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Muscle hypertrophy is the product of increased drive through protein synthetic pathways and the incorporation of newly divided satellite cells. Gains in muscle mass and strength can be achieved through exercise regimens that include resistance training. Increased insulin-like growth factor-I (IGF-I) can also promote hypertrophy through increased protein synthesis and satellite cell proliferation. However, it is not known whether the combined effect of IGF-I and resistance training results in an

We develop a new principal components analysis (PCA) type dimension reduction method for binary data. Different from the standard PCA which is defined on the observed data, the proposed PCA is defined on the logit transform of the success probabilities of the binary observations. Sparsity is introduced to the principal component (PC) loading vectors for enhanced interpretability and more stable extraction of the principal components. Our sparse PCA is formulated as solving an optimization proble

The explosion in the amount of information that is being processed is prompting the need for new computing systems beyond existing electronic computers. Photonic computing is emerging as an attractive alternative due to performing calculations at the speed of light, the change for massive parallelism, and also extremely low energy consumption. We review the physical implementation of basic optical calculations, such as differentiation and integration, using metamaterials, and introduce the reali

RESISTANCE TRAINING INDUCES MUSCLE -SPECIFIC CHANGES IN MUSCLE MASS AND FUNCTION IN RAT. Sukho Lee, Roger P. Farrar. JEPonline. 2003;6(2):80-87. Resistance exercise is frequently used to induce hypertrophy in animal model. T his study examined the effects of 8 weeks of resistance training followed by 4 to 8 weeks of detraining on muscle mass and function. The resistance training consisted of climbing (5 reps/3 sets) a ladder carrying a load suspended from the tail. The weights were increased gra

Genome‐Wide association studies (GWAS) routinely apply principal component analysis (PCA) to infer population structure within a sample to correct for confounding due to ancestry. GWAS implementation of PCA uses tens of thousands of single‐nucleotide polymorphisms (SNPs) to infer structure, despite the fact that only a small fraction of such SNPs provides useful information on ancestry. The identification of this reduced set of Ancestry‐Informative markers (AIMs) from a GWAS has practical value;

We propose a new data perturbation method for numerical database security problems based on skew-t distributions. Unlike the normal distribution, the more general class of skew-t distributions is a flexible parametric multivariate family that can model skewness and heavy tails in the data. Because databases having a normal distribution are seldom encountered in practice, the newly proposed approach, coined the skew-t data perturbation (STDP) method, is of great interest for database managers. We

Controversial results reported in past research pertaining to the effectiveness of sport-based physical activity interventions on weight loss. The purpose of this study was to assess the impact of sport-based physical activity intervention on body weight in children and adolescents using a meta-analysis. Academic Search Complete, Education Source, ERIC, Medline, ProQuest, PsycINFO and SportDiscus databases were searched from January 2000 to April 2015. Eighteen studies met following inclusion cr

AFRS is believed to be an allergic response to colonizing fungi in atopic individuals. In EFRS, local allergies to fungi may play a role in the pathogenesis of the disease. EMRS is thought to be unconnected with fungal allergies.

In the present study, we investigated the effects of previous strength training and retraining following long-term cessation of exercise on muscle mass and contractile properties. Female Sprague-Dawley rats (n=24) aged eight weeks were randomly assigned one of the four groups: control (CON), detraining (DT), training (TR), and retraining (RT). The training regimen consisted of climbing ladder 5×3 sets, once every third day for eight weeks with weight attached to the tail. The weight carried duri

Skeletal muscle atrophy, induced by 14 days of cast-immobilization, was significantly attenuated by acupuncture, electro-acupuncture, or electrical stimulation.