권택균 교수
Tack Kyun Kwon
서울대학교 · 의학
연구실 소개
권택균 교수의 연구실은 주로 음성 장애와 관련된 보조 수술 치료, 특히 비특이성 음성 이상과 노령성 뇌병변(예: 노령성 림프구성 음성 장애)의 치료에 초점을 맞추고 있습니다. 특히 칼슘 하이드로우로이드(CaHA)를 이용한 인젝션 레이노플라스티 등 보존적 음성 수술 기법의 유효성과 안정성을 평가하며, 유전자 다형성과 질병의 연관성 등 분자 수준의 기전 규명에도 기여하고 있습니다. 또한 외상성 또는 신경성 음성 장애 환자의 회복 가능성과 치료 시기의 관계를 분석해, 개인 맞춤형 치료 전략 수립에 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15In recent years, the application of injection laryngoplasty to unilateral vocal fold paralysis (UVP) has regained popularity. The technique of injection laryngoplasty has several appealing qualities including relative technical ease, low cost, and wide availability in many clinical settings. A growing number of injectable substances have been developed and tested in the clinical setting of glottic insufficiency. When used to manage unilateral vocal fold paralysis, however, injection laryngoplast
The authors conclude that CaHA injection laryngoplasty offers an effective and safe means of treating presbylaryngis.
4 Laryngoscope, 129:2361-2365, 2019.
A linear association between injury level and maximum recovery time was observed. The findings suggest that the decision to proceed with permanent phonosurgical treatment should be based on the level of injury associated with UVFP.
IV (Case series).
We showed that Foxp3 polymorphism of rs5902434 and rs2232365 could be an important protective factor in the susceptibility of severe RRP in female Koreans. Further studies on larger number of patients and other ethnic groups are needed to clarify the association.
A half of atypia of undetermined significance (category III) cases were malignant. Once diagnosed, the prognosis of malignant tumor in category III was similar with that in category V/VI.
Endoscopic arytenoid adduction using a cricoid implant is feasible and could be a noninvasive surgical option for the treatment of unilateral vocal fold paralysis.
In all, 24 patients were treated with the endoscopic technique. Among the six open laryngotracheal reconstructions, cricoid splitting and rib cartilage graft were performed in four patients and laryngotracheal resection and end-to-end anastomosis were performed in two patients. Stenosis to normal ratio tended to increase after endoscopic intervention, but it did not show statistical significance (p = 0.082). Open surgery did not cause significant narrowing (p = 0.443).
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