이원재 교수

Diphenhydramine chloride significantly reduced mortality in rats with acute, severe dichlorvos exposure.

Objective: To evaluate the effects of diphenhydramine chloride (DPH) on mortality in a rat model of acute, severe organophosphate poisoning (OP). Methods: Wistar rats (n = 40) were randomized to pretreatment with either normal saline (controls), 5 mg/kg atropine, 3 mg/kg DPH, 15 mg/kg DPH, or 30 mg/kg DPH given as a single intramuscular injection 5 minutes prior to a subcutaneous injection of 25 mg/kg dichlorvos (n = 8 per group). The primary endpoint was 10‐minute survival. Survival at 24 hours

Extracellular proteases play an important role in a wide range of host physiological events, such as food digestion, extracellular matrix degradation, coagulation and immunity. Among the large extracellular protease family, serine proteases that contain a "paper clip"-like domain and are therefore referred to as CLIP-domain serine protease (clip-SP), have been found to be involved in unique biological processes, such as immunity and development. Despite the increasing amount of biochemical infor

본 연구의 목적은 첫째, 한국 실업 남자 핸드볼 팀 감독의 변혁적 리더십이 선수들의 심리적 임파워먼트와 조직시민행동에 미치는 영향을 알아보고, 둘째, 변혁적 리더십과 조직시민행동의 관계에서 선수들의 임파워먼트가 매개효과를 가지는지를 검증하고자 하는 것이다. 2009년 한국 실업 핸드볼 연맹 남자부에 등록되어 있는 선수 전체를 대상으로 설문조사를 실시하였으며, 회귀분석 이용한 매개분석을 통해 변혁적 리더십과 조직시민행동 간의 관계에 있어서의 임파워먼트의 매개효과를 검증하고자 하였다. 연구 결과, 핸드볼 팀 감독의 변혁적 리더십이 선수들의 임파워먼트와 조직시민행동에 유의미하게 긍정적인 영향을 미쳤으며, 이들 세 변인들 간에는 밀접한 상호관련성이 있는 것으로 나타났다. 이에 더하여 선수들의 임파워먼트는 감독의 변혁적 리더십과 조직시민행동 사이에서 두 변인들 간의 관계를 완전 매개하는 것으로 확인되었다. 이는 변혁적 리더십이 선수들의 조직시민행동에 영향을 미치는데 그것을 가능하게 하는 기제

The transient response of S- and S/sup +/-band thulium-doped fiber amplifiers with 1.4-μm/1.5-μm dual-wavelength pumping scheme was investigated both experimentally and theoretically. In contrast to conventional Erbium-doped fiber amplifiers, two characteristic time-constants related with <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> F <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sub> an

We analyze the gain excursion and tilt function of the thulium doped fiber amplifiers (TDFAs) for the 1.4- and 1.5-μm dual-wavelength pump approach. We also reveal that those two pump wavelengths act as independent control. factors for gain level and tilt function, because each pumps influence the populations of the first and second excited states ( <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> H <sub xmlns:mml="http://www.w3.org/1998/Math

In the last few years, researches on autonomous ships have attracted attention. One of the essential techniques required for autonomous ships is the awareness of surroundings, including detection and classification of objects. Although researches on computer vision regarding the classification of ship images are still making progress, it is challenging to encounter a lack of enough database that was adequately labeled for ship classification. In this study, data obtained from Singapore Maritime

스포츠의 세계화는 미디어의 발달을 통해 가속화되어 가고 있으며, 한국 사회도 예외가 아니다. 본 연구는 스포츠세계화의 흐름 속에서 한국사회가 직면하고 있는 현실을 진단함으로써 정책적 시사점을 도출하는 것을 목적으로 수행되었다. 연구의 결과로, 한국에서의 스포츠세계화는 국내 콘텐츠의 유출과 해외 콘텐츠의 유입이라는 두 가지 차원에서 불균형성이 심화되고 있는 것으로 확인되었으며, 이러한 맥락에서 스포츠콘텐츠의 1) 자원적 측면, 2) 생산적 측면, 3) 유통적 측면, 4) 소비적 측면에서의 불균형성을 해결하기 위한 정책적 시사점이 제시되었으며, 한국 스포츠의 글로벌 스포츠 콘텐츠로서의 생산과 유통의 확대를 위한 방안도 논의되었다.

Summary form only given. We investigated some of the key issues of the amplifier application in WDM systems such as gain tilt and gain excursion, along with their compensating techniques. We explained the gain excursion/tilt behavior of thulium-doped fiber amplifier (TDFA) under 1.4 /spl mu/m/1.5 /spl mu/m main/subsidiary pumping scheme. It was found that it is necessary to control both wavelengths to completely compensate the induced gain excursion from the channel add/drops. With coarse tuning

A study on the optimal size of toothbrush for Koreans

With the fast consumption of transmission bandwidth, the gain flattened erbium-doped fiber amplifies (EDFA) now became an essential element for realizing high capacity long-haul wavelength division multiplexing (WDM) transmission systems. Most recent development now includes long wavelength amplifiers, which can support more than 80 nm's of the wide, flat gain window when combined with the normal EDFA. There has not been serious investigation on the temperature effect on the multichannel gain of

Stress-induced cardiomyopathy is characterized by reversible systolic dysfunction of the ventricles, usually involving the apical segments. It occurs more commonly in women and is frequently precipitated by emotional or physical stressors. Ever since the first report of typical stress-induced cardiomyopathy-usually known as Takotsubo cardiomyopathy or transient left ventricular apical ballooning syndrome-was issued, variant forms of stress-induced cardiomyopathy have been reported. We describe a

Background and Objectives: The National Cholesterol Education Program-Adult Treatment Panel (NCEP-ATP) III guideline has been widely accepted for the primary prevention of coronary heart disease (CHD). The coronary artery calcium score (CACS) has recently been recognized as an excellent predictor of CHD events, and a primary prevention strategy based on the CACS [the Screening for Heart Attack Prevention and Education (SHAPE) guideline] has been proposed. The purpose of this study was to explore

Background and Objectives: The prevalence of arthritis, which is often treated with celecoxib, is high in patients with coronary artery disease. Furthermore, celecoxib has been reported to reduce restenosis after coronary stenting by inhibiting expression of the proto-oncogene Akt. A concern is that celecoxib increases thrombogenicity by inhibiting the synthesis of prostacyclin in endothelial cells. However, it is not known whether the administration of celecoxib will attenuate the antiplatelet