강민규 교수
Minkyu Kang
서울대학교 · 의학
연구실 소개
강민규 교수의 연구실은 임상 및 생물정보학적 접근을 융합한 의학 연구를 중심으로, 알레르기성 질환의 예측 및 치료 전략 개발에 초점을 맞추고 있습니다. 특히 알레르기성 비염의 온라인 검색 트렌드 분석, 프로바이오틱스를 활용한 치료 효과 평가, 만성기침의 유병 양상 분석 등 대규모 인구자료를 기반으로 한 역학 연구가 두드러집니다. 또한 생체재료의 물리적 거동을 해석하는 이론 모델링을 통해 의료 기기 및 치료 기술의 기초를 다지고 있습니다.
연구 현황
연구 성과 추이
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주요 논문
15The findings of our meta-analysis suggest that the success rate and postoperative complication rate for endoscopic DCR is not influenced by the use of silicone intubation during the procedure.
Google Trends (GT) is a Web-based surveillance tool used to explore the searching trends of specific queries on Google. Recent studies have suggested the utility of GT in predicting outbreaks of influenza and other diseases. However, this utility has not been thoroughly evaluated for allergic diseases. Therefore, we investigated the utility of GT for predicting the epidemiology of allergic rhinitis. In the USA, GT for allergic rhinitis showed repetitive seasonality that peaked in late April and
Although several recent studies reported that probiotics might be beneficial for allergic rhinitis (AR), the effect of probiotics on AR is not consistent and have not been reproduced between studies. We aimed to determine the efficacy and safety of probiotic NVP-1703, a mixture of <i>Bifidobacterium longum</i> and <i>Lactobacillus plantarum</i>, in subjects with perennial AR. Adult subjects with perennial AR received either NVP-1703 (<i>n</i> = 47) or placebo (<i>n</i> = 48) for four weeks. Tota
Swell-induced surface instability has been observed experimentally in rubbers and gels. Here we present a theoretical model that predicts the critical condition along with a characteristic wavelength for swell-induced surface instability in substrate-confined hydrogel layers. The effect of surface tension is found to be critical in suppressing short-wavelength modes of instability, while the substrate confinement suppresses long-wavelength modes. Together, an intermediate wavelength is selected
Cough is frequently self-limiting, but may persist longer in certain individuals. Most of previous studies on the epidemiology of chronic cough have only measured period prevalence, and thus have afforded limited information on the burden and natural course. We aimed to investigate the epidemiology of chronic cough by using a point prevalence measure in a large-scale general population.We analyzed cross-sectional data collected from 18,071 adults who participated in the Korean National Health an
The prevalence of nonalcoholic fatty liver in IBD patients was 11.1%, and sarcopenia was an independent risk factor.
Adverse drug events are significant causes of emergency department visits. Systematic evaluation of adverse drug events leading to emergency department visits by age is lacking. This multicenter retrospective observational study evaluated the prevalence and features of adverse drug event-related emergency department visits across ages. We reviewed emergency department medical records obtained from three university hospitals between July 2014 and December 2014. The proportion of adverse drug even
AF is independently associated with advanced liver fibrosis in patients with NAFLD.
Abstract Background and Aim Although low skeletal muscle mass (LSMM) is known to increase the risk of non‐alcoholic fatty liver disease (NAFLD), limited reports have described the relationship between LSMM and advanced fibrosis. Here, we investigated the association between LSMM and advanced liver fibrosis in NAFLD patients. Methods Fatty liver was diagnosed using ultrasound, and appendicular skeletal muscle mass (ASM) was measured using bioelectrical impedance analysis. LSMM was defined in two
HT seemed to increase the response of both primary tumour and lymph nodes to preoperative radiochemotherapy in patients with locally advanced rectal cancer. The relationship between increased response by HT and survival should be confirmed by a large prospective randomised trial.
The present analysis suggests a panel of 10 most common inhalant allergens in Korean adult patients with suspected respiratory allergies, which explained 90% of inhalant allergen sensitization. This panel can be utilized as a practical and convenient tool for primary practice and epidemiological surveys of respiratory allergic diseases.
Aims and Background We report the results of intensity-modulated radiotherapy for patients with advanced hepatocellular carcinoma who were not candidate for local ablative therapies, transarterial chemoembolization or hepatic arterial infusion chemotherapy. Methods and Study Design Between 2003 and 2008, 27 patients were treated with high-dose radiotherapy (median dose, 50.4 Gy). The equivalent sphere size of tumors was 11.4 ± 2.6 cm. Nineteen and 8 patients were Child-Pugh class A and B, respec
The number of SCAR ICSRs has increased rapidly with recent active pharmacovigilance programs in Korea. Allopurinol and antiepileptics are the most common individual and categorical causative agents, respectively.
Sarcopenia and nonalcoholic fatty liver disease (NAFLD) are associated with subclinical atherosclerosis. We aimed to investigate the association between low skeletal muscle mass (LSMM) and subclinical atherosclerosis in patients with NAFLD. A total of 683 patients with ultrasound-confirmed NAFLD who underwent carotid ultrasonography were enrolled retrospectively. The appendicular skeletal muscle mass divided by the body mass index was used to define LSMM. Using carotid ultrasound, increased caro
We evaluated the association between body mass index (BMI) and the prevalence of asthma. Using data from the 2015 Korean Community Health Survey, 214,971 participants aged between 19 and 106 years were included in this study. Asthma was defined based on the self-report of physician diagnosis. BMI was classified as underweight (<18.5 kg/m<sup>2</sup>), normal weight (18.5 kg/m<sup>2</sup>≤BMI<23.0 kg/m<sup>2</sup>), overweight (23.0 kg/m<sup>2</sup>≤ BMI<27.4 kg/m<sup>2</sup>), and obese (≥27.5 k
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