한유민 교수
Yoo Min Han
서울대학교 · 의학
연구실 소개
한유민 교수의 연구실은 소화기계 질환, 특히 간장질환과 염증성 장질환(IBD)의 병태생리학적 기전과 치료 전략을 중심으로 연구를 진행하고 있습니다. 특히 불안·우울과 위식도역류질환(GERD)의 연관성, 미네랄 결핍이 장염성 질환에 미치는 영향, NF-κB 경로의 역할 및 천연물질의 항염증 효과에 대한 기초 및 임상 연구를 병행하고 있습니다. 또한 혈관성 학질환의 진단 및 치료 기법, 특히 내 endoscopic 수술을 통한 합병증 관리에도 전문성을 기르고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15This cross-sectional study revealed that anxiety and depression levels were significantly higher in subjects with GERD (notably in the NERD) than in controls.
Many Korean patients with IBD have vitamin D, zinc, and selenium deficiencies, suggesting the necessity for monitoring levels of these micronutrients.
Crohn's disease patients with high NF-κB activation showed specific clinical manifestations of higher frequency of ileocolonic involvement and lower frequency of perianal involvement relative to those with low NF-κB activation. High NF-κB activity was associated with higher histologic scores. However, the NF-κB activity did not affect the outcome and disease course after surgery.
Patients with Crohn's disease and perianal lesions had a higher risk of reoperation. Considering these findings, physicians should consider aggressive and early top down therapy for patients with perianal Crohn's disease.
Astragalin exerted an anti-inflammatory effect through NF-κB pathway inhibition and attenuated murine colitis. Astragalin is thus a potential therapeutic agent for IBD.
Splenic artery pseudoaneurysms can be caused by pancreatitis, trauma, or operation. Traditionally, the condition has been managed through surgery; however, nowadays, transcatheter arterial embolization is performed safely and effectively. Nevertheless, several complications of pseudoaneurysm embolization have been reported, including coil migration. Herein, we report a case of migration of the coil into the jejunal lumen after transcatheter arterial embolization of a splenic artery pseudoaneurys
Background/Aims: Studies on the micronutrient status of Asian patients with inflammatory bowel disease (IBD) are scarce. We evaluated the prevalence of micronutrient deficiency and verified the risk factors for micronutrient deficiency in Korean patients with IBD. Methods: We measured the serum levels of 25-hydroxyvitamin D3 [25-(OH)D], zinc, and selenium to analyze the clinical risk factors for micronutrient levels below the reference values. In addition, we compared the 25-(OH)D levels of pati
While Hp seropositivity was not associated with CAP-defined NAFLD, serum HDL cholesterol level were negatively associated with Hp-seropositivity in both groups with and without NAFLD. Further clinical and experimental studies are necessary to determine the association between Hp infection and NAFLD.
Colon capsule endoscopy (CCE) is a noninvasive technique for diagnostic imaging of the colon. It does not require air inflation or sedation and allows minimally invasive and painless colonic evaluation. The role of CCE is rapidly evolving; for example, for colorectal screening (colorectal cancer [CRC]) in average-risk patients, in patients with an incomplete colonoscopy, in patients refusing a conventional colonoscopy, and in patients with contraindications for conventional colonoscopy. In this
The extent of EAG and SAG exhibited strong inverse relationships with the occurrence and severity of GERD. AG followed by <i>H. pylori</i> infection may be independently protect against GERD.
Parenteral iron therapy appears to be more efficient than oral iron therapy. Physicians should focus on the iron deficiency of IBD patients and consider parenteral iron supplements in appropriate patient groups.
A family history of GC and low baseline PGI/II were independently associated with an increased risk of progression of precursor lesions of GC.
a study from the United States, many patients skipped or postponed screenings during the initial months of the pandemic. 6lthough these reductions improved following the early pandemic, the new reductions during the Delta and Omicron waves demonstrated the continued impact of the COVID-19 pandemic on cancer care.Although some rebound occurred, it was lower than expected.Despite several epidemic waves of COV-ID-19 in Korea, colonoscopy and the management of CRC remained unaffected after the first
INTRODUCTION: Visceral obesity is a risk factor for reflux esophagitis (RE). We investigated the risk of RE according to visceral adipose tissue (VAT) measured by deep neural network architecture using computed tomography (CT) and evaluated the longitudinal association between abdominal adipose tissue changes and the disease course of RE. METHODS: Individuals receiving health checkups who underwent esophagogastroduodenoscopy (EGD) and abdominal CT at Seoul National University Healthcare System G
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