ソウル大学、KAIST、延世大学など韓国QSトップ10大学の研究室情報です。
Professor Yuree Lee's research lab focuses on plant cell signaling and membrane dynamics, with a central emphasis on phosphoinositides and their roles in regulating cellular processes such as stomatal movement, actin cytoskeleton organization, and organ abscission. The lab investigates how lipid second messengers like PtdIns(4,5)P2 and PtdIns3P modulate signal transduction in response to environmental cues and developmental signals. Using molecular genetics, live-cell imaging, and biochemical approaches in *Arabidopsis thaliana*, the lab explores the integration of stress and developmental pathways through lipid-mediated signaling. Recent work highlights the roles of phosphatidylinositol kinases, phospholipases, and reactive oxygen species in coordinating growth, stress responses, and reproductive success.
Professor Takhee Lee's research lab specializes in next-generation electronic and optoelectronic materials, with a strong focus on resistive memory devices, 2D materials, and perovskite-based semiconductors. The lab explores fundamental mechanisms of resistive switching in organic and perovskite materials, aiming to develop low-power, flexible, and printable memory technologies. It also investigates high-gain photodetectors using monolayer transition metal dichalcogenides and advanced nanocontacts for III-V semiconductors, emphasizing device performance and nanoscale interface engineering. A key theme across the research is the integration of novel materials with tailored electronic properties for energy-efficient and high-performance nanoelectronics.
Professor Sun Kwang Kim's research lab focuses on the neural mechanisms underlying neuropathic pain, with a particular emphasis on cortical and glial plasticity in the primary somatosensory cortex (S1) following peripheral nerve injury. The lab investigates the dynamic structural and functional rewiring of synaptic circuits, including dendritic spine plasticity and astrocyte-neuron interactions, to uncover novel therapeutic targets. Using advanced in vivo imaging and behavioral assays, the lab explores how pathological changes in the brain contribute to chronic pain and evaluates the efficacy of interventions such as bee venom acupuncture and its bioactive components in alleviating chemotherapy-induced allodynia.
Professor Seung Hun Han's research lab specializes in corporate finance, corporate governance, and asset pricing, with a strong focus on the role of information asymmetry, corporate social responsibility, and institutional governance in financial markets. The lab investigates how credit ratings, earnings disclosures, stock repurchases, and ownership structures affect firm valuation and investor behavior, particularly in emerging and developed markets such as Korea and the U.S. Key themes include the impact of governance quality, religious and cultural factors on investment decisions, and the signaling effects of financial policies. The lab employs empirical and event-study methodologies to analyze market reactions and corporate behavior under asymmetric information and agency conflicts.
Professor Seung-Kook Kim's research lab specializes in minimally invasive spinal surgery, with a primary focus on endoscopic and percutaneous spinal interventions such as trans-sacral epiduroscopic laser decompression (SELD) and water-tight dural repair techniques. The lab investigates clinical outcomes, procedural safety, and long-term functional recovery in patients with lumbar disc herniation, comparing endoscopic approaches to traditional microscopic open discectomy. Research also emphasizes improving surgical instrumentation, including novel dural protectors and knot pushers, to enhance surgical efficacy and reduce complications. The lab's work contributes to advancing less invasive, patient-friendly spinal surgery with reduced recovery times and lower complication rates.
Professor Hwiyoung Kim's research lab specializes in the application of artificial intelligence and machine learning to medical image analysis, with a focus on improving diagnostic accuracy and clinical decision-making in radiology and orthopedics. The lab develops explainable AI models and deep learning frameworks—such as multi-scale U-Net architectures—for automated segmentation and detection of anatomical structures, including organoids and pulmonary nodules. A key emphasis is on enhancing reproducibility and reliability in medical imaging, particularly through robust, interpretable, and adversarial-robust AI systems for clinical deployment. The lab also investigates psychosocial predictors in caregiver stress using machine learning, aiming to support early intervention in pediatric mental health.
Professor Sun Hwa Kim's research lab specializes in advanced drug delivery systems, with a primary focus on exosome-based therapeutics and nanocarrier technologies for targeted cancer therapy and tissue regeneration. The lab explores the biological functions of exosomes—particularly those derived from M2 macrophages—to reprogram immune cells and enhance wound healing, while also developing smart nanomaterials such as functionalized PLGA and PEG-based hydrogels for controlled release. A key research direction involves engineering surface-modified nanoparticles and polyelectrolyte complexes to improve cellular uptake and gene silencing efficiency in cancer cells through folate receptor targeting. The lab integrates principles of biomaterials, cell biology, and nanomedicine to design biocompatible, stimuli-responsive systems for precision medicine applications.
