东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Yoshihiro Kamada's research lab specializes in magnetic fusion energy, focusing on advanced tokamak plasma physics and reactor-relevant operation scenarios. The lab investigates high-confinement plasma regimes, pedestal stability, and ELM (edge localized mode) control to enable steady-state and high-performance fusion operations. Key research directions include optimizing plasma shaping, bootstrap current fraction, and integrated performance in devices like JT-60U and JT-60SA, with direct relevance to ITER and DEMO reactor development. The lab also explores edge plasma behavior, MHD stability, and advanced plasma control techniques using multiple actuators such as heating, current drive, and resonant magnetic perturbations.
Professor Tomoaki Kudo's research lab specializes in endovascular and hybrid surgical interventions for aortic arch pathologies, with a primary focus on optimizing thoracic endovascular aortic repair (TEVAR) outcomes. The lab investigates proximal landing zone selection to prevent complications such as type 1a endoleak and bird-beak deformity, emphasizing precise preoperative imaging and patient-specific stent graft design. A key research direction involves minimizing postoperative stroke through rigorous atheroma evaluation and innovative techniques like hypoxic preconditioning of peripheral blood mononuclear cells to enhance therapeutic angiogenesis in limb ischemia. The lab also explores the feasibility and long-term safety of total endovascular aortic arch repair using custom-made branched endografts in high-risk surgical candidates.
Professor Haruna Yamasawa's research lab specializes in indoor air quality and ventilation engineering, focusing on innovative air distribution systems such as impinging jet ventilation (IJV). The lab investigates the fundamental fluid dynamics and thermal performance of IJV under various conditions, including heating, cooling, and obstacle-affected environments, to enhance thermal comfort and contaminant control. Their work combines full-scale experiments, CFD simulations, and theoretical modeling to develop predictive models for temperature and contaminant distribution.
Professor Hitoshi Kasai's research lab specializes in the design, synthesis, and characterization of organic micro- and nanocrystals with tailored optical and electronic properties. The lab focuses on developing advanced reprecipitation techniques to control the size and morphology of organic semiconductors—particularly perylene-based materials—enabling precise tuning of their excitonic behavior. A key research direction involves understanding size-dependent excitonic phenomena, such as blue-shifted absorption and enhanced free-exciton luminescence in sub-200 nm crystals, which has implications for optoelectronic devices and biomedical applications. The lab also pioneers the fabrication of water-dispersible nanoparticles of biologically active compounds, such as SN-38, for improved drug delivery and therapeutic efficacy.
Professor Kanako Nozawa-Kumada's research lab specializes in the development of innovative, transition-metal-free, and environmentally friendly methods for C–H bond functionalization and oxidative transformations. Her group focuses on designing efficient catalytic systems—particularly using copper, peroxides, and silyl reagents—for the selective synthesis of valuable heterocyclic scaffolds such as isoindolinones, β-lactams, and lactones. The lab emphasizes atom-economical, mild, and functional group-tolerant processes that avoid expensive or toxic reagents, aligning with green chemistry principles. Their work also extends to the synthesis of bioactive molecules, including retinoid analogs, through selective C–H silylation and functionalization strategies.
Professor Kinya Toriyama's research lab focuses on the molecular mechanisms underlying cytoplasmic male sterility (CMS) and fertility restoration in higher plants, particularly in rice and Arabidopsis. The lab investigates the roles of nuclear-encoded pentatricopeptide repeat (PPR) proteins in post-transcriptional regulation of mitochondrial transcripts, including RNA processing, splicing, and stability, which are critical for male gametophyte development. A central theme is understanding how PPR genes restore fertility in CMS plants by modulating the expression or accumulation of cytotoxic mitochondrial proteins such as ORF79. The lab also explores the regulation of tapetum-specific programmed cell death (PCD) and its impact on microsporogenesis, linking cellular death pathways to reproductive development.
