김선욱 교수
Sun Wook Kim
서울대학교 · 의학
연구실 소개
김선욱 교수의 연구실은 노화 및 내과적 질환의 복합적 평가를 중심으로, 노인 환자의 수술 예후 예측, 갑상선 질환의 조기 진단 및 분자적 특성 분석, 그리고 신체 구성과 대사 상태의 정밀 평가를 위한 생물학적 지표 개발에 주력하고 있습니다. 특히 종양 핵의학 영상에서 발견되는 갑상선 임시 발견소견의 악성도 평가와 BRAF 유전자 변이 분석을 통해 갑상선암의 진단 정밀도를 높이는 데 기여하고 있으며, 신장 기능과 근육량 추정의 정확도 향상에도 기여하고 있습니다. 연구는 임상적 실용성과 장기적 건강 결과 예측에 초점을 맞추고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15The multidimensional frailty score based on comprehensive geriatric assessment is more useful than conventional methods for predicting outcomes in geriatric patients undergoing surgery.
The new equation based on serum creatinine and cystatin C levels can be used to estimate total-body muscle mass.
Flow of fluids through the gut, such as milk from a neonatal diet, generates a shear stress on the unilaminar epithelium lining the lumen. We report that exposure to physiological levels of fluid shear stress leads to the formation of large vacuoles, containing extracellular contents within polarizing intestinal epithelial cell monolayers. These observations lead to two questions: how can cells lacking primary cilia transduce shear stress, and what molecular pathways support the formation of vac
The authors had performed a complete excision of paraffinoma in patients with penile paraffinoma with concurrent skin necrosis and obtained good outcomes of preventing the shortening of penile length by performing a bipedicled scrotal flap with Y-V incision using the scrotal skin.
UGS and MAC are viable methods of clinically screening for frailty.
Potential conflict of interest: Nothing to report. To the Editor: We read the article by Hong et al.1 with great interest because the concept of sarcopenia has been emerging as a major issue in many fields. In the study by Hong et al., sarcopenia was defined by a state of decreased percent muscle mass as skeletal muscle mass index (SMI) of 1 SD below the sex‐specific mean value. They reported that participants in the sarcopenia group had greater body mass index (BMI) as well as high body fat mas
, .
Purpose: We evaluated the early results and the learning curve of laparoscopic radical prostatectomy in the first 150 patients. Materials and Methods: Between July 2001 and March 2007, 150 consecutive patients with clinically organ-confined prostate cancer underwent laparoscopic radical prostatectomy. For evaluation of the learning curve, morbidity, oncologic, and functional results of the first 50 (group 1) and last 50 (group 3) procedures were compared. Results: The mean operating time and hos
During the past decades, the world's population has continued on its remarkable transition from a state of high birth and death rates to low birth and death rates. As a result, the number of elderly people, and particularly of the very elderly people, is increasing throughout the world. This demographic change has profound implication for medical and health care systems. As more people live to advanced old age, it is important to understand the chronic diseases and health problems which affect t
OAB may occur in approximately 18% of SUI patients who undergo MUS surgery, and voiding dysfunctions with deteriorated voiding symptom and storage symptom may also occur. The deteriorated OAB was shown in 45% of SUI patients with OAB after the surgery.
Background: Clinical trials are widely used to approve the efficacy and discover adverse reactions of new drugs. However, there has been much concern about the unjustified exclusion of the older adults in clinical trials. The purpose of this study was to assess ageism in clinical trials and to find solution to any discovered discrimination. Methods: An online questionnaire was completed by 1,650 experts including doctors, pharmaceutical staff, and contract research organization members. An offli
Objective: Atrial fibrillation is the common arrhythmia in the elderly, and the average age of atrial fibrillation patients is rising. Elderly patients with atrial fibrillation have high incidence of thromboembolic complication and increasing age is associated with stroke severity. Assessing CHADS-VASc score is pivotal to evaluate substantial morbidity and mortality, especially regarding the increased risk of stroke. In addition, considering bleeding risk with HAS-BLED score is important to bala
Addressing barriers to deprescribing in South Korea requires a multifaceted approach, including public awareness campaigns, healthcare provider education, prescription sharing systems, and a geriatric primary care system. Long-term policies incentivizing appropriate medication use and supporting deprescribing interventions are necessary for sustainable medication management in older adults.
The study suggests that the HOME system provides higher quality of care and safer environment compared to conventional oncologist-led team-based care, and the efficiency of the medical delivery system could be increased by reducing the hospitalization period without increase in 30-day unplanned re-admission.
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