오승원 교수
Seung-Won Oh
서울대학교 · 의학
연구실 소개
오승원 교수의 연구실은 대사질환, 특히 비알코올성 간지방증후군(NAFLD)과 대사증후군(MetS)의 발병 기전과 예후 요소를 중심으로 연구를 진행하고 있습니다. 유전적 요인, 생활습관, 약물의 심혈관계 영향까지 포괄적인 접근을 통해 대사질환의 조기 진단 및 개인 맞춤형 치료 전략 개발을 목표로 하고 있습니다. 특히 항당뇨제의 심혈관계 안전성과 우울증 치료제가 심장질환에 미치는 영향에 대한 메타분석을 통해 임상적 지침 마련에 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15NAFLD was associated with risk for components of MetS, and the association was stronger in non-obese than in obese individuals, especially in women. Therefore, NAFLD should be considered a meaningful predictor of metabolic diseases in the non-obese population.
Metabolic syndrome (MetS) which is caused by obesity and insulin resistance, is well known for its predictive capability for the risk of type 2 diabetes mellitus and cardiovascular disease. The development of MetS is associated with multiple genetic factors, environmental factors and lifestyle. We performed a genome-wide association study to identify single-nucleotide polymorphism (SNP) related to MetS in large Korean population based samples of 1,362 subjects with MetS and 6,061 controls using
In the Guidance for Industry from the Food and Drug Administration in 2008, excess cardiovascular risk should be ruled out in trials of all new antidiabetic drugs; however, relatively few studies have focused on cardiovascular safety with antidiabetic drug use. We aimed to examine mortality and cardiovascular risk using a network meta-analysis. We searched the Medline, Embase, Cochrane, and ClinicalTrials.gov registry databases in March 2016 to identify randomized controlled trials reporting car
This meta-analysis of observational studies in subjects with no history of CHD suggests that neither selective serotonin reuptake inhibitor nor tricyclic antidepressant use is associated with an increased risk of CHD.
Overall, the findings of this meta-analysis do not support the hypothesis that there is a link between HT use and lung cancer risk. Our findings should be evaluated in further prospective cohort studies.
All breast cancers in lactating females in this study were observed on breast MR imaging despite the moderate-to-marked background parenchymal enhancement of lactating mammary tissue. Advances in knowledge: MR imaging can be used in the evaluation of disease extent and assessment of therapeutic response after neoadjuvant chemotherapy of breast cancer diagnosed during lactation.
2) Objectives: This study sought to provide evidence for the relationship between health risks and self- reported absenteeism and presenteeism. Methods: A cross-sectional analysis of 496 employees of an electric company was conducted. Participants responded to a self-questionnaire including the assessment of 7 health risks (obesity, current smoking, problem drinking, lack of exercise, chronic disease, depressive mood, high stress) and the Work Productivity and Activity Impairment - General Healt
The incidence of colorectal cancer is rapidly increasing in South Korea. It is important to clarify the association between colorectal cancer and diet, being one of the main modifiable risk factors, as such studies in the Korean population are lacking.A cross-sectional study was performed using data from participants who had undergone a screening colonoscopy and a nutritional assessment during a routine health check-up from January 2008 to December 2011. Dietary intake data were derived from 1-d
In this cohort study of multiethnic US adults, LCD score was not associated with mortality in the whole population. However, moderate carbohydrate intake was associated with a lower risk of mortality among Hispanic participants. These findings suggest that the association between carbohydrate intake and mortality may differ according to race and ethnicity. Dietary guidelines considering these differences may be necessary.
Medicine is highly professional and its academic development is fast; therefore, information asymmetry between suppliers and consumers is severe.It is difficult for patients to de-
Visceral adipose tissue was a significant risk factor for subsequent chronic kidney disease progression, and the association was identified only in the normal weight group. Normal-weight central obesity was associated with excess risk of chronic kidney disease, similar to the risk in the group with obesity and central obesity.
See the article "Short-Term Success Rates of Smoking Cessation Support Programs and Factors Predicting Smoking Relapse: Using Data from a Smoking Cessation Clinic in a Hospital" on page 373.
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