世界の主要大学の研究室を探索 — 研究分野と主要論文を一目で確認できます。
Professor Seung Joon Baek's research lab focuses on the molecular mechanisms underlying the chemopreventive and antitumorigenic effects of natural dietary compounds, particularly polyphenols and phytochemicals such as 6-gingerol, resveratrol, and green tea catechins. The lab investigates how these compounds modulate key signaling pathways—especially those involving NAG-1, Egr-1, and PPARγ—leading to apoptosis and cell cycle arrest in colorectal and other cancers. A central theme is the identification of PPARγ-independent mechanisms of action for anti-cancer agents, with a strong emphasis on transcription factor regulation and stress-response pathways. The lab also explores novel imaging tools, such as the lux system, for real-time visualization of biological processes in living cells.
Professor Young-Jun Lim's research lab specializes in biomaterials and oral implantology, focusing on the development and evaluation of titanium-based implant surfaces to enhance osseointegration and tissue response. The lab investigates the biomechanical and biological interactions between dental implants and host tissues, with particular emphasis on surface properties such as roughness and wettability. Additionally, the lab explores advanced drug delivery systems using electrospun fibers for chronic wound healing applications, especially in diabetic conditions. Their work integrates clinical imaging, computational modeling, and translational research to improve the accuracy and predictability of guided implant surgery.
Professor Sang-Kyu Ye's research lab focuses on the molecular mechanisms underlying cancer progression, neurodegenerative disorders, and inflammatory diseases, with a central emphasis on the role of STAT3 signaling in disease pathogenesis. The lab investigates how dysregulated signaling pathways—particularly IL-6/STAT3, NF-κB, and HIF-1α—contribute to tumor microenvironment formation, cancer stemness, and tissue damage in conditions such as liver cancer, colitis, and diabetic encephalopathy. A key research direction involves developing and evaluating small molecule inhibitors, such as ODZ10117, to target STAT3 for cancer therapy. The lab also explores the biological effects of physical forces, including simulated microgravity, on cancer cell behavior, revealing novel anticancer mechanisms.
Professor Soon-Tae Lee's research lab focuses on innovative neurotherapeutic strategies for neurological emergencies and neurodegenerative diseases, with a strong emphasis on translational neuroscience. The lab investigates neuroprotective mechanisms in stroke and epilepsy, exploring cell-based therapies such as neural stem cell transplantation, miRNA regulation of neurotrophic factors like BDNF, and novel drug delivery systems. A key focus is on developing personalized, implantable medical devices for real-time treatment of conditions like status epilepticus, integrating wireless monitoring with on-demand drug release. The lab also explores natural compounds, such as Panax ginseng, for cognitive enhancement in Alzheimer’s disease, combining preclinical and clinical approaches.
Professor Tae Hui Kim's research lab specializes in digital mental health interventions and neuropsychological assessment, with a focus on developing and evaluating brief, reliable, and culturally adapted tools for screening cognitive and mental health conditions in older adults. The lab investigates the efficacy of internet-based psychological therapies—such as iACT and iBA—across diverse populations, particularly in addressing depression, anxiety, and quality of life. A key research direction involves validating clinical instruments like the SMMSE-DS and FAB-K for use in diverse geriatric populations with varying educational backgrounds.
Professor Seong Wook Yang's research lab specializes in the development of novel nanomaterial-based biosensors, with a strong focus on DNA-silver nanoclusters (DNA/AgNCs) for sensitive and selective detection of microRNAs—key biomarkers in disease diagnosis and developmental regulation. The lab explores the fundamental principles of DNA-nanomaterial interactions, particularly how DNA secondary structures influence the formation and optical properties of AgNCs, enabling applications in multiplexed diagnostics and live-cell imaging. Additionally, the lab investigates molecular mechanisms in plant stress responses, especially the roles of phytochromes and ubiquitin-proteasome systems in regulating developmental plasticity under environmental stress. These interdisciplinary efforts bridge nanotechnology, molecular biology, and plant systems biology to create innovative tools for biomedical and agricultural biotechnology.
