东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Ryo Tazaki's research lab specializes in theoretical and computational astrophysics, focusing on the radiative and dynamical properties of dust aggregates in planet-forming environments. The lab investigates how complex-shaped, porous dust particles—formed through coagulation in protoplanetary disks—affect light scattering, polarization, and radiative transfer. Using advanced numerical methods such as the T-matrix and radiative torque alignment theories, the group aims to bridge the gap between observational data (e.g., from ALMA) and the physical properties of primordial dust, including monomer size, porosity, and fractal structure. Their work is pivotal in decoding the early stages of planet formation through polarimetric and scattering signatures of dust.
Professor Hokuto Ohtsuka's research lab focuses on the molecular mechanisms underlying chronological lifespan regulation in fission yeast (*Schizosaccharomyces pombe*), with a central emphasis on the Ecl1 family of small proteins and their roles in stress resistance, metabolic adaptation, and developmental transitions. The lab investigates how nutrient sensing pathways—particularly those involving sulfur and zinc—interact with key regulators like the Zip1 transcription factor and Ecl1 family genes to extend lifespan. Their work also explores the evolutionary conservation and functional overlap of these genes across yeast species, linking cellular homeostasis to longevity and stress resilience. The lab integrates molecular genetics, cell biology, and systems-level analysis to uncover fundamental principles of cellular aging and survival under nutrient stress.
Professor T. Kaneyoshi's research lab specializes in theoretical magnetism, focusing on the magnetic properties of low-dimensional and nanostructured materials using advanced statistical mechanics approaches. The lab investigates phase transitions, critical phenomena, and magnetization behaviors in Ising spin systems, particularly in nanowires, nanotubes, and surfaces with nonmagnetic doping or dilution. Key research directions include the development of effective-field theories with correlations to model spin interactions and many-body effects, with applications to real materials such as molecular-based magnets and ferrimagnetic systems. The work emphasizes the role of surface effects, crystal-field interactions, and anisotropy in determining complex magnetic responses like compensation points and tricritical behavior.
Professor Makoto Murata's research lab specializes in hematopoietic stem cell transplantation and immunotherapy, with a focus on improving outcomes in allogeneic transplantation. Key research directions include identifying novel minor histocompatibility antigens, optimizing cord blood transplantation through cell dose and engraftment strategies, and evaluating mesenchymal stem cell therapy for steroid-refractory graft-versus-host disease. The lab also investigates epigenetic modulators, such as histone deacetylase inhibitors, in hematological malignancies, bridging basic science with clinical applications in transplantation and oncology.
Professor Junichi Ikenouchi's research lab focuses on the molecular mechanisms underlying epithelial cell polarity and junctional complex formation, particularly the biogenesis and regulation of tight junctions (TJs) and adherens junctions (AJs). The lab investigates key proteins such as tricellulin, claudins, and ZO-1, elucidating their roles in barrier function, junctional organization, and epithelial morphogenesis. Using advanced cell biological and molecular approaches, the lab explores signaling pathways involving small GTPases (e.g., Rac1, Arf6) and polarity complexes (e.g., Par-3/Par-6/aPKC) in epithelial polarization and disease-related junctional defects. Their work provides fundamental insights into epithelial barrier integrity and its implications in development and cancer.
Professor Kenji Yasuoka's research lab specializes in molecular-scale simulations of phase transitions, nucleation, and transport phenomena in soft matter and nanofluidic systems. The lab focuses on understanding the dynamics of vapor-liquid transitions, including homogeneous and heterogeneous nucleation, evaporation, and condensation, using advanced molecular dynamics and dissipative particle dynamics simulations. A key emphasis is placed on the interplay between thermodynamics and kinetics in cluster formation, as well as the role of confinement and external fields in enhancing separation processes, such as water–methanol separation in carbon nanotubes. The lab also investigates the interaction of nanoparticles with biological membranes, particularly in the context of vesicle translocation and cellular uptake mechanisms.
