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이윤상 교수

Yun-Sang Lee

서울대학교 · 의학

연구실 소개

이 교수의 연구실은 공공조직의 인적 자원 관리와 조직 효과성에 초점을 맞추며, 퇴직 의지에 영향을 미치는 요인들인 '이탈', '목소리', '충성도'의 이론적 틀을 실증적으로 검토하고 있습니다. 동시에 자원기반관점(Resource-Based View)을 활용해 정부 기관의 효과성에 기여하는 행정, 인적, 재정, 정치적 자원의 역할을 분석하고 있습니다. 또한 방사성 약물 설계 및 면역세포 치료 기술 개발 분야에서도 활발한 연구를 진행하고 있으며, 간암 치료를 위한 새로운 방사성 약물과 CAR-T 세포 치료제의 임상적 응용 가능성을 모색하고 있습니다.

조직역동학공공기관 효율성방사성의약품CAR-T 치료의료신약개발

연구 현황

논문 수
177
총 인용 수
2,128
최근 5년 논문
60
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
60총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
117총합
20222023202420252026

주요 논문

15
1
논문|인용수 213·2007
Exit, Voice, Loyalty, and Pay: Evidence from the Public Workforce
Sang Yun Lee, Andrew B. Whitford
SJR Q1FWCI 7.9Journal of Public Administration Research and TheoryOA

We assess Hirschman's theory of exit, voice, and loyalty in the context of voluntary exit from organizations in the public workforce. Specifically, we test the effects of loyalty and voice on the likelihood a person states their intention to leave. We assess these relationships using data from the Federal Human Capital Survey. Our statistical analysis provides evidence that perceptions about voice and loyalty limit exit at all levels of the organizational hierarchy. Yet, dissatisfaction with pay

Public AdministrationSocial Sciences
2
논문|인용수 163·2012
Assessing the Effects of Organizational Resources on Public Agency Performance: Evidence from the US Federal Government
Sang Yun Lee, Andrew B. Whitford
SJR Q1FWCI 9.2Journal of Public Administration Research and TheoryOA

We assess the usefulness of a theory of organizations, the Resource-Based View, for the study of public agencies. We examine the differential impacts of an array of organizational resources (administrative, human, financial, physical, political, and reputation resources) on a core measure of federal agency effectiveness. Our analysis shows that certain types of resources have positive impacts on agency effectiveness, such as administrative (number of members in top governing structure), personne

Public AdministrationSocial Sciences
3
논문|인용수 37·2021
Mid‐term outcomes of the Pulsta transcatheter pulmonary valve for the native right ventricular outflow tract
Sang Yun Lee, Gi Beom Kim, Seong‐Ho Kim, So Ick Jang, Jae Young Choi, I‐Seok Kang, Young‐Hwue Kim
SJR Q1FWCI 4.1Catheterization and Cardiovascular InterventionsOA

A multi-center clinical trial was completed successfully with planned Pulsta valve implantation and demonstrated good mid-term effectiveness without device-related serious adverse events.

EpidemiologyMedicine
4
논문|인용수 29·2017
Preclinical Optimization of a CD20-specific Chimeric Antigen Receptor Vector and Culture Conditions
Sang Yun Lee, Philip Olsen, Dong Hoon Lee, Aimee L. Kenoyer, Lihua E. Budde, Shyril O’Steen, Damian J. Green, Shelly Heimfeld, Michael C. Jensen, Stanley R. Riddell, Oliver W. Press, Brian G. Till
SJR Q1FWCI 1.5Journal of ImmunotherapyOA

Chimeric antigen receptor (CAR)-based adoptive T-cell therapy is a highly promising treatment for lymphoid malignancies, and CD20 is an ideal target antigen. We previously developed a lentiviral construct encoding a third generation CD20-targeted CAR but identified several features that required additional optimization before clinical translation. We describe here several improvements, including replacement of the immunogenic murine antigen-binding moiety with a fully human domain, streamlining

OncologyMedicine
5
논문|인용수 27·2016
A prospective study on symptom generation according to spicy food intake and <scp>TRPV</scp> 1 genotypes in functional dyspepsia patients
Sang Yun Lee, Tatsuhiro Masaoka, Hye Seung Han, Juntaro Matsuzaki, Mi Jin Hong, Seiichiro Fukuhara, Hyemin Choi, Hidekazu Suzuki
SJR Q1FWCI 2.8Neurogastroenterology & Motility

Upper gastrointestinal symptoms are more common in subjects with a higher consumption of spicy foods, younger age and female gender, regardless of TRPV1 genotypes and the H. pylori infection status. Capsaicin-rich foods may induce stomach fullness.

GastroenterologyMedicine
6
논문|인용수 26·2023
CD8<sup>+</sup> chimeric antigen receptor T cells manufactured in absence of CD4<sup>+</sup> cells exhibit hypofunctional phenotype
Sang Yun Lee, Dong Hoon Lee, Wei Sun, Francisco Cervantes-Contreras, Ryan Basom, Feinan Wu, Si Liu, Richa Hirendra, Hamid Reza Mirzaei, Shyril O’Steen, Damian J. Green, Mazyar Shadman
SJR Q1FWCI 6.0Journal for ImmunoTherapy of CancerOA

Our data indicate that CD4<sup>+</sup> cell help during cell culture maintains robust CD8<sup>+</sup> CAR T cell function, with implications for clinical cell manufacturing.