Professor Gilsoo Jang's research lab specializes in power system stability, control, and power quality enhancement, with a strong focus on nonlinear dynamics, harmonic mitigation, and HVDC integration. The lab develops advanced control strategies using nonlinear analysis techniques such as the method of normal forms to improve system resilience under stressed conditions. It also addresses challenges in high-penetration renewable integration and transmission system stability, particularly in small and isolated power systems. The lab's work emphasizes practical solutions through optimal reactive power compensation, fault analysis, and secure power flow control using PTDF and LODF formulations.
Professor James Jungho Pak's research lab specializes in advanced functional materials and their applications in energy conversion, micro-electromechanical systems (MEMS), and electronic devices. The lab focuses on developing novel nanomaterials such as ionic polymer-metal composites (IPMCs), cellulose-based fibers, and transition metal oxide/fluoride heterostructures for use in micro-actuators, micro-pumps, supercapacitors, and electrocatalysts for hydrogen evolution. Key research directions include resistive switching memory (RRAM) devices with multilayer insulating structures, scalable synthesis of ultrathin 2D materials like BiOCl, and electrowetting-based droplet manipulation for lab-on-a-chip systems. The lab emphasizes materials design, device fabrication, and comprehensive electrochemical and physical characterization to enable high-performance, stable, and scalable technologies.
Professor Han Ah Lee's research lab specializes in hepatology and metabolic liver disease, with a strong focus on the intersection of metabolic dysfunction–associated steatotic liver disease (MASLD), cardiovascular risk, and hepatocellular carcinoma (HCC). The lab investigates the pathophysiology, prognostic markers, and treatment outcomes in chronic liver diseases, particularly the transition from immune-tolerant to active hepatitis B, the role of immune cells like NK cells in HCC progression, and the impact of vascular invasion on HCC prognosis. The team also explores longitudinal risk factors and personalized management strategies for MASLD-related cardiovascular disease.
Professor Jaehyuck Jang's research lab specializes in nanophotonics and metamaterials, focusing on the design and application of advanced optical structures for sensing, imaging, and secure information technologies. The lab develops tunable structural color devices, including ultrafast humidity sensors and dynamic color printing, using materials such as chitosan hydrogels and dielectric metasurfaces. Key research directions include hybridized Mie-lattice resonances, Kerker's condition-based metasurfaces, and polarization-encrypted nanoprints for next-generation security and IoT applications. The lab bridges fundamental photonics with practical devices, emphasizing low-loss, high-sensitivity, and energy-efficient optical systems.
Professor Seog Ju Kim's research lab focuses on the neurobiological and psychological underpinnings of trauma-related disorders, particularly posttraumatic stress disorder (PTSD), ADHD, and sleep-wake disturbances in adolescents and young adults. The lab employs advanced neuroimaging techniques such as diffusion tensor imaging (DTI) to investigate white matter integrity and neurochemical markers like GABA in brain regions associated with emotion regulation and attention. A key research direction involves understanding how circadian phenotypes—such as morningness-eveningness preferences—and sleep patterns, including weekend catch-up sleep, contribute to cognitive and psychiatric outcomes. The lab also evaluates the efficacy of trauma-focused psychotherapies, such as narrative exposure therapy, in refugee populations and clinical populations with sleep and mood disorders.
Professor Geum-Youn Gwak's research lab focuses on the pathophysiological links between non-alcoholic fatty liver disease (NAFLD) and systemic metabolic and cardiovascular diseases. The lab investigates how NAFLD, even in the absence of obesity or traditional risk factors, contributes to the development of atherosclerosis, insulin resistance, diabetes, and colorectal neoplasia. A key research direction involves identifying high-risk subgroups—particularly those with 'lean NAFLD'—to enable early intervention and improve clinical outcomes. The lab also explores prognostic factors in hepatocellular carcinoma, especially in advanced-stage disease, to refine patient stratification and treatment strategies.
