世界の主要大学の研究室を探索 — 研究分野と主要論文を一目で確認できます。
Professor Won Keun Oh's research lab specializes in natural product-based drug discovery, with a primary focus on identifying bioactive compounds from medicinal plants and marine organisms for the treatment of metabolic and neurodegenerative diseases. The lab investigates molecular mechanisms underlying metabolic regulation, particularly through key enzymes such as acetyl-CoA carboxylase 2 (ACC2), protein tyrosine phosphatase 1B (PTP1B), and AMP-activated protein kinase (AMPK). Current research directions include the development of therapeutic agents targeting type 2 diabetes, obesity, Alzheimer’s disease, and breast cancer using natural compounds with antioxidant, anti-inflammatory, and enzyme-inhibitory activities. The lab employs advanced techniques such as bioassay-guided fractionation, high-resolution mass spectrometry, and spectroscopic analysis to isolate and characterize novel bioactive molecules.
Professor Hyun Woo Lee's research lab focuses on the intersection of environmental health, bone metabolism, and respiratory diseases. The lab investigates the long-term impacts of air pollutants like PM₂.₅ and NO₂ on chronic obstructive pulmonary disease (COPD), while also exploring molecular mechanisms regulating osteoblast and adipocyte differentiation in bone marrow. Key research directions include the role of adiponectin and berberine in osteogenesis, as well as clinical outcomes in non-small cell lung cancer (NSCLC) and sepsis management. The lab integrates molecular signaling, transcriptional regulation, and clinical epidemiology to identify therapeutic targets for metabolic and respiratory disorders.
Professor Duhwan Mun's research lab specializes in digital transformation and intelligent design automation within the engineering and manufacturing domains. The lab focuses on advancing automated conversion of engineering drawings—particularly image-format piping and instrumentation diagrams (P&IDs)—into structured digital formats using deep learning and computer vision. Key research directions include 3D CAD model reconstruction from 2D data, topology-aware recognition of engineering symbols and lines, and seamless parametric CAD model exchange across heterogeneous design systems. The lab also addresses challenges in collaborative product development, such as consistent engineering change management and persistent feature referencing in distributed design environments.
Kanai教授の研究室は、神経伝達物質であるグルタメートのシナプス後除去に不可欠な輸送体の分子機構を解明することを主眼としています。特に、グルタミン酸を高親和性で取り込む神経細胞および星細胞に発現する輸送体の同定と機能解析を進めています。また、アミノ酸輸送体（例：LAT1）の構造的・機能的特徴と、神経可塑性や神経毒性に関連するメカニズムの解明にも注力しています。
Chihiro Yoshimura教授の研究室は、淡水生態系における有機物の動態と食物網の構造を解明することを目的としています。特に、細粒有機物（FPOM）の化学的性質、微生物呼吸、および現場での分解速度に着目し、粗粒有機物（CPOM）がどのように変換・利用されるかを、エラーフィッシュ（ガマールス）を用いた実験で解明しています。日本の多様な河川環境をモデルとして、陸域と水域の物質循環やエコシステム機能の理解を深めています。
Hiroyuki Suzuki教授の研究室は、有機金属化学と無機化学の分野において、特にシルコンと硫黄を含む新しい結合性化合物の創出に注力しています。特に、キネティック的に安定なシリル硫黄二重結合（シランチオン）の合成と構造解析を世界的に先駆けて実現しました。また、その反応機構や不斉環境下での反応性の制御についても深く研究しており、新規機能性分子の設計に貢献しています。
Professor Sae Hun Kim's research lab specializes in probiotic microbiology and functional dairy science, focusing on the health-promoting effects of lactic acid bacteria and their fermented products. The lab investigates mechanisms by which specific Lactobacillus strains—such as *L. acidophilus*, *L. plantarum*, and *L. fermentum*—modulate gut health, bone metabolism, and cholesterol reduction. Key research directions include the development of probiotic microencapsulation techniques, the role of fermented milk products in treating postmenopausal osteoporosis, and the identification of bacterial factors involved in cholesterol metabolism. The lab integrates microbiological, molecular, and physiological approaches to translate probiotic mechanisms into practical health applications.
Professor Woong-Suk Yang's research lab specializes in bioactive peptides and functional foods derived from plant-based sources, with a focus on soy and oats. The lab investigates the physiological and therapeutic properties of bioactive compounds such as isoflavones, β-glucan, and fermented soy products like cheonggukjang, emphasizing their roles in preventing chronic diseases, improving gut health, and modulating immune and inflammatory responses. A key research direction involves identifying and characterizing natural bioactive peptides and phytochemicals with antiallergic, antihypertensive, and cholesterol-lowering effects.
Professor Hyung Joo Suh's research lab specializes in bioactive natural products, focusing on the functional properties and mechanisms of plant- and microbe-derived compounds for health and cosmetic applications. Key research directions include the development of anti-aging, anti-stress, and anti-fatigue agents using fermented botanicals such as red ginseng, rice bran, and mulberry extract. The lab also investigates the biochemical stability and kinetic behavior of natural pigments and antioxidants under various processing conditions. These studies aim to translate traditional herbal knowledge into evidence-based nutraceutical and cosmetic ingredients with enhanced efficacy and safety.
Professor Seong-Gyu Ko's research lab specializes in identifying and characterizing bioactive compounds from traditional herbal medicines for their therapeutic potential in cancer, neurodegenerative diseases, and inflammatory disorders. The lab focuses on elucidating molecular mechanisms underlying the anti-tumor, anti-inflammatory, and neuroprotective effects of herbal extracts and their active ingredients, particularly through modulation of key signaling pathways such as STAT3, NF-κB, and autophagy. Their work integrates in vitro cell culture studies with in vivo animal models to validate therapeutic efficacy and safety.