Professor Keun-Hwa Lee's research lab specializes in emerging infectious diseases, with a primary focus on tick-borne viral pathogens such as Severe Fever with Thrombocytopenia Syndrome virus (SFTSV) and Orientia tsutsugamushi. The lab investigates viral pathogenesis, host immune responses, and the development of novel diagnostics, vaccines, and therapeutics. Key research directions include understanding cytokine dysregulation in severe infections, improving early detection through CRISPR-based molecular diagnostics, and exploring host-vector-pathogen interactions in endemic regions.
Professor Yunsook Lim's research lab focuses on the therapeutic potential of natural bioactive compounds in managing metabolic and inflammatory diseases. The lab investigates the anti-obesity, anti-diabetic, and anti-inflammatory effects of plant-derived extracts—such as mulberry leaf and fruit extracts, genistein, gamma-tocopherol, and conjugated linoleic acid (CLA)—in preclinical models of obesity, diabetes, and impaired wound healing. A central theme is the modulation of oxidative stress, systemic and tissue-specific inflammation, and metabolic dysregulation through dietary interventions. The lab also explores the molecular mechanisms underlying these effects, particularly in liver and adipose tissues, with translational applications in metabolic syndrome and diabetic complications.
Professor Kyo Seon Hwang's research lab specializes in the development of advanced nanomechanical biosensors for label-free, real-time detection of biomolecular interactions. The lab focuses on micro- and nanoscale cantilever-based sensors that exploit changes in resonant frequency or surface stress upon biomolecule binding, enabling high-sensitivity detection in liquid environments. Key research directions include novel materials integration—such as PZT thin films and functionalized self-assembled monolayers—and the application of MEMS fabrication techniques to enhance device performance and portability. The lab also emphasizes quantitative modeling of surface stress to correlate mechanical responses with specific biological interactions.
Professor Sun Young Kim's research lab focuses on translational biomedical research with a strong emphasis on aging-related diseases, particularly sarcopenia and osteoporosis in the elderly Korean population. The lab integrates clinical epidemiology, body composition analysis using DXA, and biomarker discovery to identify early indicators of muscle and bone health decline. Additionally, the lab explores bioactive natural compounds from traditional medicinal plants for their antiplatelet and anticoagulant properties, aiming to develop novel therapeutics for cardiovascular protection. The research also extends to synthetic organic chemistry, including transition-metal-catalyzed cyclization reactions for the efficient construction of complex carbocyclic and heterocyclic frameworks with potential pharmaceutical relevance.
Professor Jewel Kumer Saha's research lab specializes in the development of high-performance, solution-processed oxide semiconductor thin-film transistors (TFTs) with a focus on spray pyrolysis deposition techniques. The lab explores novel materials and heterostructures—such as ZnO, AlZnO, YZnO, and doped ZnO—on various gate insulators (e.g., Al₂O₃, ZrOₓ) to enhance device mobility, stability, and scalability. Key research directions include defect engineering, surface passivation using rare-earth oxides (e.g., Y₂O₃, Gd₂O₃), and codoping strategies (e.g., Li/Gd) to simultaneously improve electrical performance and long-term reliability.
Professor Tae Woo Kim's research lab specializes in molecular oncology, focusing on the identification and mechanistic dissection of natural compounds and herbal formulations as novel anti-cancer agents in gastric cancer. The lab investigates key cellular processes such as autophagy, endoplasmic reticulum stress, and epigenetic regulation, particularly through HDAC inhibition, ER stress pathways (IRE1-JNK-CHOP, PERK-ATF4-CHOP), and epigenetic silencing (DNA methylation, histone modifications). A central theme is understanding how natural bioactive compounds—such as kaempferol, apigenin, cinnamaldehyde, and SH003—induce selective cancer cell death while overcoming therapy resistance, especially under hypoxic tumor microenvironments. The lab also explores PPARγ as a therapeutic target in non-small cell lung cancer, highlighting a translational focus on repurposing and designing novel ligands for cancer therapy.