Professor Seon-Cheol Park's research lab focuses on the neurobiological and clinical aspects of mood and psychotic disorders, with a particular emphasis on the interplay between stress, inflammation, and depression. The lab investigates clinical phenotypes of major depressive disorder (MDD), including the role of age at onset and insomnia as key indicators of disease severity and prognosis. It also conducts systematic reviews and meta-analyses to evaluate treatment efficacy and safety, especially comparing long-acting injectable and oral second-generation antipsychotics in schizophrenia. The lab aims to improve diagnostic accuracy and treatment strategies through evidence-based psychiatry and translational research.
Professor Seung-Jun Shin's research lab specializes in smart manufacturing and industrial data analytics, focusing on the integration of big data, machine learning, and advanced sensing to enhance manufacturing efficiency, sustainability, and predictive capability. The lab develops intelligent systems for real-time monitoring, modeling, and optimization of manufacturing processes—particularly in metal cutting—by leveraging data-driven approaches and interoperable platforms like OPC UA. A key focus is enabling self-learning factories through holonic systems and hybrid learning models that allow machines to autonomously anticipate performance outcomes based on historical data and real-time conditions. The lab also explores cutting-edge nanoscale devices, such as ultra-small single-electron transistors, for next-generation smart manufacturing components.
本研究室では、加齢に伴う嗅覚機能の低下とその神経生物学的メカニズムを、マウスを用いた神経新生・細胞死の動態解析を通じて解明しています。また、COVID-19に伴う嗅覚障害の回復を促す嗅覚トレーニングの有効性や、その背後にある植物由来化合物の作用メカニズムについても、精油の成分と生物学的活性の関連を解明しています。さらに、漢方薬に用いられる甘草（ライコリス）の系統的同定と成分多様性の解明も進め、DNAマーカーを用いた分子的同定法の確立を目指しています。
福澤香織教授の研究室では、量子化学的手法を応用して生体分子間の相互作用を高精度で解析する研究を展開しています。特に、フラグメント分子軌道法（FMO）を用いたタンパク質・リガンド相互作用のエネルギー的解明や、がん治療薬の作用機構の理解を目指したエストロゲン受容体のリガンド親和性評価が中心です。また、宇宙空間における有機分子の生成経路の理論的解明や、研究データの共有を目的としたFMOデータベースの構築・公開も進めています。
阿部隆哉教授の研究室は、計算生物学とバイオインフォマティクスを基盤とし、特にタンパク質間相互作用の解明や創薬のための分子シミュレーション、高速な遺伝子配列解析手法の開発を主な研究テーマとしています。特に、タンパク質ドッキングや分子動力学シミュレーションを用いた膜透過性を有するサイクルペプチドの設計、およびメタゲノム解析における高速同義検索アルゴリズムの開発が顕著です。これらの研究は、がんや難治性疾患の標的療法に向けた新薬開発の基盤を提供しています。
Albert Escrivà教授の研究室は、初期宇宙における原始ブラックホール（PBH）の形成メカニズムに注目し、特に球対称な密度揺らぎがどのようにしてブラックホールへと崩壊するかを数値シミュレーションと解析的アプローチで解明しています。主に放射支配の宇宙背景下でのPBH形成閾値の普遍性や、非ガウス性、QCD転移付近での状態方程式の変化が質量関数に与える影響を研究しており、宇宙論的観測と理論の橋渡しを狙っています。
Shoji Kawakatsu教授の研究室は、消化器がん、特に胃がんや胆道がん、結腸がんに伴う肝転移や胆管転移の治療戦略に注力しています。特に腹腔鏡下手術や同時切除の安全性・有効性の検証が中心であり、術後の合併症や予後に与える影響を精査することで、高リスク患者に対する手術の妥当性を示しています。また、希少な転移例の報告を通じて、がんの生物学的挙動や治療タイミングの意義についても深く探求しています。
済田教授の研究室は、ポルフィリン類を核とした新規有機機能分子の合成とその機能解明を主軸としています。特に、縮合型ポルフィリン（サブポルフィリン）や拡張ポルフィリンの新規合成、ならびにその金属錯体や光学・非線形光学特性の解明が進んでいます。また、アザ-BODIPY誘導体を用いた高量子収率発光材料の開発や、近赤外領域への吸着・発光制御のための分子設計にも取り組んでいます。
