Byung-Bin Ryu
Yonsei University · 医学
研究室紹介
Professor Byung-Bin Ryu's research lab specializes in pediatric pharmacology, focusing on the unique pharmacokinetic and pharmacodynamic profiles of children, particularly neonates and infants. The lab investigates developmentally influenced changes in drug absorption, distribution, metabolism, and excretion to optimize medication safety and efficacy in pediatric populations. Key research directions include modeling age-dependent physiological changes and translating these insights into clinical dosing strategies. The lab also explores the impact of organ immaturity on drug response, aiming to improve therapeutic outcomes in pediatric patients.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
1Purpose: Pediatric pharmacotherapy requires a thorough understanding of developmental physiology and the distinct pharmacokinetic (PK) and pharmacodynamic (PD) characteristics of this population. Unlike adults, children (particularly neonates and infants) exhibit substantial differences in drug absorption, distribution, metabolism, and excretion as a result of immature organ function and rapid developmental changes. These characteristics must be considered for safety and efficacy in pediatric ph