이태민 교수
Tae Min Rhee
서울대학교 · 의학
연구실 소개
이태민 교수의 연구실은 심혈관 질환의 예방과 조기 진단을 중심으로 한 다학제적 연구를 수행하고 있습니다. 특히 급성 청력저하, 심부전, 혈관성 질환 등에서의 생존율 향상 및 위험 요소 분석을 위해 임상적 기반의 머신러닝 모델 개발과 환자 특성 분류에 중점을 두고 있습니다. 또한 환경적 요인(미세먼지)과 유전적 소인의 상호작용이 심혈관 질환에 미치는 영향을 규명하며 개인 맞춤형 예방 전략의 가능성을 탐색하고 있습니다. 특히 고위험군의 조기 식별과 최적 치료 전략 수립을 위한 임상 연구와 데이터 기반 모델링이 융합된 연구가 특징입니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15The addition of HBOT to standard MT is a reasonable treatment option for SSNHL, particularly for those patients with severe to profound hearing loss at baseline and those who undergo HBOT as a salvage treatment with a prolonged duration. Optimal criteria for patient selection and a standardized regimen for HBOT should be applied in routine practice, with future trials to investigate maximal treatment benefit.
Psoriasis increases the risk of atrial fibrillation (AF) and thromboembolic events (TE). There is limited information on the effect of psoriasis severity on AF and TE. In this study, psoriasis patients were enrolled from the Korean National Insurance Service-National Sample Cohort (2004-2008). Diagnosis and disease severity were determined from claims data. Newly diagnosed non-valvular AF and TE were identified during a 9.6-year follow-up. The effect of psoriasis severity on AF and TE was evalua
[PROSPERO], identifier [CRD42021241718].
LSD is uncommon with contemporary drug-eluting stents, regardless of the type of stent platform. LSD is mainly associated with procedural factors, especially with additional downstream procedures which require the passage of devices through the stent. Careful manipulation of poststent imaging or procedural devices is required to prevent LSD. More data are needed to clarify the impact of LSD on clinical events.
The proposed ML models incorporating various phenotypes from patients with HCM accurately discriminated adverse cardiovascular events and provided variables with high importance for each outcome.
A combination of greater PM<sub>2.5</sub> exposure and higher genetic predisposition to particular CVDs was modestly associated with elevated risks of cardiovascular death and CVDs. Not only alleviating PM<sub>2.5</sub> exposure in the general population but also implementing individualized preventive approach for those at high genetic risk might be beneficial.
ClinicalTrials.gov Identifier: NCT02044250.
In middle-aged and elderly Koreans without CVD, baPWV was identified as having a moderately positive correlation with four different risk scores. The correlation was stronger in women than in men, implying the better performance of baPWV in women for predicting cardiovascular risk of healthy population.
Severe migraine with aura significantly increased the risk of incident AF in women, but not in men. Surveillance for incident AF and prompt lifestyle modification may be beneficial, particularly for young women suffering from severe migraine with aura.
Having a higher BMI than genetically predicted is associated with an increased risk of T2D. These findings underscore the potential to reassess T2D risk based on individual levels of obesity using genetic thresholds for BMI.
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