Professor M Matsuzaki's research lab specializes in cardiovascular and neuroscience research, focusing on the mechanisms of myocardial ischemia and reperfusion in animal models, particularly in conscious dogs with chronic coronary stenosis. The lab also pioneers advanced in vivo imaging techniques, such as two-photon microscopy with genetically encoded calcium indicators, to study neuronal activity and cortical circuitry in awake, behaving primates, including common marmosets. Their work integrates physiological measurements, molecular imaging, and behavioral training to investigate cardiac function and neural dynamics at high spatial and temporal resolution. The lab is particularly known for developing long-term, stable expression systems for calcium indicators and for enabling chronic two-photon imaging in primate cerebral cortex.
Professor Yoshimasa Kawazoe's research lab specializes in medical artificial intelligence, focusing on the development and application of deep learning and natural language processing techniques for clinical data. The lab pioneers domain-specific pre-trained language models for Japanese medical text, enhances pathology image analysis using convolutional neural networks, and explores semantic interoperability in healthcare data through standards like HL7 and RDF. Their work bridges clinical informatics, AI, and electronic health records to improve diagnostic accuracy, clinical decision support, and data usability in hospital systems.
Professor Jongseong Gwak's research lab specializes in human-centered environmental design, focusing on the interplay between physiological responses, cognitive states, and environmental factors such as thermal conditions and vehicle dynamics. The lab investigates how thermal comfort, driver arousal, and drowsiness can be monitored and optimized through integrated sensing of physiological signals, behavioral metrics, and driving performance. A key research direction involves developing real-time detection systems for early drowsiness in drivers using hybrid sensing modalities, with applications in intelligent transportation and advanced driver assistance systems. The lab also explores human-machine interaction in automated driving systems, particularly in enhancing safety and user acceptance through effective HMI design.
Professor Yasushi Yamaguchi's research lab specializes in geometric modeling, visualization of distributed systems, and advanced cryptography with a focus on human-centric computing and intuitive user interaction. The lab explores nonmanifold topology for robust 3D modeling, develops scalable and reactive visualization techniques like 'Data Jewelry Box' for time-varying data, and advances visual cryptography for secure, human-decryptable image sharing—particularly for continuous-tone images. A recurring theme is enhancing user experience through intelligent modeling history mechanisms and robust, visually intuitive systems.
Professor Shinichi Sato's research lab focuses on the immunological mechanisms underlying systemic sclerosis (SSc), with a central emphasis on the role of CD19 in regulating B cell signaling thresholds and its contribution to autoimmunity and fibrosis. The lab investigates how dysregulated CD19 expression leads to B cell hyperresponsiveness, autoantibody production, and pathological remodeling in SSc, integrating findings from transgenic mouse models and patient studies. Additional research explores the involvement of fibrogenic mediators like CTGF and chemokines such as MCP-1 and MIP-1α in disease progression. The lab aims to identify novel therapeutic targets by dissecting the interplay between immune dysregulation and fibrotic tissue damage in SSc.
Professor Tetsuya Takemi's research lab specializes in atmospheric dynamics and cloud physics, with a focus on tropical convection, mesoscale weather systems, and severe weather phenomena such as typhoons, squall lines, and dust storms. The lab investigates the roles of environmental thermodynamics, moisture profiles, and atmospheric stability in modulating deep convection and precipitation extremes, particularly in East Asia and the western Pacific. Using high-resolution numerical modeling (e.g., WRF), observational analysis, and advanced turbulence and microphysics schemes, the lab explores how subgrid processes and terrain effects influence the development and intensity of hazardous weather events.
Professor Yutaka Satou's research lab focuses on the molecular and genomic mechanisms underlying chordate evolution and development, with a central emphasis on the ascidian Ciona intestinalis as a model organism. The lab investigates the genetic basis of key chordate innovations—such as notochord formation, heart specification, and neural development—by integrating genomics, functional analysis, and comparative biology. By leveraging high-quality genomic and transcriptomic resources, including cDNA clones, ESTs, and genome databases, the lab aims to decipher the regulatory networks governing early embryogenesis and the evolution of vertebrate complexity from simple chordate ancestors. Their work provides critical insights into the origins of chordate body plans and the genetic toolkit underlying vertebrate evolution.