Kondoh教授の研究室では、金属粉末の焼結挙動とその微細構造制御に注目し、特にマグネシウムの添加がアルミニウム合金粉末の界面反応に与える影響をXPSを用いた表面分析を通じて解明しています。焼結密度や機械的性質の向上機構を、表面酸化膜の還元作用に起因するとし、ナノスケールの界面反応機構の解明を進めています。また、焼結部材の破壊メカニズムと微細組織の関係についても、破断面のひずみ局在を評価する手法を応用しています。
福勢康一教授の研究室では、細菌の細胞壁を構成するペプチドグリカンの構造と生物学的機能の解明を柱に、糖鎖の効果的合成とその免疫活性メカニズムの解明を進めています。特に、N-Troc保護を用いたステレオ選択的グリコシル化反応の開発により、ペプチドグリカンの短鎖断片を効率的に合成し、がん免疫療法への応用を狙った新規医薬候補の創出を目指しています。
Tamotsu Yoshimori教授の研究室は、細胞内のオートファジー機構とその機能、特に病原体に対する細胞の防御機構や代謝疾患における役割を解明することを主眼としています。特に、リソソームの酸性化制御やオートファジーが細菌感染に対しどのように作用するかを細胞生物学的・分子生物学的に解明しています。また、NAFLD（非アルコール性脂肪肝疾患）におけるオートファジーの制御機構や、Rubiconというタンパク質の病態関与についても革新的な知見を提供しています。
藤木祐夫教授の研究室は、細胞小器官の一つであるペルオキシソームの膜構造とその膜タンパク質の生物学的機能、特にタンパク質の輸送・膜形成機構に焦点を当てた研究を行っています。特に、ペルオキシソームへのタンパク質輸送に不可欠なPTS1受容体Pex5の機能的ドメインや、膜タンパク質の合成・挿入機構の解明を進めています。また、ヒトのペルオキシソーム生合成障害症（例：ゼルウェルガー症候群）の遺伝的基盤を、中国キメラザメ由来細胞（CHO）突然変異株を用いた機能補完系で解明しています。
Hailong Fan教授の研究室は、バイオハイドロゲルやグラフェンを含むナノ複合材料の開発に注力しており、特に水中での接着性・機械的強度・生体適合性を兼ね備えた新規材料の創出を目的としています。主にタンニン酸（TA）を用いた超分子的自己修復性・耐久性を持つハイドロゲルや、カチオン-π相互作用を活用した塩水中でも強力な接着性を示すポリマー材料の設計・合成を進めています。また、自然由来の分子構造を模倣したスマートマテリアルの創出が、医療・環境・産業分野への応用を視野に研究が展開されています。
Professor Sang-Bum Kim's research lab specializes in neuromorphic computing and brain-inspired electronics, focusing on developing next-generation computing systems that emulate the efficiency and adaptability of the human brain. The lab explores emerging memory devices such as phase-change memory (PCM) and memristors, with an emphasis on in-situ learning, low-power operation, and hardware implementation of spike-based learning algorithms like STDP. A key direction involves integrating novel materials and nanostructures—such as organic electrochemical transistors (OECTs) and 2T-1R PCM architectures—for applications in real-time biological signal processing, intelligent information retrieval, and energy-efficient AI hardware. The lab also investigates fundamental device behaviors, including resistance drift and thermal stability, to enhance reliability in neuromorphic systems.
Professor Osman M. Karatepe's research lab specializes in organizational behavior and human resource management, with a focus on employee well-being, job performance, and organizational outcomes in service industries. The lab investigates key constructs such as psychological capital, emotional exhaustion, work-family conflict, job embeddedness, and emotional labor, often within hospitality and retail sectors. Drawing on theoretical frameworks like the conservation of resources theory, job demands-resources model, and social exchange theory, the lab emphasizes empirical testing through structural equation modeling and longitudinal designs. Research directions include the impact of leadership, work environment, and individual psychological resources on employee engagement, innovation, and turnover intentions.
Professor Gynheung An's research lab specializes in plant molecular biology and functional genomics, with a primary focus on rice genetics and developmental biology. The lab employs T-DNA tagging and activation tagging to identify and characterize genes involved in critical developmental processes such as flowering time, tapetum development, and male fertility. Utilizing reverse genetics approaches, including gene overexpression and RNAi, the lab investigates the molecular mechanisms underlying stress responses and reproductive development in rice. Their work integrates molecular genetics, genomics, and physiological analyses to dissect gene function in monocotyledonous crops.
Otake教授の研究室では、金属有機フレームワーク（MOFs）を基盤とした高機能材料の設計・創出を柱としています。特に、酸化触媒やプロトン伝導性材料としての応用を視野に入れ、金属を単原子として均一に担持した新規触媒や、ナノスケールの水の構造・動態を解明する結晶性ナノチューブ材料の開発を進めています。結晶構造と物性の相関を精密に解明するため、X線単結晶構造解析や可変温度分光法を駆使した分子レベルの理解が特徴です。
Watabe教授の研究室は、がん治療における標的療法やイメージング技術の開発を柱としており、特にFibroblast Activation Protein（FAP）を標的にしたPET・診療核医学や、α線放出核種を用いたがん治療の最適化を進めています。また、代謝酵素の働きや標的薬物送達系の化学的安定性向上についても、分子レベルでのメカニズム解明を進めています。特に、211Atを用いた標的α線療法における化学的純度向上や、FAPインヒビターの臨床的応用可能性の評価が顕著です。
