世界の主要大学の研究室を探索 — 研究分野と主要論文を一目で確認できます。
Professor Jung-Yun Lee's research lab focuses on understanding the molecular mechanisms underlying ovarian cancer pathogenesis, with a particular emphasis on high-grade serous ovarian cancer (HGSC) and rare subtypes such as mucinous and clear cell carcinomas. The lab investigates tumor heterogeneity, metastatic spread via transcoelomic dissemination, and the tumor immune microenvironment, especially T cell exhaustion and immune checkpoint regulation. Their work integrates clinical outcomes with molecular profiling to improve prognostic tools and identify novel immunotherapeutic targets, such as the co-stimulatory receptor 4-1BB. The lab also explores the chemopreventive potential of natural compounds like genistein in ovarian carcinogenesis.
大塚淳博教授の研究室は、ポルフィリンをはじめとする大環状キレート化合物の合成とその電子的・光学的性質の解明を柱としています。特に、メソ位やβ位に直接結合したポルフィリンアレイの構築により、広範なπ結合系を形成し、極めて赤ずれた吸光特性と低励起ギャップを示す新規構造体の創出に成功しています。また、人工光合成にインspiredされたサイクリックなポルフィリンアレイの設計や、励起エネルギー移動の制御といった光機能材料の開発にも注力しています。
Kazuya Kikuchi教授の研究室は、細胞内ジンクイオンや一酸化窒素などの生物学的シグナル分子を高感度でリアルタイムに可視化するための新規蛍光プローブの開発を柱としています。特に、FRET機構を応用したラティオメトリック測定が可能なプローブや、近赤外領域で発光する高感度プローブの設計が進んでいます。また、マルチモードイメージングを可能にする機能性ナノキャリヤーの開発を通じて、がん治療や細胞内動態の可視化に応用する研究も展開しています。
Kazuhiro Nakamura教授の研究室では、体温調節の中枢神経回路機構を解明することを主眼としています。特に、褐色脂肪組織における非ふるい性熱産生や筋肉におけるふるい性熱産生、皮膚からの熱受容情報の伝達経路、および発熱反応を引き起こす神経回路の解明に注力しています。脳幹の視床下部前帯領域や縫線核、外側縫線核などの神経核を標的とし、自律神経系と運動系の統合的制御を神経回路レベルで解明しています。
Professor Myung Jun Kim's research lab specializes in the fundamental understanding and control of anisotropic growth mechanisms in metal nanostructures, particularly copper, through electrochemical and surface science approaches. The lab investigates how organic capping agents and halide ions selectively influence facet-specific deposition kinetics, enabling precise shape control for applications in nanoelectronics, catalysis, and energy conversion. By combining single-crystal electrochemistry, in situ electrochemical analyses, and advanced characterization, the lab uncovers the molecular-level origins of nanostructure formation and develops strategies for bottom-up fabrication of functional nanomaterials. Their work also extends to electrochemical processes in nanostructured electrodes, such as Cu nanowire felts, for high-productivity electrocatalysis and energy storage devices.
Professor Nakwon Choi's research lab specializes in developing advanced in vitro models to mimic the complex microenvironments of the human brain, with a focus on brain tumors, neurodegenerative diseases, and neural tissue function. The lab integrates bioengineered platforms such as 3D organoids, brain-on-a-chip systems, and decellularized extracellular matrix (dECM) hydrogels to enable high-fidelity modeling of neural physiology, including blood-brain barrier function and cell-cell interactions. Their work emphasizes the creation of physiologically relevant, high-content platforms for drug screening, disease modeling, and understanding neurological pathologies at the cellular and molecular levels.
Professor Jack J. Yoh's research lab specializes in the numerical and experimental investigation of high-energy reactive systems, with a focus on thermal explosion phenomena, deflagration-to-detonation transition (DDT), and the combustion dynamics of solid propellants and energetic materials. The lab employs advanced computational modeling—particularly ALE3D and semi-implicit Runge-Kutta methods—alongside laser diagnostics and thermal analysis to study complex reaction mechanisms in confined and reactive environments. Key research directions include electrically controlled solid propellants, laser-induced plasma and ablation, and the hydrodynamic behavior of reactive flows under extreme conditions. The work bridges fundamental chemistry, fluid dynamics, and materials science to enable safer and more efficient energetic systems.
M. Michael Gromiha教授の研究室では、タンパク質の安定性と折りたたみ速度の予測を主軸とした計算生物学的研究が進められています。特に、アミノ酸配列からタンパク質の折りたたみ速度を予測するFOLD-RATEサーバーや、突然変異がもたらす安定性変化を予測する統計的モデルの構築が特徴です。また、熱安定性を示すタンパク質の構造的・エネルギー的要因の解明にも注力しており、産業的応用に向けたタンパク質工学の基盤を提供しています。
Professor Sunkyu Yu's research lab specializes in theoretical and applied wave physics, focusing on topological phenomena in non-Euclidean geometries, deterministic bandgap engineering in disordered systems, and the design of novel optical materials using symmetry principles and quantum-inspired frameworks. The lab explores the interplay between geometry, topology, and wave transport, with applications in hyperbolic lattices, Fano resonances, and chiral light-matter interactions. By leveraging concepts such as supersymmetry, Bohmian mechanics, and metadisorder, the lab develops deterministic methods for controlling wave localization, absorption, and phase dynamics in complex systems.
Professor Jaewook Lee's research lab specializes in the intersection of data science, financial modeling, and advanced materials engineering. The lab focuses on developing robust machine learning and graph-based models for financial volatility forecasting and option pricing, particularly for illiquid or extreme market conditions. It also investigates the mechanical and acoustic properties of polymer composites through experimental design and material optimization. Additionally, the lab explores biometric authentication using evolutionary algorithms and topological clustering methods for real-world applications in cybersecurity and data analysis.
