东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Yuichi Kuya's research lab specializes in experimental and computational fluid dynamics, with a focus on flow control and aerodynamic optimization in complex configurations such as racing car wings and turbulent boundary layers. The lab investigates vortex generator applications for separation control in ground effect flows, combining wind tunnel experiments, surface and off-surface flow measurements, and high-fidelity simulations. Innovative approaches such as multifidelity surrogate modeling and quantum annealing-based lattice-gas automata are also explored to enhance computational efficiency and physical fidelity in flow prediction. The lab emphasizes interdisciplinary methods, integrating design of experiments, advanced diagnostics, and emerging quantum computing techniques for fluid dynamics.
Professor Eriko Nango's research lab specializes in time-resolved structural biology, focusing on visualizing ultrafast protein dynamics at atomic resolution using advanced X-ray techniques such as serial femtosecond crystallography at X-ray free electron lasers. The lab investigates conformational changes in membrane proteins, enzymes, and G-protein coupled receptors to understand fundamental mechanisms of biological function, including proton pumping, enzyme catalysis, and taste signal transduction. By combining innovative perturbation methods—such as temperature jump and mechanism-based inhibitors—the lab uncovers the choreography of structural motions that drive complex biological processes. Their work bridges the gap between protein dynamics and function, offering insights with implications for drug design and synthetic biology.
Professor Kenji Fujimori's research lab specializes in radiopharmaceuticals and molecular imaging, focusing on the pharmacokinetics and biodistribution of monoclonal antibodies and their radiolabeled conjugates in cancer and critical care settings. The lab integrates mathematical modeling with clinical data to optimize radioimmunotherapy dosimetry, emphasizing both macroscopic organ distribution and microscopic tumor penetration dynamics. A key research direction involves improving patient selection for therapies such as PMX (hemoperfusion with polymyxin B) in septic shock by analyzing clinical database correlations with disease severity scores. The lab also advances diagnostic imaging techniques, particularly SPECT/CT fusion imaging, for precise localization of gastrointestinal bleeding.
Professor Quan Manh Phung's research lab specializes in the development and application of advanced multiconfigurational quantum chemistry methods to accurately describe the electronic structures of first-row transition metal complexes. The lab focuses on challenging problems involving near-degeneracy electronic states, spin crossover phenomena, and reaction mechanisms in bioinorganic systems such as cytochromes P450 and hydrogenases. By combining multiconfigurational perturbation theory (CASPT2) with powerful solvers like the density matrix renormalization group (DMRG), the lab achieves high-accuracy descriptions of complex electronic behavior in systems with strong electron correlation and static correlation effects. Their work also involves benchmarking and improving density functional theory and local correlation methods against highly accurate wavefunction-based references.
Professor Yuichi Ishikawa's research lab specializes in molecular oncology and hematology, focusing on the genetic and molecular mechanisms underlying hematological malignancies, particularly acute myeloid leukemia (AML) and renal cell carcinoma. The lab investigates driver mutations such as KIT and FLT3 in AML, explores pharmacokinetic and pharmacodynamic factors affecting treatment response, and examines rare genetic alterations like the t(6;11) translocation in TFEB-related renal cell carcinoma. A central theme is the identification of molecular biomarkers and resistance mechanisms to improve risk stratification and therapeutic outcomes in leukemia and solid tumors.
Professor Nobuhiro Hata's research lab specializes in molecular oncology and neuro-oncology, focusing on the genetic and molecular mechanisms underlying gliomas and other central nervous system tumors. The lab investigates tumor tropism, particularly the role of growth factors like PDGF-BB in guiding human mesenchymal stem cells (hMSCs) to gliomas, with translational applications in cell-based therapies. A key focus is also on clinical molecular diagnostics, including high-resolution melting (HRM) analysis for detecting mutations in IDH1, IDH2, and BRAF, aiming to improve precision in glioma classification and treatment. The lab contributes to advancing personalized medicine through biomarker discovery, such as MGMT and CDKN2A status, and their impact on prognosis and response to therapies like bevacizumab.
