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이수현 교수

Sue-Hyun Lee

서울대학교 · 의학

연구실 소개

이수현 교수의 연구실은 기억의 재편성 과정에서 단백질 분해와 재형성의 역할을 중심으로 신경생물학적 메커니즘을 규명하고 있습니다. 특히 기억 재활성화 후 시냅스 단백질이 유비퀴틴-프로테아좀 경로에 의해 분해되는 과정이 기억 재형성에 필수적임을 밝혀내었으며, 이는 기억의 유지와 소실 메커니즘에 대한 새로운 통찰을 제공합니다. 또한 유방 초음파 영상에서의 elastography 기술을 활용한 진단 정밀도 향상 연구를 통해 임상적 응용가능성도 확장하고 있습니다.

기억 재형성프로테아좀유비퀴틴초음파 엘라스토그래피기억 메모리

연구 현황

논문 수
447
총 인용 수
8,238
최근 5년 논문
108
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
108총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
793총합
20222023202420252026

주요 논문

15
1
논문|인용수 128·2020
A hybrid image enhancement based brain MRI images classification technique
Zahid Ullah, Muhammad Umar Farooq, Su-Hyun Lee, Donghyeok An
SJR Q3FWCI 7.4Medical Hypotheses
NeurologyNeuroscience
2
논문|인용수 115·2012
Differentiation of benign from malignant solid breast masses: comparison of two-dimensional and three-dimensional shear-wave elastography
Su Hyun Lee, Jung Min Chang, Won Hwa Kim, Min Sun Bae, Nariya Cho, Ann Yi, Hye Ryoung Koo, Seung Ja Kim, Jin You Kim, Woo Kyung Moon
SJR Q1FWCI 8.2European Radiology
Radiology, Nuclear Medicine and ImagingMedicine
3
논문|인용수 113·2014
Added Value of Shear-Wave Elastography for Evaluation of Breast Masses Detected with Screening US Imaging
Su Hyun Lee, Jung Min Chang, Won Hwa Kim, Min Sun Bae, Mirinae Seo, Hye Ryoung Koo, A Jung Chu, Hye Mi Gweon, Nariya Cho, Woo Kyung Moon
SJR Q1FWCI 7.0Radiology

The addition of SWE to B-mode US improved diagnostic performance with increased specificity for screening US-detected breast masses. BI-RADS category 4a masses detected at US screening that showed a dark blue color or a maximum elasticity value of 30 kPa or less on SWE images can be safely followed up instead of performing biopsy.

Radiology, Nuclear Medicine and ImagingMedicine
4
리뷰|인용수 103·2013
Practice guideline for the performance of breast ultrasound elastography
Su Hyun Lee, Jung Min Chang, Nariya Cho, Hye Ryoung Koo, Ann Yi, Seung Ja Kim, Ji Hyun Youk, Eun Ju Son, Seon Hyeong Choi, Shin Ho Kook, Jin Chung, Eun Suk
SJR Q1FWCI 5.0ULTRASONOGRAPHYOA

Ultrasound (US) elastography is a valuable imaging technique for tissue characterization. Two main types of elastography, strain and shear-wave, are commonly used to image breast tissue. The use of elastography is expected to increase, particularly with the increased use of US for breast screening. Recently, the US elastographic features of breast masses have been incorporated into the 2nd edition of the Breast Imaging Reporting and Data System (BI-RADS) US lexicon as associated findings. This r

Radiology, Nuclear Medicine and ImagingMedicine
5
논문|인용수 87·2009
Development of third molars in Korean juveniles and adolescents
Soo‐Hyun Lee, Jeong-Yun Lee, Heekyung Park, Young-Ku Kim
SJR Q1FWCI 42.7Forensic Science International
ArcheologyArts and Humanities
6
논문|인용수 85·2017
Gait performance and foot pressure distribution during wearable robot-assisted gait in elderly adults
Suhyun Lee, Hwang-Jae Lee, Won Hyuk Chang, Byung‐Ok Choi, Jusuk Lee, Jeonghun Kim, Gyu-Ha Ryu, Yun‐Hee Kim
SJR Q1FWCI 2.5Journal of NeuroEngineering and RehabilitationOA

NCT02843828 .

