Takato Mitsudome

With increasing demand for efficient organic transformations based on the concept of Green Sustainable Chemistry, the development of highly selective reaction systems using heterogeneous catalysts is greatly desired. In selective hydrogenation using heterogeneous catalysts, gold nanoparticle catalysts have recently attracted enormous attention due to their unique catalysis compared with that of conventional hydrogenation catalysts based on Pt, Pd, and Ru nanoparticles. This review describes rece

Although the development of metal nanoparticle catalysts for organic synthesis has been widely studied, the catalytic potential of “metal phosphide nanoparticles” has little been studied. Herein, we describe that nickel phosphide nanoparticles (Ni2P NPs) act as a highly efficient heterogeneous catalyst for the selective transformation of biofuranic aldehydes into diketones, which is a useful biorefining technology. The biofuranic aldehydes are hydrogenated in water without any additives, giving

The study of metal phosphide catalysts for organic synthesis is rare. We present, for the first time, a well-defined nano-cobalt phosphide (nano-Co₂P) that can serve as a new class of catalysts for the hydrogenation of nitriles to primary amines. While earth-abundant metal catalysts for nitrile hydrogenation generally suffer from air-instability (pyrophoricity), low activity and the need for harsh reaction conditions, nano-Co₂P shows both air-stability and remarkably high a

Hydrogenation of amides to amines is an important reaction, but the need for high temperatures and H₂ pressures is a problem. Catalysts that are effective under mild reaction conditions, that is, lower than 30 bar H₂ and 70 °C, have not yet been reported. Here, the mild hydrogenation of amides was achieved for the first time by using a Pt-V bimetallic catalyst. Amide hydrogenation, at either 1 bar H₂ at 70 °C or 5 bar H₂ at room temperature was achieve

While metal phosphides have begun to attract attention as electrocatalysts, they remain underutilized in the field of liquid-phase molecular transformations. Herein, we describe a supported cobalt phosphide nanoalloy (nano-Co2P) that functions as a highly efficient, reusable heterogeneous catalyst for the selective hydrogenation of furfural derivatives. The carbonyl moieties of several furfural derivatives were selectively hydrogenated to produce the desired products in high yields. In contrast

Caught making a change: Stable sub-nanoordered Pd clusters within the interlayer spaces of montmorillonite efficiently catalyze heterogeneous allylic substitution reactions in which the coordinatively unsaturated Pd atoms enable facile formation of π-allylpalladium intermediates (see scheme). The catalyst is reusable without any loss of activity or selectivity. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z604644_s.pdf or fro

Abstract A TiO 2 ‐supported, gold nanoparticle catalyst was found to allow the N‐formylation of various amines, including normally unreactive anilines, by using CO 2 as the carbonyl source under a H 2 atmosphere. A series of reducible functional groups, such as olefins, halogens, carbonyls, carbamates, and cyano moieties, were completely retained during the formylation, which proved the highly selective nature of the formylation reaction. The catalyst was also found to be reusable without any lo

The first demonstration of the hydrogenation of sulfoxides under atmospheric H2 pressure is reported. The highly efficient reaction is facilitated by a heterogeneous Ru nanoparticle catalyst. The mild reaction conditions enable the selective hydrogenation of a wide range of functionalized sulfoxides to the corresponding sulfides. The high redox ability of RuO(x) nanoparticles plays a key role in the hydrogenation.

An efficient and sustainable <sc>d</sc>-sorbitol production <italic>via</italic><sc>d</sc>-glucose hydrogenation was achieved over a hydrotalcite-supported nickel phosphide nanoparticle catalyst with stability, high activity and reusability.

Innere Werte: Ein einfaches Katalysatorsystem bestehend aus PdCl2 und N,N-Dimethylacetamid (DMA) als Lösungsmittel vermittelt die Wacker-Oxidation interner Alkene. Dabei werden keine Kupferverbindungen benötigt, und es lassen sich vielfältige Substrate mit internen Doppelbindungen umsetzen.

Exploring novel catalysis by less common, metal-non-metal nanoalloys is of great interest in organic synthesis. We herein report a titanium-dioxide-supported nickel phosphide nanoalloy (nano-Ni2P/TiO2) that exhibits high catalytic activity for the deoxygenation of sulfoxides. nano-Ni2P/TiO2 deoxygenated various sulfoxides to sulfides under 1 bar of H2, representing the first non-noble metal catalyst for sulfoxide deoxygenation under ambient H2 pressure. Spectroscopic analyses revealed that this

Metal phosphide catalysts have attracted attention for organic synthesis owing to their stability and high activity. Nevertheless, metal–support interactions and support-boosted metal phosphide catalysis remain unexplored. Herein, we report the development of a hydrotalcite (HT: Mg6Al2CO3(OH)16·4(H2O))-supported nickel phosphide nanoalloy (nano-Ni2P/HT) that exhibits high activity for the hydrogenation of maltose, which is an important reaction for producing maltitol as a sweetener and food addi

Gefangen aktiv: Stabile Pd-Cluster zwischen den Schichten von Montmorillonit katalysieren allylische Substitutionen effizient, wobei die koordinativ ungesättigten Pd-Atome die Bildung von π-Allylpalladium-Zwischenstufen ermöglichen (siehe Schema). Der Heterogenkatalysator lässt sich ohne Verlust an Aktivität oder Selektivität wiederverwenden.

Abstract Hydrogenation of amides to amines is an important reaction, but the need for high temperatures and H 2 pressures is a problem. Catalysts that are effective under mild reaction conditions, that is, lower than 30 bar H 2 and 70 °C, have not yet been reported. Here, the mild hydrogenation of amides was achieved for the first time by using a Pt‐V bimetallic catalyst. Amide hydrogenation, at either 1 bar H 2 at 70 °C or 5 bar H 2 at room temperature was achieved using the bimetallic catalyst