Bon-Kwon Koo
Seoul National University · 医学
研究室紹介
Professor Bon-Kwon Koo's research lab specializes in interventional cardiology and vascular imaging, focusing on the physiological assessment of coronary artery disease using fractional flow reserve (FFR) and intracoronary imaging techniques such as IVUS and OCT. The lab investigates hemodynamic and anatomical determinants of restenosis, plaque vulnerability, and optimal revascularization strategies in complex coronary interventions. A key research direction involves evaluating the long-term outcomes of antiplatelet therapy and functional assessment in percutaneous coronary intervention, with a strong emphasis on personalized, physiology-guided revascularization. The lab also pioneers the integration of advanced imaging and radiomics to identify high-risk plaques and improve risk stratification in patients with coronary artery disease.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15In conclusion, FFR-guided SB intervention strategy resulted in good functional outcomes.
BACKGROUND: We sought to investigate the mechanism of geometric changes after main branch (MB) stent implantation and to identify the predictors of functionally significant "jailed" side branch (SB) lesions. METHODS AND RESULTS: Seventy-seven patients with bifurcation lesions were prospectively enrolled from 8 centers. MB intravascular ultrasound was performed before and after MB stent implantation, and fractional flow reserve was measured in the jailed SB. The vessel volume index of both the pr
Background: Long-term outcomes of antiplatelet monotherapy in patients who receive percutaneous coronary intervention are unknown. The HOST-EXAM (Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis–Extended Antiplatelet Monotherapy) Extended study reports the posttrial follow-up results of the original HOST-EXAM trial. Methods: From March 2014 through May 2018, 5438 patients who maintained dual antiplatelet therapy without clinical events for 12±6 months after percutaneous cor
AIMS: Identification of invasive and radionuclide imaging markers of coronary plaque vulnerability by a single, widely available non-invasive technique may provide the opportunity to identify vulnerable plaques and vulnerable patients in broad populations. Our aim was to assess whether radiomic analysis outperforms conventional assessment of coronary computed tomography angiography (CTA) images to identify invasive and radionuclide imaging markers of plaque vulnerability. METHODS AND RESULTS: We
In patients with intermediate stenosis who were being evaluated for PCI, FFR guidance was noninferior to IVUS guidance with respect to the composite primary outcome of death, myocardial infarction, or revascularization at 24 months. (Funded by Boston Scientific; FLAVOUR ClinicalTrials.gov number, NCT02673424.).