임연희 교수
Youn Hee Lim
서울대학교 · 환경과학
연구실 소개
임연희 교수의 연구실은 환경오염 물질이 인체, 특히 어린이와 노인을 포함한 취약군의 정신건강 및 발달에 미치는 영향을 중심으로 연구를 진행하고 있습니다. 대기오염물질(PM10, NO2, O3, 초미세먼지 등)과 화학물질(BPA, PFAS 등)의 노출이 우울증, ADHD 증상, 체질량지수 변화 및 유전자 메틸화 변화에 미치는 영향을 생물학적 메커니즘과 함께 규명하고자 합니다. 특히 조기 생애 시기의 노출이 장기적인 건강 결과에 미치는 영향을 다각도로 분석하는 데 초점을 맞추고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Our study suggests that increases in PM10, NO2, and O3 may increase depressive symptoms among the elderly. Of the symptoms evaluated, ambient air pollution was most strongly associated with emotional symptoms.
All bisphenols, in particular those at or above the LOD or median levels, were associated with ADHD symptoms at age 6. Further prospective studies are warranted to determine causal inference.
Prenatal exposure to BPA may influence differential methylation of IGF2R at age 2. This result indicates that a possible sensitive period of DNA methylation occurs earlier during development, which may affect BMI until later childhood in a sex-specific manner.
The results emphasize the importance of early diagnosis and good control in ensuring a good outcome for patients with 21-hydroxylase deficiency.
There is evidence that exposure to perfluoroalkyl substances (PFAS) is associated with attention-deficit/hyperactivity disorder (ADHD) symptoms. Previous studies have focused on prenatal exposure to PFAS, and only few studies have examined the associations of early-childhood exposure, especially at low exposure levels. This study explored the association between early-childhood exposure to PFAS and ADHD symptoms later in childhood. In 521 children, we measured the serum levels of six PFAS in per
Ultrafine particles (UFP; particulate matter <0.1 μm in diameter) may be more harmful to human health than larger particles, but epidemiological evidence on their health effects is still limited. In this study, we examined the association between short-term exposure to UFP and mortality and hospital admissions in Copenhagen, Denmark. Daily concentrations of UFP (measured as particle number concentration in a size range 11-700 nm) and meteorological variables were monitored at an urban background
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