Professor Koki Aizawa's research lab specializes in geophysical exploration using magnetotelluric (MT) methods to investigate subsurface electrical structures in active volcanic and tectonically active regions. The lab focuses on understanding hydrothermal systems, crustal fluid pathways, and magma dynamics through high-resolution 3D resistivity modeling derived from broadband MT and telluric data. Their work integrates geophysical observations with geological and volcanic processes, contributing to hazard assessment and insights into Earth's deep fluid cycles. Recent studies also explore the geoelectrical signatures of volcanic lightning and their implications for atmospheric and planetary processes.
Professor Yu Matsuda's research lab specializes in advanced optical measurement techniques and functional materials for fluid dynamics and chemical sensing. The lab focuses on developing innovative pressure- and temperature-sensitive paints (PSP/TSP) with enhanced response speed, photostability, and applicability in complex flow environments. Key research directions include sensor optimization using machine learning and modal analysis, novel paint formulations using polymer particles to mitigate photocatalytic degradation, and hybrid data analysis methods for single-particle tracking in heterogeneous media. The lab also pioneers low-cost, printable electronic components for paper-based analytical devices, expanding their functionality in point-of-care diagnostics and microfluidic systems.
Professor Tsubasa Takizawa's research lab focuses on the neuroimmunological mechanisms underlying migraine and brain injury, with a particular emphasis on cortical spreading depolarization (CSD) and its role in triggering inflammatory responses in the brain. The lab employs innovative optogenetic and minimally invasive techniques to study CSD in vivo, exploring how neuronal hyperexcitability and danger-associated molecular patterns (e.g., HMGB1) contribute to neuroinflammation and migraine pathophysiology. Additionally, the lab investigates clinical aspects of migraine, including treatment efficacy of anti-CGRP therapies like galcanezumab and the impact of external triggers such as vaccinations or novel drugs (e.g., BCG) on migraine onset and progression.
Professor Sze Yun Set's research lab specializes in nanomaterials-based photonics, with a primary focus on the development and application of carbon nanotube-based saturable absorbers for ultrafast fiber lasers. The lab explores novel mode-locked laser systems, particularly in the mid-infrared and 2 μm wavelength regions, emphasizing high-speed, robust, and cost-effective optical pulse generation. Key research directions include the design of all-fiber lasers, dissipative soliton dynamics, and advanced optical characterization techniques for photonic devices.
Professor Ryo Terao's research lab focuses on the molecular mechanisms underlying age-related ocular diseases, particularly age-related macular degeneration (AMD) and retinal vascular disorders. The lab investigates key pathways involving cellular senescence, NAD+ metabolism, lipid mediators such as sphingosine 1-phosphate (S1P), and cholesterol homeostasis in retinal pigment epithelial cells and macrophages. A central theme is the interplay between metabolic stress, inflammation, and angiogenesis in driving retinal degeneration and neovascularization. The lab also explores therapeutic strategies targeting these pathways, including NAD+ supplementation and modulation of S1P signaling.
Professor Yoshiaki Ono's research lab specializes in high-redshift galaxy evolution, focusing on the physical properties, stellar populations, and morphologies of distant galaxies observed in the early universe. Using deep multi-wavelength imaging and spectroscopy from Hubble and James Webb Space Telescopes, the lab investigates Lyman-alpha emitters and dropout galaxies at redshifts z ≈ 3–11 to understand early star formation, galaxy assembly, and reionization. The lab combines advanced photometric and spectroscopic techniques with detailed SED modeling and morphological analysis to probe the rest-frame UV to infrared properties of these primordial systems.
Professor Kazuo Chin's research lab specializes in sleep medicine and respiratory physiology, with a primary focus on obstructive sleep apnea syndrome (OSAS) and its systemic complications. The lab investigates the impact of OSAS on metabolic and coagulation profiles, particularly examining biomarkers such as leptin, fibrinogen, and inflammatory markers, and evaluates the therapeutic benefits of non-invasive ventilation like NCPAP. Research also explores the epidemiological links between OSAS, metabolic syndrome, and cardiovascular risk, especially in relation to circadian patterns and treatment outcomes. The lab integrates clinical studies with ultrasound-guided interventions to improve diagnostic accuracy and patient safety in regional anesthesia.