Professor Changsoon Choi's research lab specializes in the development of soft, flexible, and bio-integrated electronic systems with a focus on next-generation wearable and implantable biomedical devices. The lab pioneers advanced optoelectronic and neuromorphic technologies that mimic human biological systems, particularly the visual and neural systems, for applications in medical imaging, retinal stimulation, and robotic vision. Key research directions include hemispherically curved image sensors using 2D materials like MoS₂-graphene heterostructures, on-chip image pre-processing using synaptic photodetectors, and bio-inspired artificial vision systems with high performance under complex environments.
Professor Kyong-Taek Kim's research lab specializes in cellular signaling and calcium dynamics, with a focus on the physiological mechanisms underlying hormone secretion in neuroendocrine cells. The lab investigates the distinct roles of intracellular and extracellular calcium sources in regulating exocytosis, particularly in bovine adrenal medullary cells, using advanced techniques such as fura-2 ratiometric imaging and amperometric detection. Their work reveals fundamental differences in the functional outcomes of calcium mobilization from internal stores versus extracellular influx, highlighting the specialized regulatory roles of each calcium pool. The lab also explores the impact of pharmacological agents, such as dimethyl isobutylamine, on calcium signaling and secretory processes.
Professor William Jo's research lab specializes in the epitaxial growth and fundamental characterization of advanced functional oxide thin films, with a focus on superconducting, ferroelectric, and hybrid perovskite materials. The lab investigates the structural, electrical, and optical properties of these films to enable next-generation optoelectronic and electronic devices. Key research directions include the development of high-quality single-crystalline perovskites, c-axis-oriented ferroelectric thin films with tailored electro-optic responses, and superconducting MgB2 thin films with high transition temperatures. The lab employs advanced pulsed laser deposition and molecular-beam epitaxy techniques to achieve precise control over film orientation, defect engineering, and interface properties.
Koji Hagihara教授の研究室では、希土類元素を含有するマグネシウム合金に現れる長周期積層構造(LPSO相)の微細組織と変形挙動の関係を解明し、高度な強化機構を追求しています。特に、圧延や方向凝固、Additive Manufacturing(3Dプリント)を用いた微細制御により、LPSO相の形状・配列・テクスチャーを制御し、超強度・高靭性マグネシウム合金の創出を目指しています。また、LPSO相の原子レベルの不純度やスターリング・フォールド構造が機械的性質に与える影響についても、高分解能電子顕微鏡や圧縮試験を組み合わせて解明しています。
Minakata教授の研究室では、酸化・還元反応を活用した新しい炭素–ハロゲン・窒素結合形成反応の開発に注力しています。特に、t-BuOIを用いた酸化的な置換反応や、水中での有機反応の効率的実現が特徴です。また、窒素含有六員環や五員環の合成法の確立を通じて、医薬品や天然物の合成に応用可能な新規反応機構の解明を進めています。
Hiroshi Ogura教授の研究室は、敗血症や重篤な外傷に伴う全身性炎症反応と凝固・血小板活性化の連関を解明することを主眼としています。特に、血小板の活性化がマイクロパーティクル形成や好中球との好酸球接着を促進するメカニズムに与える影響を、臨床的・実験的アプローチで解明しています。SIRS(全身性炎症反復症候群)と関連する凝固障害が臓器障害を引き起こすメカニズムの解明にも注力しており、敗血症の病態生理と治療指針の高度化を目指しています。
Narihito Nagoshi教授の研究室は、脊髄損傷の再生医療をめざし、神経前駆細胞の幹細胞的特性を活かした細胞移植療法の開発を主眼としています。特に、ヒト induced pluripotent stem cells(iPSC)から作られる神経前駆細胞を用いた、脱髄神経線維の修復や神経回路の再生を促す治療戦略の確立を目指しています。また、神経細胞の活動を制御する chemogenetic 刺激技術を応用し、移植細胞の機能的統合を高める新規アプローチの開発も進めています。
Professor Ga Eun Nam's research lab focuses on the epidemiological and clinical investigation of obesity, metabolic syndrome, and their long-term health implications, particularly in relation to neurodegenerative diseases and cardiovascular outcomes. The lab specializes in population-based cohort studies to identify modifiable risk factors such as body weight variability, BMI, and waist circumference in Korean adults. Key research directions include understanding the links between metabolic health, obesity phenotypes, and the development of type 2 diabetes, dementia, and cardiovascular diseases. The lab also contributes to national health policy by evaluating and refining obesity diagnostic criteria tailored to the Korean population.
Professor Seokchan Yoon's research lab specializes in advanced optical imaging and atomic physics, focusing on overcoming fundamental limitations in biomedical imaging and quantum optics. The lab develops innovative optical techniques—such as reflection-matrix microscopy and tailored magneto-optical traps—to correct for complex optical aberrations in living tissues and to achieve precise control of single or few atoms. Their work spans from improving deep-tissue imaging in neuroscience to advancing high-precision atomic manipulation for quantum technologies. The lab also contributes to atmospheric science by analyzing aerosol and pollution profiles using lidar and remote sensing techniques.
Professor Jeyoung Park's research lab specializes in advanced polymer science and sustainable materials, focusing on the development of functional polymers and nanomaterials for environmental and biomedical applications. The lab pioneers innovative polymer architectures—such as star-shaped rod–coil copolymers and chitin/chitosan-based nanomaterials—aimed at enhancing recycling efficiency, enabling upcycling of plastic waste, and creating biodegradable, high-performance materials. Key research directions include green polymer synthesis, multiscale nanostructure engineering, and translational applications in food packaging, biomedicine, and environmental remediation.