Skip to main content

이승현 교수

Seunghyun Lee

서울대학교 · 의학

연구실 소개

이승현 교수의 연구실은 생물의학적 질병 모델과 신진대사, 신경영상 기술, 병원체 진단, 그리고 나노전자 소자의 기초 연구를 융합한 다학제적 연구를 수행하고 있습니다. 특히 건성 안증 환자 모델의 회복 메커니즘, 고압을 이용한 단백질 재조립, 뇌혈류 측정을 위한 MRI 기반 영상 기술, 희귀 감염병의 신속 진단 기법 개발, 그리고 전하에 민감한 나노소재 기반의 이온 트랜지스터 설계 등 다양한 분야에서 혁신적인 기술 개발을 이끌고 있습니다. 연구는 임상적 응용과 기초 생물학적 원리의 통합을 목표로 하며, 의학 및 생명공학 분야의 실질적 발전에 기여하고 있습니다.

건성 안증단백질 재조립뇌혈류 영상병원체 진단이온 트랜지스터

연구 현황

논문 수
341
총 인용 수
3,132
최근 5년 논문
128
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
128총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
201총합
20222023202420252026

주요 논문

15
1
논문|인용수 104·2014
Evaluation of the microenvironmental heterogeneity in high-grade gliomas with IDH1/2 gene mutation using histogram analysis of diffusion-weighted imaging and dynamic-susceptibility contrast perfusion imaging
Seunghyun Lee, Seung Hong Choi, Inseon Ryoo, Tae Jin Yoon, Tae Min Kim, Se‐Hoon Lee, Chul‐Kee Park, Ji‐hoon Kim, Chul‐Ho Sohn, Sung‐Hye Park, Il Han Kim
SJR Q1FWCI 3.6Journal of Neuro-Oncology
GeneticsMedicine
2
논문|인용수 63·2018
Monitoring Cerebral Perfusion Changes after Revascularization in Patients with Moyamoya Disease by Using Arterial Spin-labeling MR Imaging
Seunghyun Lee, Tae Jin Yun, Roh‐Eul Yoo, Byung‐Woo Yoon, Koung Mi Kang, Seung Hong Choi, Ji‐hoon Kim, Jeong Eun Kim, Chul‐Ho Sohn, Moon Hee Han
SJR Q1FWCI 6.3Radiology

Purpose To determine whether arterial spin-labeling (ASL) magnetic resonance (MR) imaging could be used to identify changes in cerebral blood flow (CBF), collateral blood flow, and anastomosis site patency after revascularization in patients with moyamoya disease. Materials and Methods This retrospective study was conducted in 145 patients with moyamoya disease who underwent middle cerebral artery (MCA)-superficial temporal artery anastomosis. Preoperative, early postoperative, and late postoper

RheumatologyMedicine
3
논문|인용수 48·2020
Noise reduction approach in pediatric abdominal CT combining deep learning and dual-energy technique
Seunghyun Lee, Young Hun Choi, Yeon Jin Cho, Seul Bi Lee, Jung‐Eun Cheon, Woo Sun Kim, Chulkyun Ahn, Jong Hyo Kim
SJR Q1FWCI 2.5European Radiology
Biomedical EngineeringEngineering
4
논문|인용수 45·2017
Review of the subgenus Aethina Erichson s. str. (Coleoptera: Nitidulidae: Nitidulinae) in Korea, reporting recent invasion of small hive beetle, Aethina tumida
Seunghyun Lee, Seunghyun Lee, Ki–Jeong Hong, Yun Sang Cho, Yong Soo Choi, Mi-Sun Yoo, Seunghwan Lee, Seunghwan Lee
SJR Q2FWCI 5.0Journal of Asia-Pacific Entomology
Insect ScienceAgricultural and Biological Sciences
5
논문|인용수 43·2014
Sub-10 nm transparent all-around-gated ambipolar ionic field effect transistor
Seunghyun Lee, Hyomin Lee, Tianguang Jin, Sungmin Park, Byung Jun Yoon, Gun Yong Sung, Ki‐Bum Kim, Sung Jae Kim
SJR Q1FWCI 4.3NanoscaleOA

