김윤정 교수

Peroxiredoxin 1 (Prx1) has been found to be elevated in several human cancers. The cell survival-enhancing function of Prx1 is traditionally attributed to its reactive oxygen species-removing capacity, although the growth-promoting role of Prx1 independent of this antioxidant activity is increasingly gaining attention. Although much progress has been made in understanding the behavior of Prx1, little information is available on the mechanism responsible for the abnormal elevation of Prx1 level i

Spatial visitation patterns and its features on nature-based tourism are difficult to assess using only a field-based survey, which is costly and labor intensive. However, understanding of a protected area's visitation status is critical, as it can strongly influence the sustainability of natural resources. Hence, it is important to identify ‘where people visit’ and ‘why people visit,’ to evaluate the features attractive to tourists. In this regard, we proposed and applied social big data to inv

Radiotherapy is one of the major treatment modalities for lung cancer. Cell killing by ionizing radiation is mediated primarily through the reactive oxygen species (ROS) and ROS-driven oxidative stress. Prx1, a peroxiredoxin family member, was shown to be frequently elevated in lung cancer cells and tissues. Although the antioxidant function of Prx1 is expected to affect the radiotherapy response of lung cancer, the physiologic significance of its peroxidase activity in irradiated cells is uncle

The gingiva and buccal bone of the anterior maxillary teeth were found to be relatively thin (<1 mm) overall. A tendency was found for gingival thickness to increase and bone thickness to decrease toward the root apex. Differences were found between teeth at some positions, although the correlation between buccal bone thickness and soft tissue thickness was generally not significant.

Nature-based tourism contributes to the conservation of biodiversity by offering financial stability and enhancing visitors’ interest in nature, and thus has become an increasingly important issue in managing protected areas. However, unsustainable tourism can adversely affect biodiversity due to increased human traffic, and can devastate a wilderness area. Although the demand for nature-based tourism is on the rise, monitoring tourist’s spatial visitation pattern and its characteristics in prot

Many preclinical reports and retrospective population studies have shown an anticancer effect of metformin in patients with several types of cancer and comorbid type 2 diabetes mellitus (T2DM). In this work, the anticancer effect of metformin was assessed in hepatocellular carcinoma (HCC) patients with T2DM who underwent curative resection.A population-based retrospective cohort design was used. Data were obtained from the National Health Insurance Service and Korea Center Cancer Registry in the

Purpose: Identification of tolerable alternative analgesics is crucial for management in nonsteroidal anti-inflammatory drug (NSAID)-sensitive patients. We investigated cross-reactivity of acetaminophen and celecoxib according to the type of aspirin/NSAID hypersensitivity and aimed to determinethe risk factors for cross-intolerance. Methods: We retrospectively reviewed the medical records of patients intolerant to aspirin and NSAIDswho had undergone an acetaminophen and/or celecoxib oral provoca

본 연구는 식사의 질이 떨어지는 12~24개월 영유아의기질과 식행동, 어머니의 식행동과 식사지도방법의 특성을분석하였으며 그 결과를 요약하면 다음과 같다. 1) 조사 대상자의 남녀 분포는 PE 집단의 경우 남자42.3%, 여자 57.7%, NC 집단은 남자 58.5%, 여자 41.5% 로 유의적인 차이는 없었다. 어머니의 교육수준, 가족의 월수입과 아버지의 직업의 경우 두 집단간 유의적인 차이는없었으며, 아버지의 직업은 두 집단 모두‘사무직 또는 전문직’이 높았고(PE, 66.7%; NC, 69.8%), 어머니는‘직업이 없다’가 높은 경향을 보였다(PE, 77.8%; NC, 77.4%). 나이에 따른 신장과 체중의 Z-score는 두 그룹간 차이는없었으며, 모두 정상범위였다(-1 ≤ Z-score ≤ 1). 2) 영유아의 식사 도구 시작 시기는 컵의 경우는 PE 집단은 9.9개월, NC 집단은 9.5개월, 빨대의 경우는 PE 집단은 10.2개월, NC 집단은 10.1개월, 숟가락의 경

Base excision repair (BER) is an evolutionarily conserved pathway, which could be considered the “workhorse” repair mechanism of the cell. In particular, BER corrects most forms of spontaneous hydrolytic decay products in DNA, as well as everyday oxidative and alkylative modifications to bases or the sugar phosphate backbone. The repair response involves five key enzymatic steps that aim to remove the initial DNA lesion and restore the genetic material back to its original state: (i) excision of

This study aimed to investigate the effect of interdental brushes and dental floss on the prevention of periodontitis in participants with ≥ 20 or < 20 remaining teeth by using the Korea National Health and Nutrition Examination Survey 2016-2018. Data from 11,614 participants were analysed using multivariate logistic regression after adjusting for sociodemographic factors (age and sex), socioeconomic factors (level of education and individual income), oral health-related variables (daily toothbr

The primary purpose of this study is to explore the experiences of South Korean women “doing serious leisure” in what is widely known as a stigmatized activity, pole dance. It seeks to understand the experiences of South Korean women participating in pole dance and to investigate the strategies that are used to cope with the stigma that is experienced during participation. A qualitative research method was applied with an “insider” approach to collecting data. Data were collected through partici