Biomedical EngineeringEngineering
7
논문|인용수 75·2015
Effects of dexmedetomidine on oxygenation and lung mechanics in patients with moderate chronic obstructive pulmonary disease undergoing lung cancer surgery
Su Hyun Lee, Namo Kim, Chang Yeong Lee, Min Gi Ban, Young Jun Oh
SJR Q1FWCI 3.1European Journal of AnaesthesiologyOA

ClinicalTrial.gov identifier: NCT 02185430.

Pulmonary and Respiratory MedicineMedicine
8
논문|인용수 67·2016
Effect of Virtual Reality‐based Bilateral Upper Extremity Training on Upper Extremity Function after Stroke: A Randomized Controlled Clinical Trial
Su-Hyun Lee, Yumi Kim, Byoung‐Hee Lee
SJR Q1FWCI 3.4Occupational Therapy International

In the present study, we aimed to investigate the effect of virtual reality-based bilateral upper extremity training (VRBT) on paretic upper limb function and muscle strength in patients with stroke. Eighteen stroke survivors were assigned to either the VRBT group (n = 10) or the bilateral upper limb training group (BT, n = 8). Patients in the VRBT group performed bilateral upper extremity exercises in a virtual reality environment, whereas those in the BT group performed conventional bilateral

RehabilitationMedicine
9
논문|인용수 65·2017
Evaluation of Screening US–detected Breast Masses by Combined Use of Elastography and Color Doppler US with B-Mode US in Women with Dense Breasts: A Multicenter Prospective Study
Su Hyun Lee, Jin Chung, Hye Young Choi, Seon Hyeong Choi, Eun Bi Ryu, Kyung Hee Ko, Hye Ryoung Koo, Jeong Seon Park, Ann Yi, Ji Hyun Youk, Eun Ju Son, A Jung Chu
SJR Q1FWCI 3.9RadiologyOA

Purpose To investigate the value of the combined use of elastography and color Doppler ultrasonography (US) with B-mode US for evaluation of screening US-detected breast masses in women with dense breasts. Materials and Methods This prospective, multicenter study included asymptomatic women with dense breasts who were referred for screening US between November 2013 and December 2014. Eligible women had a newly detected breast mass at conventional B-mode US screening, for which elastography and c

Pathology and Forensic MedicineMedicine
10
리뷰|인용수 62·2020
Diffusion-Weighted Magnetic Resonance Imaging of the Breast: Standardization of Image Acquisition and Interpretation
Su Hyun Lee, Hee Jung Shin, Woo Kyung Moon
SJR Q1FWCI 3.2Korean Journal of RadiologyOA

Diffusion-weighted (DW) magnetic resonance imaging (MRI) is a rapid, unenhanced imaging technique that measures the motion of water molecules within tissues and provides information regarding the cell density and tissue microstructure. DW MRI has demonstrated the potential to improve the specificity of breast MRI, facilitate the evaluation of tumor response to neoadjuvant chemotherapy and can be employed in unenhanced MRI screening. However, standardization of the acquisition and interpretation

Radiology, Nuclear Medicine and ImagingMedicine
11
논문|인용수 61·2018
Functional Partitioning of Genomic Variance and Genome-Wide Association Study for Carcass Traits in Korean Hanwoo Cattle Using Imputed Sequence Level SNP Data
Mohammad Shamsul Alam Bhuiyan, Dajeong Lim, Mi Na Park, Soo-Hyun Lee, Soohyun Lee, Yeongkuk Kim, Cedric Gondro, Byoungho Park, Seunghwan Lee, Seunghwan Lee
SJR Q2FWCI 3.8Frontiers in GeneticsOA