In this paper, we developed a versatile ionic field effect transistor (IFET) which has an ambipolar function for manipulating molecules regardless of their polarity and can be operated at a wide range of electrolytic concentrations (10(-5) M-1 M). The IFET has circular nanochannels radially covered by gate electrodes, called "all-around-gate", with an aluminum oxide (Al2O3) oxide layer of a near-zero surface charge. Experimental and numerical validations were conducted for characterizing the IFE

Electrical and Electronic EngineeringEngineering
6
논문|인용수 43·2011
Outcome of laparoscopic rectopexy versus perineal rectosigmoidectomy for full-thickness rectal prolapse in elderly patients
Seunghyun Lee, Paryush Lakhtaria, Jorge Canedo, Yoon Suk Lee, Steven D. Wexner
SJR Q1FWCI 3.7Surgical Endoscopy
RheumatologyMedicine
7
논문|인용수 37·2017
Review of the subgenus Aethina Erichson s. str. (Coleoptera: Nitidulidae: Nitidulinae) in Korea, reporting recent invasion of small hive beetle, Aethina tumida
이승현, 홍기정, 조윤상, 최용수, 유미선, 이승환

Four species of the subgenus Aethina Erichson sensu stricto are recognized in Korea, including two species newto Korea: Aethina (s.str) aeneipennis, and the small hive beetle (SHB), A. (s.str) tumida. This is the first report of the small hive beetle in the Far Eastern Asia,which has been recently spreading worldwide, causing big economic loss in beekeeping industry. Comments on external and genital structures, brief biology, illustrations of the genitalia of both male and female, and a key to s

8
논문|인용수 33·2015
Study on the Correlation between the Heat Release Rate and Vibrations from a Diesel Engine Block
Seunghyun Lee, Yoonwoo Lee, Sungmoon Lee, Han Ho Song, Kyoungdoug Min, Hoimyung Choi
FWCI 2.1SAE technical papers on CD-ROM/SAE technical paper series

<div class="section abstract"><div class="htmlview paragraph">In this study, a correlation between the maximum heat release rate and vibrations from a diesel engine block was derived, and a methodology to determine the maximum heat release rate is presented. To investigate and analyze the correlation, an engine test and an actual road vehicle test were performed using a 1.6-L diesel engine. By varying the engine speed, load and main injection timing, the vibration signals from the en

Fluid Flow and Transfer ProcessesChemical Engineering
9
논문|인용수 32·2020
Evolution of feeding habits of sap beetles (Coleoptera: Nitidulidae) and placement of Calonecrinae
Min Hyeuk Lee, Seunghyun Lee, Seunghyun Lee, Richard A. B. Leschen, Seunghwan Lee, Seunghwan Lee
SJR Q1FWCI 4.2Systematic Entomology

Abstract Nitidulidae includes some 4500 species under 350 genera in ten subfamilies, making it the most species‐rich family in Cucujoidea. In this study, we present a phylogeny of the family based on five gene regions (COI, 28s, CAD, H3, Wingless) for 73 ingroup taxa representing nine of the ten currently recognized subfamilies of Nitidulidae, including the enigmatic subfamily Calonecrinae. Our results are consistent with a prior molecular study that recovered (i) paraphyletic Nitidulinae with t

Ecology, Evolution, Behavior and SystematicsAgricultural and Biological Sciences
10
논문|인용수 27·2019
Multigene phylogeny uncovers oviposition-related evolutionary history of Cerambycinae (Coleoptera: Cerambycidae)
Seunghyun Lee, Seunghwan Lee
SJR Q1FWCI 2.1Molecular Phylogenetics and Evolution
EcologyEnvironmental Science
11
논문|인용수 27·2021
Deep Learning-Based Image Conversion Improves the Reproducibility of Computed Tomography Radiomics Features
Seul Bi Lee, Yeon Jin Cho, Youngtaek Hong, Dawun Jeong, Jina Lee, Soohyun Kim, Seunghyun Lee, Young Hun Choi
SJR Q1FWCI 3.5Investigative RadiologyOA

Our study demonstrated that a deep learning model for image conversion can improve the reproducibility of radiomics features across various CT protocols, reconstruction kernels, and CT scanners.

