVs including exosomes and microvesicles (MVs), with the capacity of transferring different functional molecules (lipids, proteins, and nucleic acids) to target cells. Recipient cells upon receiving the signal molecules undergo different changes that positively affect the structura

Cryopreservation procedures negatively affect the quality traits of sperm, causing certain changes at structural and molecular levels due to thermal, mechanical, osmotic, and oxidative damage. The objective of this study was to examine the potential of canine adipose-derived mesenchymal stem cells (Ad-MSCs) for providing protection to the dog sperm against cryo-damage. Canine Ad-MSCs were selected on the basis of the significantly higher gene expression for different proteins actively involved i

The high separation efficiency of particles and cells can be realized by exploiting a facile two step label free technique that consists of elasto-inertial focusing and magnetophoresis.

Hyaluronic acid synthase 2 (HAS2) is suggested to play a critical role in malignancy and is abnormally expressed in many carcinomas. However, its role in colorectal cancer (CRC) malignancy and specific signaling mechanisms remain obscure. Here, we report that HAS2 was markedly increased in both CRC tissue and malignant CRC cell lines. Depletion of HAS2 in HCT116 and DLD1 cells, which express high levels of HAS2, critically increased sensitivity of radiation/oxaliplatin-mediated apoptotic cell de