Professor Yuki Kurashige's research lab specializes in advanced quantum chemical methods for strongly correlated electron systems, with a focus on multireference electronic structure theories. The lab develops and applies cutting-edge computational techniques such as the density matrix renormalization group (DMRG) and its extensions to address challenging problems in quantum chemistry, including accurate treatment of static and dynamical electron correlation in large active spaces. Key research directions include the integration of DMRG with perturbation theory (e.g., DMRG-CASPT2), efficient implementations for transition metal compounds and excited states, and novel ansätze for full-CI accuracy using unitary coupled cluster and Jastrow-type correlations. The lab emphasizes algorithmic innovation, parallelization, and application to complex molecular systems such as chromophores and transition metal dimers.
Professor Tomokazu Umeyama's research lab specializes in the design and development of advanced nanomaterials for sustainable energy conversion, with a focus on artificial photosynthesis and solar energy applications. The lab explores the integration of carbon nanomaterials—such as single-walled carbon nanotubes, fullerenes, and graphene—with conjugated polymers and porphyrin-based semiconductors to create efficient, hybrid photoactive systems. Key research directions include the synthesis of covalent and supramolecular nanocarbon-porphyrin hybrids, optimization of charge transfer dynamics, and the engineering of nanostructured heterojunctions for high-performance organic and perovskite solar cells.
Professor Sendong Ren's research lab specializes in advanced joining technologies for lightweight hybrid structures, with a primary focus on dissimilar material joining between aluminum alloys and carbon-fiber-reinforced plastics (CFRP). The lab develops innovative processes such as coaxial one-side resistance spot welding (COS-RSW) and employs advanced numerical modeling using in-house finite element codes (e.g., JWRIAN, JWRIAN-SPOT) to simulate multi-physics phenomena including thermal, electrical, and mechanical coupling. The integration of digital twin technology, artificial intelligence (e.g., multi-task learning-based ANN), and experimental validation enables real-time prediction and optimization of welding parameters and joint performance.
Professor Kazufumi Nomura's research lab specializes in advanced welding process monitoring and control, focusing on real-time quality assessment using non-contact sensing techniques. The lab develops innovative methods combining machine learning, laser ultrasonics, and plasma diagnostics to monitor and predict welding integrity during high-temperature operations. Key research directions include deep learning-based prediction of weld penetration and burn-through, three-dimensional temperature measurement of asymmetric arc plasmas, and in-process detection of defects such as solidification cracks using laser ultrasonic testing. The lab aims to enhance manufacturing efficiency, reliability, and automation in industrial arc welding processes.
Professor Shengfang Shi's research lab specializes in the design and fabrication of multifunctional ceramic-metal and ceramic-cermet composites with tailored mechanical, electrical, and self-healing properties. The lab focuses on enhancing fracture toughness and electrical conductivity in alumina-based composites through in-situ synthesis, microstructural control, and the introduction of reactive elements such as titanium, tungsten, titanium carbide, and cerium oxide. A key innovation is the development of room-temperature crack-healing functionality via electrochemical anodization, enabling structural recovery and improved reliability of advanced ceramics. The lab's work bridges fundamental materials science with practical applications in structural electronics and durable engineering components.
Professor Mikio Fukuhara's research lab specializes in the ultrasonic characterization of advanced materials, focusing on the temperature-dependent elastic and viscoelastic properties of metals, ceramics, semiconductors, and biopolymers. The lab employs high-precision ultrasonic pulse sing-around techniques to investigate internal friction, wave velocity, and elastic moduli, providing insights into phase transitions, microstructural evolution, and atomic-scale dynamics. Key research directions include the coupling of electronic and lattice degrees of freedom in superconductors, the role of defects and grain boundaries in mechanical behavior, and the development of novel energy storage materials such as cellulose nanofiber-based supercapacitors.
Professor Shigeki Suzuki's research lab focuses on molecular and cellular mechanisms underlying periodontal tissue homeostasis, inflammation, and regeneration. Key research directions include the role of transcriptional regulators like PPARγ in periodontal ligament fibroblasts, the pathogenesis of chronic periodontitis through genetic and epigenetic factors, and the identification of bioactive molecules such as DPIT and heparin-LL37 complexes in modulating immune responses and antimicrobial defense. The lab also investigates extracellular matrix proteins like phosphophoryn and their roles in dental hard tissue formation and repair.
