최윤영 교수
Yun-Young Choi
서울대학교 · 의학
연구실 소개
최윤영 교수의 연구실은 소아기 질환, 특히 바이러스 감염과 관련된 급성 호흡기 질환의 역학적 특성과 임상 양상에 중점을 두고 있습니다. 특히 코로나19 패안기 동안 관찰된 옴리크론 변이에 따른 기도염증성 질환의 증가 추세를 분석하며, 소아 환자의 기도 폐쇄 및 호흡기 증상의 기전을 규명하고자 합니다. 또한, 임상 영상 소견과 생화학적 검사 간의 상호관계를 분석하여 악성 종양과 유사한 병변의 진단적 오류를 방지하고자 하는 영상의학 및 임상진단 연구도 진행 중입니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Croup is an acute upper respiratory disease primarily caused by the parainfluenza virus. Owing to inflammation and edema of the upper airways, children present with barky cough and stridor, and some may experience respiratory distress. We investigated children aged < 5 years with coronavirus disease 2019 (COVID-19) admitted to two hospitals in Seoul, South Korea, and observed a spike in croup cases during the omicron surge. Among the 569 children admitted from March 1, 2021 to February 25, 2022,
Hepatic masses detected by ultrasonography and computed tomography in a young woman showed increased radioactivity on F-18 fluorodeoxyglucose positron tomography. Those multiple hepatic lesions were investigated under suspicion of malignancy. Liver enzymes, viral markers, and tumor markers were in normal range. Ultrasonography-guided needle biopsy revealed to be focal fatty infiltration in the liver.
Highly suspecting BCG osteitis based on clinical manifestations is important for prompt management. A comprehensive national surveillance system is needed to understand the exact incidence of serious adverse reactions following BCG vaccination and establish safe vaccination policy in Korea.
본 연구에서는 선행연구들을 근거로 불안전 애착이 스마트폰 중독에 영향을 미치는 영향을 충동성이 매개하고, 이 과정을 사회적 지지가 조절하는지 살펴보았다. 이를 위해 서울, 경남지역 4개 대학에 재학 중인 대학생과 온라인을 통해 설문을 실시하였고 연구에 참여한 대학생 431명 중 설문에 성실히 응답한 361명으로부터 얻은 자료를 분석에 활용하였다. 본 연구의 조절된 매개모형은 Preacher, Rucker와 Hayes(2007)가 제안한 모형을 근거로 설정하여 부트스트랩 절차를 통해 매개효과의 유의성을 검증하였고 Ping(1996)의 2단계 추정법에 따라 조절효과 및 조절된 매개효과의 유의성을 검증하였다. 본 연구의 조절된 매개모형은 자료에 적합하였고 조절된 매개효과는 일부 지지되었다. 첫째, 매개효과 검증 결과 애착불안과 애착회피는 충동성을 통해 스마트폰 중독에 간접적으로 영향을 미치는 것으로 나타났다. 둘째, 조절효과 검증 결과 사회적 지지는 애착불안과 충동성의 관계만 조절하였다.
BNT162b2 vaccination was tolerable among adults who were ≥ 75 years of age.
Subgraph matching is the problem of searching for all embeddings of a query graph in a data graph, and subgraph query processing (also known as subgraph search) is to find all the data graphs that contain a query graph as subgraphs. Extensive research has been done to develop practical solutions for both problems. However, the existing solutions still show limited query processing time due to a lot of unnecessary computations in search. In this paper, we focus on exploring as compact search spac
This study investigated the dose- and time-dependent effects of caffeine consumption throughout puberty in peripubertal rats. A total of 85 male SD rats were randomly divided into four groups: control and caffeine-fed groups with 20, 60, or 120 mg/kg/day through oral gavage for 10, 20, 30, or 40 days. Caffeine decreased body weight gain and food consumption in a dose- and time-dependent manner, accompanied by a reduction in muscle and body fat. In addition, it caused a shortening and lightening
We used data from seven freeways in South Korea to evaluate the safety impact of four safety countermeasures: (1) automated speed enforcement cameras, (2) chevron signs, (3) delineator posts, and (4) shoulder rumble strips. The evaluation was based on crash data from 2001 to 2008 and provided three years of before data and three years of after data for each countermeasure. We developed crash modification factors (CMFs) to show the safety impact of the countermeasures. We used the empirical Bayes
Background: Mycobacterium bovis Bacille Calmette-Guérin (BCG) osteitis, a rare complication of BCG vaccination, has not been well investigated in Korea. This study aimed to evaluate the clinical characteristics of BCG osteitis during the recent 10 years in Korea. Methods: Children diagnosed with BCG osteitis at the Seoul National University Children's Hospital from January 2007 to March 2018 were included. M. bovis BCG was confirmed by multiplex polymerase chain reaction (PCR) in the affected bo
Plain radiographs of a 68-year-old man with lower back pain showed degenerative changes in the lumbar spine. An MRI showed a herniated disc at L5-S1 and an unexpected lesion in the L1 body suggesting a possible malignancy. Lumbar SPECT showed slightly decreased uptake in L1. Therefore, a benign condition such as a hemangioma was entertained as a possibility. Tc-99m RBC SPECT showed increased uptake in L1, suggesting the possibility of a vertebral hemangioma. A CT scan of the lumbar spine showed
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