OncologyMedicine
7
논문|인용수 23·2011
Clinical Significance of Thrombosis in an Intracardiac Blind Pouch After a Fontan Operation
Sang Yun Lee, Jae Suk Baek, Gi Beom Kim, Bo Sang Kwon, Eun Jung Bae, Chung Il Noh, Jung Yun Choi, Hong Kuk Lim, Woong‐Han Kim, Jeong Ryul Lee, Yong Jin Kim
SJR Q2FWCI 1.4Pediatric CardiologyOA

The univentricular heart after the Fontan operation may have a blind pouch formed by the pulmonary stump or rudimentary ventricle according to the anatomy before surgery. Thrombosis in an intracardiac blind pouch of patients with a univentricular heart is a hazardous complication. Because only a few reports have described this complication, the authors evaluated the clinical significance of thrombosis in an intracardiac blind pouch of a univentricular heart. They performed a retrospective review

EpidemiologyMedicine
9
논문|인용수 19·2019
Relation Between Exercise Capacity and Extracardiac Conduit Size in Patients with Fontan Circulation
Sang Yun Lee, Mikyoung Song, Gi Beom Kim, Eun-Jung Bae, Seong Ho Kim, So Ick Jang, Sung-Kyu Cho, Jae-Gun Kawk, Woong‐Han Kim, Chang‐Ha Lee, Hyun-Jeong Kim, Jayoun Kim
SJR Q2FWCI 1.3Pediatric Cardiology
EpidemiologyMedicine
10
논문|인용수 9·2013
Percutaneous Closure of the Acquired Gerbode Shunt Using the Amplatzer Duct Occluder in a 3-Month Old Patient
Sang Yun Lee, Jin Young Song, Jae Suk Baek
SJR Q2FWCI 1.0Korean Circulation JournalOA

The Gerbode shunt, known as the left ventricle to the right atrial communication, is a rather rare finding, following surgical closure of septal defects. Even though the surgical closure is accepted as a treatment of choice, we report a successful percutaneous transcatheter closure of the Gerbode shunt in a 3-months old baby who weighed 3 kilograms.

EpidemiologyMedicine
11
논문|인용수 8·2024
Decreased incidence of Kawasaki disease in South Korea during the SARS-CoV-2 pandemic
Kyung Jin Oh, Sang Yun Lee
SJR Q2FWCI 4.6Frontiers in PediatricsOA

After the start of the pandemic, the Kawasaki disease incidence decreased, and the percentage of patients with Kawasaki disease aged <1 year increased. These findings provide support for the hypothesis suggesting an infectious trigger in Kawasaki disease.

SurgeryMedicine
12
논문|인용수 7·2020
Changes in the Etiology and Clinical Characteristics of Pediatric Infective Endocarditis in South Korea
Seung Ha Song, Ji Seok Bang, Mi Seon Han, Ki Wook Yun, Sang Yun Lee, Mi Kyoung Song, Gi Beom Kim, Eun Jung Bae, Woong‐Han Kim, Eun Hwa Choi
SJR Q1FWCI 0.7The Pediatric Infectious Disease Journal

In South Korea, Gram-positive cocci represent 85% of all etiologic agents of IE in children with an increasing trend in the proportion of staphylococci.

EpidemiologyMedicine
13
논문|인용수 7·2024
The Long-term Outcomes and Risk Factors of Complications After Fontan Surgery: From the Korean Fontan Registry (KFR)
Sang Yun Lee, Soo‐Jin Kim, Chang‐Ha Lee, Chun Soo Park, Eun Seok Choi, Hoon Ko, Hyo Soon An, I‐Seok Kang, Ja Kyoung Yoon, Jae Suk Baek, Jae Young Lee, Jinyoung Song
SJR Q2FWCI 2.7Korean Circulation JournalOA

In Asian population with a high incidence of heterotaxy syndrome, the heterotaxy syndrome was identified as the poor prognostic factors for Fontan surgery. The preoperative low mPAP and less AVVR are associated with better early and long-term outcomes of Fontan surgery.

EpidemiologyMedicine
14
논문|인용수 7·2020
Changes of hospitalization trend in the pediatric cardiology division of a single center by increasing adult with congenital heart disease
Sang Yun Lee, Gi Beom Kim, Hye-Won Kwon, Mikyoung Song, Eun Jung Bae, Sungkyu Cho, Jae Gun Kwak, Hong‐Gook Lim, Woong‐Han Kim, Jeong-Ryul Lee
SJR Q2FWCI 0.3BMC Cardiovascular DisordersOA

The number of hospital cares for ACHD dramatically increased more than five times from 2005 to 2017. We need preparations for efficient healthcare for adults with CHD such as a multi-dimensional approach, effective communication, and professional training.

EpidemiologyMedicine
15
논문|인용수 6·2016
Linear X‐band GaN HEMT transformer‐based Doherty power amplifier
Sang Yun Lee, Junghoon Woo, S. Park, Youngwoo Kwon
SJR Q3FWCI 0.7Electronics Letters

An X‐band gallium‐nitride high electron mobility transistor (GaN HEMT) transformer‐based Doherty power amplifier (TBD PA) module with a phase lineariser has been developed. The TBD PA uses Cree's 6 W GaN HEMT bare die and realised in seven‐layer PCB. The proposed lineariser is employed before the TBD PA to compensate the phase distortion during the Doherty operation. The implemented TBD PA with 9.56 GHz continuous wave test shows a 38.5% power‐added efficiency at 39.6 dBm output power. Linearity

Electrical and Electronic EngineeringEngineering

대표 연구 분야

EpidemiologySurgeryPulmonary and Respiratory MedicineCardiology and Cardiovascular MedicineOncologySpeech and Hearing

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