Radiology, Nuclear Medicine and ImagingMedicine
12
논문|인용수 25·2020
Population genetic structure of Anoplophora glabripennis in South Korea: Invasive populations in the native range?
Seunghyun Lee, Yerim Lee, Seunghwan Lee
SJR Q1FWCI 1.9Journal of Pest Science
EcologyEnvironmental Science
13
논문|인용수 21·2021
The usefulness of noninvasive liver stiffness assessment using shear-wave elastography for predicting liver fibrosis in children
Seunghyun Lee, Young Hun Choi, Yeon Jin Cho, Seul Bi Lee, Jung‐Eun Cheon, Woo Sun Kim, Jae Sung Ko, Jaemoon Koh, Gyeong Hoon Kang
SJR Q2FWCI 2.4BMC Medical ImagingOA

The liver stiffness values on 2D-SWE can be affected by both fibrosis and necroinflammatory grade and can provide excellent diagnostic performance in evaluating the fibrosis stage in various pediatric liver diseases. However, clinicians should be mindful of potential confounders, such as necroinflammatory activity or transaminase level, when performing 2D-SWE measurements for liver fibrosis staging.

EpidemiologyMedicine
14
논문|인용수 20·2020
Haploinsufficiency of <i>Cyfip2</i> Causes <scp>Lithium‐Responsive</scp> Prefrontal Dysfunction
Seunghyun Lee, Seunghyun Lee, Yinhua Zhang, Jin-A Park, Bowon Kim, Yangsik Kim, Sanghoon Lee, Sanghoon Lee, Gyu Hyun Kim, Yang Hoon Huh, Bokyoung Lee, Yoonhee Kim
SJR Q1FWCI 1.6Annals of Neurology

These results suggest that L5-specific prefrontal dysfunction, especially hyperexcitability, underlies both the pathophysiology and the lithium-mediated amelioration of neurobehavioral phenotypes in adult Cyfip2<sup>+/-</sup> mice, which can be implicated in CYFIP2-associated brain disorders. ANN NEUROL 2020;88:526-543.

GeneticsBiochemistry, Genetics and Molecular Biology
15
논문|인용수 20·2019
Computerized texture analysis of pulmonary nodules in pediatric patients with osteosarcoma: Differentiation of pulmonary metastases from non-metastatic nodules
Yeon Jin Cho, Woo Sun Kim, Young Hun Choi, Ji Young Ha, Seunghyun Lee, Sang Joon Park, Jung‐Eun Cheon, Hyoung Jin Kang, Hee Young Shin, In-One Kim
SJR Q1FWCI 2.0PLoS ONEOA

Pulmonary metastases from osteosarcoma could be differentiated from non-metastases by using computerized texture analysis. Higher mean attenuation and larger diameter were significant predictors for pulmonary metastases, while higher mean attenuation was a significant predictor for small non-calcified pulmonary metastases.

Radiology, Nuclear Medicine and ImagingMedicine

대표 연구 분야

Radiology, Nuclear Medicine and ImagingSurgeryRheumatologyCivil and Structural EngineeringBiomedical EngineeringFluid Flow and Transfer Processes

이승현 교수의 연구를 Nubint에서 더 깊이 살펴보세요

이 연구실의 논문을 앱에서 열어 AI와 함께 읽고, 핵심을 요약하고, 내 글에 인용하세요.