Professor Shotaro Hiraide's research lab specializes in the design and application of flexible metal-organic frameworks (MOFs) and porous coordination polymers for advanced gas separation and storage technologies. The lab focuses on understanding and harnessing unique phenomena such as gate-opening adsorption, intrinsic thermal management, and temperature-dependent sorption behavior to develop energy-efficient, high-performance adsorbents. Their work bridges molecular-level simulations with experimental validation, aiming to optimize materials for real-world processes like pressure vacuum swing adsorption (PVSA) and non-isothermal adsorption systems.
Professor Ryoma Sato's research lab specializes in the theoretical foundations of graph neural networks (GNNs), focusing on enhancing their expressive power and algorithmic capabilities for combinatorial optimization problems. The lab investigates how simple modifications—such as injecting random node features—can significantly boost GNNs' ability to learn near-optimal approximation algorithms for fundamental graph problems like minimum dominating set and maximum matching. By bridging GNN theory with distributed computing and optimal transport, the lab explores both theoretical limits and practical applications of graph representation learning. The group also examines fairness and utility trade-offs in group recommendation systems, emphasizing equitable user satisfaction in collaborative settings.
Professor Takufumi Yanagisawa's research lab specializes in brain-machine interface (BMI) systems and neuroprosthetics, focusing on decoding motor intentions from neural signals—particularly electrocorticographic (ECoG) and magnetoencephalographic (MEG) signals—for real-time control of prosthetic limbs. The lab investigates neural mechanisms underlying motor control and cortical plasticity, including phase-amplitude coupling in high-gamma activity and synaptic reorganization in the sensorimotor cortex following injury or deafferentation. Their work bridges fundamental neuroscience with clinical applications, aiming to restore motor function in poststroke and severely paralyzed patients through BMI-driven neurorehabilitation.
Professor Yusuke Sakaguchi's research lab focuses on mesenchymal stem cell (MSC) biology, particularly the identification and characterization of MSCs from various tissue sources, including synovium and trabecular bone, to optimize their use in regenerative medicine. The lab also investigates the pathophysiology of chronic kidney disease (CKD), with a strong emphasis on mineral metabolism, such as magnesium homeostasis, and its impact on disease progression and outcomes. Additionally, the lab explores the clinical implications of comorbid conditions like obstructive sleep apnea (OSA) and erythropoiesis-stimulating agent (ESA) use in CKD and dialysis patients. Their work bridges stem cell science and nephrology, aiming to improve patient outcomes through translational research.
Professor Hiroya Abe's research lab specializes in advanced materials processing and nanostructured materials development, with a focus on thermal insulation materials, metallic glass processing, and powder metallurgy. The lab explores innovative dry powder techniques to fabricate fiber-reinforced fumed silica composites for high-performance thermal insulation, as well as the dealloying behavior of metallic glasses under controlled chemical environments. Key research directions include the design of porous, lightweight insulating materials and the fundamental understanding of selective leaching in amorphous alloys.
Professor Shusaku Sasaki's research lab specializes in behavioral economics and experimental social science, focusing on how nudges and social information influence prosocial and health-related behaviors. The lab investigates the design and impact of message-based interventions—particularly in public health contexts such as vaccination, infection control, and charitable giving—using large-scale online experiments and field data. A central theme is understanding how psychological and social cues, such as peer behavior or donation matching, affect individual decision-making without compromising autonomy. The lab also explores the role of identity, social norms, and information framing in shaping real-world behaviors.
Professor Ping Tang's research lab specializes in theoretical and computational condensed matter physics, with a focus on quantum materials and their emergent phenomena. Key research directions include the electronic and magnetic properties of battery materials—particularly olivine and other polymorphs of FePO₄ and LiFePO₄—ferroelectrics with novel quasiparticles like 'ferrons,' and spin transport in quantum materials such as antiferromagnets and systems exhibiting the orbital Hall effect. The lab employs advanced first-principles methods, including density functional theory and quantum transport theories, to explore phenomena ranging from multiferroicity and electric switching to spin pumping and thermoelectric responses in low-dimensional and van der Waals heterostructures.