Professor Fumitaka Osakada's research lab focuses on neural regeneration and stem cell biology, with a central emphasis on understanding and manipulating endogenous retinal glial cells (Müller glia) to regenerate lost retinal neurons. The lab investigates molecular mechanisms—particularly Wnt/beta-catenin signaling—that drive the dedifferentiation and proliferation of Müller glia after injury or degeneration. Using induced pluripotent stem cells (iPSCs) and defined chemical differentiation protocols, the lab develops strategies for generating retinal cell types such as photoreceptors and retinal pigment epithelium for regenerative therapies. Additionally, the lab employs advanced viral tracing techniques to map neural circuits, linking structural connectivity with functional outcomes in the central nervous system.
Professor Itaru Kushima's research lab focuses on the genetic underpinnings of neuropsychiatric disorders, particularly schizophrenia. The lab investigates rare genetic variants, such as missense mutations in the KALRN gene, to understand their role in disease susceptibility. Using advanced genomic and bioinformatic approaches, the team aims to uncover novel genetic risk factors and molecular mechanisms contributing to psychiatric illnesses. Their work bridges population genetics with neurobiology to advance precision medicine in mental health.
Professor Chairunnisa's research lab specializes in sustainable materials development with a focus on converting local biomass waste into high-performance functional materials for environmental and energy applications. Key research directions include the design of microporous activated carbons from agricultural residues—such as acorn nutshells—for thermal energy storage and desiccant dehumidification, emphasizing low-temperature regeneration and enhanced water vapor uptake. The lab also explores bioactive compounds from natural sources, such as cinnamon oil, for antimicrobial applications, particularly against drug-resistant pathogens. Overall, the lab integrates green synthesis, materials characterization, and application-driven innovation to address challenges in energy efficiency and public health.
Professor Ken Natsuga's research lab focuses on the molecular and cellular mechanisms underlying blistering skin diseases, particularly autoimmune bullous disorders such as bullous pemphigoid and hereditary epidermolysis bullosa. The lab investigates the roles of key structural proteins like type XVII collagen (COL17) and plectin in maintaining epidermal integrity, stem cell niche regulation, and disease pathogenesis. Using humanized mouse models, patient-derived cells, and genetic analyses, the lab aims to identify precise autoantigenic epitopes and understand the pathophysiology of barrier dysfunction in ichthyoses and related genodermatoses.
Professor Hideko Koshima's research lab specializes in stimuli-responsive materials, particularly photomechanical crystals and supramolecular chemistry. The lab investigates the design and behavior of organic crystals that undergo controlled mechanical motion—such as bending or twisting—under light irradiation, focusing on mechanisms like photoisomerization and photothermal effects. A key research direction involves understanding polymorphism and molecular packing in salicylideneaniline derivatives to tailor their actuation responses. Additionally, the lab explores crown ether-based extraction systems for selective metal ion recognition and separation, especially in acidic media.
Professor Siro Simizu's research lab focuses on the molecular mechanisms underlying cancer progression, particularly the roles of key enzymes and signaling molecules in tumor invasion, metastasis, and cell death. The lab investigates proteases such as heparanase and RECK, exploring how post-translational modifications like glycosylation influence their function in extracellular matrix degradation and tumor suppression. A central theme is the involvement of reactive oxygen species, especially hydrogen peroxide, in apoptosis signaling induced by anticancer agents. The lab also examines structural and functional regulators of vasculogenic mimicry, such as integrin β1, highlighting novel therapeutic targets in aggressive cancers.
Professor Woosub Roh's research lab specializes in cloud-system-resolving modeling and satellite-based evaluation of tropical and mid-latitude cloud systems, with a focus on improving the representation of cloud microphysics and precipitation processes. The lab develops and evaluates advanced cloud microphysics schemes using high-resolution global models such as NICAM, combined with multi-sensor satellite observations and satellite simulators. Key research directions include the quantitative evaluation of cloud phase, echo-top height, and precipitation using data from TRMM, CALIPSO, and EarthCARE, as well as the development of novel retrieval and evaluation techniques for deep convective systems. The lab also investigates the impact of model resolution and microphysical parameterizations on the simulation of cloud systems and radiative fluxes.
Professor Takeaki Ozawa's research lab specializes in developing innovative protein engineering and imaging technologies for real-time, in vivo monitoring of cellular processes. The lab focuses on leveraging protein splicing systems—particularly those based on inteins like DnaE and VDE—to enable sensitive detection of protein-protein interactions and subcellular protein trafficking in living cells. A central theme is the reconstitution of functional fluorescent or luminescent proteins through split-intein-mediated self-assembly, allowing non-invasive visualization of dynamic biological events such as circadian clock regulation and stress responses. The lab also applies these tools to study disease-relevant pathways, including oxidative stress and protein homeostasis.