Professor Je-Ho Mun's research lab specializes in dermatological diagnostics and therapeutics, with a primary focus on advancing non-invasive and accurate diagnostic methods for skin and nail disorders. The lab investigates the clinical applications of dermoscopy, reflectance confocal microscopy, and artificial intelligence in diagnosing conditions such as onychomycosis, subungual hemorrhage, and melanocytic neoplasms. Additionally, the lab explores repurposed drugs—like simvastatin and oral zinc sulfate—for treating fibrotic and viral skin conditions, including keloids and viral warts, emphasizing translational research that bridges clinical dermatology with molecular mechanisms.
Professor Sungkyoon Kim's research lab specializes in environmental health and toxicology, focusing on the biological effects of environmental pollutants, particularly benzene and endocrine-disrupting chemicals. The lab investigates the metabolic pathways and dose-response relationships of xenobiotics in humans, with an emphasis on biomarkers of exposure and susceptibility, including genetic polymorphisms. Using advanced statistical modeling and pharmacokinetic approaches, the lab explores how low-level environmental exposures influence metabolic and metabolic disease outcomes such as obesity and liver dysfunction.
Professor Young Soo Kim's research lab focuses on molecular oncology and neurodegenerative disease mechanisms, with a central emphasis on identifying and developing targeted therapeutic strategies for cancer and Alzheimer’s disease. The lab investigates apoptosis regulation in tumor cells, particularly through TRAIL and PPARγ ligands, and explores receptor-targeted delivery systems using cyclic peptides for selective cancer therapy. Additionally, the lab examines neuroprotective agents such as sulforaphane in Alzheimer’s disease models, highlighting the role of oxidative stress and the Nrf2-ARE pathway in neurodegeneration. The integration of molecular targeting, apoptosis modulation, and cytoprotective pathways defines the lab’s translational research approach.
Professor Jemin Kim's research lab specializes in translational biomedical research with a focus on dermatology, aging, and regenerative medicine. The lab investigates the gut-brain axis in relation to migraine and gastrointestinal disorders, explores the clinical efficacy of collagen peptides for skin rejuvenation and photoaging, and develops artificial intelligence models for objective scar assessment post-surgery. Additionally, the lab examines dermatological treatments for acne and related skin conditions, integrating clinical, biophysical, and imaging approaches.
Professor Changhoon Lee's research lab specializes in fluid dynamics and turbulence control, with a focus on leveraging advanced control theories and numerical simulations to reduce skin-friction drag in turbulent flows. The lab investigates adaptive and feedback control strategies—particularly those based on wall-shear stress and pressure measurements—using direct numerical simulations to develop practical, real-time drag reduction techniques. A key research direction involves manipulating near-wall coherent structures, such as vortices, through targeted body forces or electromagnetic actuation to suppress turbulence energy production. The lab also explores particle-laden flows, examining how heavy particles interact with turbulent coherent structures under gravity, especially in the context of deposition and transport dynamics.
Professor Hyun Ae Jung's research spans computational optimization and biomedical oncology, with a focus on algorithmic efficiency in multiprocessor scheduling for directed acyclic graphs (DAGs) with communication delays, as well as clinical research in cancer treatment. Her work includes investigating targeted therapies and chemotherapy regimens in advanced or recurrent cancers, particularly nasopharyngeal carcinoma and urothelial cancer, with an emphasis on efficacy, survival outcomes, and central nervous system involvement. She also explores the impact of systemic therapies like capecitabine and immunotherapy combinations on treatment-related toxicities and long-term outcomes. Her interdisciplinary approach bridges theoretical computer science and clinical oncology, aiming to improve both computational resource allocation and patient survival strategies.
Professor Neeraj Kumar Mishra's research lab specializes in transition metal-catalyzed C–H functionalization, with a strong focus on rhodium(III)-catalyzed transformations for the selective and efficient construction of complex nitrogen-containing heterocycles. The lab develops innovative strategies for site-selective functionalization of C–H bonds in indoles, indolines, and anilines using diverse coupling partners such as diazo compounds, amination agents, and olefins. Their work emphasizes atom-economical, step-efficient synthesis of medicinally relevant scaffolds, including cyanated, aminated, and alkenylated heterocycles with high functional group tolerance. The research also extends to the synthesis of biologically active compounds, including anticancer agents, through strategic C–H activation and cyclization processes.