Quantitative traits are usually controlled by numerous genomic variants with small individual effects, and variances associated with those traits are explained in a continuous manner. However, the relative contributions of genomic regions to observed genetic variations have not been well explored using sequence level single nucleotide polymorphism (SNP) information. Here, imputed sequence level SNP data (11,278,153 SNPs) of 2109 Hanwoo steers (Korean native cattle) were partitioned according to

GeneticsBiochemistry, Genetics and Molecular Biology
12
논문|인용수 57·2016
Intraoperative Dexmedetomidine Improves the Quality of Recovery and Postoperative Pulmonary Function in Patients Undergoing Video-assisted Thoracoscopic Surgery
Su Hyun Lee, Chang Yeong Lee, Jin Gu Lee, Namo Kim, Hye‐Mi Lee, Young Jun Oh
SJR Q3FWCI 5.4MedicineOA

Video-assisted thoracoscopic surgery (VATS) has been known to be a stressful event for patients, and dexmedetomidine is known to attenuate surgery-induced sympathetic responses and potentiate analgesia in perioperative periods. The present was designed to evaluate the effects of intraoperative dexmedetomidine administration on the quality of recovery (QoR) and pulmonary function after VATS. Patients with lung cancer undergoing VATS were randomized to Dex group (loading of 1.0 μg/kg for 20 minute

Anesthesiology and Pain MedicineMedicine
13
논문|인용수 56·2016
Tumor growth rate of invasive breast cancers during wait times for surgery assessed by ultrasonography
Su Hyun Lee, Young Seon Kim, Wonshik Han, Han Suk Ryu, Jung Min Chang, Nariya Cho, Woo Kyung Moon
SJR Q3FWCI 0.8MedicineOA

Several studies suggest that delay in the surgical treatment of breast cancer is significantly associated with lower survival. This study evaluated the tumor growth rate (TGR) of invasive breast cancers during wait times for surgery quantitatively using ultrasonography (US) and identified clinicopathologic factors associated with TGR.This retrospective study was approved by our institutional review board and the requirement for written informed consent was waived. Between August 2013 and Septemb

Cancer ResearchBiochemistry, Genetics and Molecular Biology
14
논문|인용수 50·2013
Two-View versus Single-View Shear-Wave Elastography: Comparison of Observer Performance in Differentiating Benign from Malignant Breast Masses
Su Hyun Lee, Nariya Cho, Jung Min Chang, Hye Ryoung Koo, Jin You Kim, Won Hwa Kim, Min Sun Bae, Ann Yi, Woo Kyung Moon
SJR Q1FWCI 4.0Radiology

The performance of radiologists in differentiating benign from malignant breast masses was improved when B-mode US was combined with two-view SWE compared with that when B-mode US was combined with single-view SWE.

Radiology, Nuclear Medicine and ImagingMedicine
15
논문|인용수 49·2018
THICKNESSES OF CENTRAL MACULAR, RETINAL NERVE FIBER, AND GANGLION CELL INNER PLEXIFORM LAYERS IN PATIENTS WITH HYPERTENSION
Soo-Hyun Lee, Woo Hyuk Lee, Hyung Bin Lim, Young Joon Jo, Jung‐Yeul Kim
SJR Q1FWCI 4.1Retina

The central macula, RNFL, and GCIPL in Group B were significantly thinner than those of healthy eyes, and these retinal changes were more prominent in Group C. Thus, the effects of retinal changes associated with hypertension should be considered when analyzing the thicknesses of the central macular, RNFL, and GCIPL layers in patients with ocular disorders, including retinal, glaucoma, and neuro-ophthalmological diseases.

Radiology, Nuclear Medicine and ImagingMedicine

대표 연구 분야

Radiology, Nuclear Medicine and ImagingAerospace EngineeringPulmonary and Respiratory MedicineCancer ResearchGeneticsSociology and Political Science

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