Professor Bingchao Zhang's research lab specializes in fluid dynamics and wind engineering, with a focus on numerical simulation and data-driven analysis of turbulent flows around buildings and urban structures. The lab employs advanced techniques such as large eddy simulation (LES), spectral proper orthogonal decomposition (SPOD), and extended SPOD (ESPOD) to extract coherent flow structures and quantify their contributions to wind loads and pressure distributions. Research also extends to agricultural engineering, particularly in the design of automated systems for seedling handling using fluidic actuation principles. The lab integrates computational fluid dynamics with real-world applications, from urban wind environment assessment to sustainable agricultural machinery development.
Professor Yuji Suzuki's research lab specializes in microelectromechanical systems (MEMS) and energy harvesting technologies, with a strong focus on developing miniaturized, efficient, and robust devices for low-power electronics. The lab pioneers innovative electret-based MEMS devices, including vibration and rotational energy harvesters, that leverage electrostatic forces and novel structural designs to enable passive, maintenance-free power generation. Key research directions include bistable energy harvesters for broadband operation, electret-based electrostatic levitation to prevent stiction, and advanced MEMS fabrication for applications in wireless sensors and structural health monitoring. The lab also explores fluidic applications, such as riblet surface effects on turbulent flows, demonstrating interdisciplinary expertise in both microsystems and fluid dynamics.
Professor Shigeo Murata's research lab focuses on the molecular mechanisms of the ubiquitin-proteasome system, particularly the structure and function of proteasomes and their regulatory complexes in immune surveillance and cellular homeostasis. The lab investigates how specialized proteasome subunits, such as beta5t and PA28gamma, regulate peptide generation for antigen presentation in the immune system, with a strong emphasis on thymic selection and T cell development. Using genetically engineered mouse models, the lab explores the physiological roles of these proteasome components in health and disease. Their work bridges structural biology, immunology, and molecular genetics to uncover fundamental principles of intracellular protein degradation and immune recognition.
Professor Takahiko Moteki's research lab specializes in the design and synthesis of advanced porous materials, particularly zeolites and mesoporous silica, with a focus on topotactic transformations from layered precursors. The lab explores novel catalytic materials for sustainable chemical transformations, including methane conversion to oxygenates and ethanol upgrading via Guerbet-type reactions. A key research direction involves controlling framework topology, porosity, and surface chemistry to enable selective catalysis and gas separation, such as hydrogen purification using microporous sodalite materials. The lab combines in situ spectroscopy, isotope labeling, and advanced synthesis techniques to elucidate reaction mechanisms at the molecular level.
Professor Hidetoshi Omiya's research lab specializes in theoretical high-energy and gravitational physics, focusing on ultra-light scalar fields—particularly axions—and their astrophysical implications. The lab investigates the dynamics of axion condensates around rotating black holes, especially through superradiant instability and nonlinear self-interaction effects, which can lead to observable gravitational wave signals. A key direction involves developing advanced numerical and analytical methods, such as the dynamical renormalization group approach, to model the non-linear evolution of these quantum condensates without restrictive approximations. The lab also explores gravitational wave detection prospects, particularly with future space-based detectors like LISA-Taiji, to probe fundamental physics beyond the Standard Model.
Professor Satoshi Ninagawa's research lab focuses on the molecular mechanisms of endoplasmic reticulum-associated degradation (ERAD), particularly the quality control of misfolded glycoproteins and non-glycoproteins in the endoplasmic reticulum. The lab employs advanced genome editing technologies, such as TALEN and the DT40 chicken cell system, to dissect the roles of key ERAD components, including EDEM family proteins and SEL1L, in glycoprotein and protein degradation. A central theme is understanding the enzymatic functions of EDEMs—specifically their mannosidase activity in mannose trimming during ERAD—and how these processes relate to human diseases such as diabetes and schizophrenia. The lab also investigates the impact of psychotropic drugs, like olanzapine, on cellular protein processing, particularly insulin biosynthesis and secretion.
